Medicine and Health Sciences Commons^™

Perimenopausal Depression Screening And Treatment Efficacy Between Antidepressants And/Or Hormone Replacement Therapy, Mandy Stenehjem

Physician Assistant Scholarly Project Posters

During perimenopause, women are at increased risk of depression due to complex and multifactorial factors, such as HPA axis dysregulation and fluctuations in hormones, like estradiol. Antidepressants are currently used to treat depression, but hormone replacement therapy may also have comparable antidepressant effects based on hormonal mechanisms. Perimenopausal depression is a unique subtype of depression and needs to be routinely screened by OBGYNs and primary care providers. The literature review found mixed results on the efficacy of HRT, antidepressants, and a combination of both; all treatments have shown promising benefits and specific screening may be needed to tailor treatment.

Decreasing Suicidal Risks Among Military Veterans With Posttraumatic Stress Disorder Or Major Depression, Manpreet K. Sheabat

Physician Assistant Scholarly Project Posters

Suicide is a major cause of death in US. Military personnel are at a higher risk of committing suicide compared to the general population. The risk is exacerbated by Posttraumatic Stress Disorder (PTSD) and major depression.

• Few reviews have explored the effects of the recommended psychotherapeutic interventions on suicidal ideations and suicide rates for these two disorders, focusing on the veteran population. To address this, a literature search was performed through electronic databases to identify appropriate journal articles.

• Treatment with CPT and PE for PTSD has been found effective in decreasing suicidal thoughts, intents, and attempts. On the …

Use Of Marijuana In Those With Anxiety And Depression, Heather Flaa

Physician Assistant Scholarly Project Posters

The purpose of this research and literature review was to compare the use of marijuana to SSRIs in reducing anxiety and depression symptoms.

• This literature review searched databases Cochrane, PubMed, Clinical Key, PsycINFO, and DynaMed Plus from the year 1990 and on. Keywords: cannabis, marijuana, anxiety, generalized anxiety disorder, depression, and selective serotonin reuptake inhibitors.

• Many meta-analyses show SSRIs continue to be first line treatment in those with anxiety and depression in reducing symptoms.

• Patients with marijuana use showed an increased odds ratio of developing anxiety and depression or increasing symptoms in several studies.

• No studies …

Treatment Option Decision Making For Low-Grade Prostate Cancer, Janene Witherite

Physician Assistant Scholarly Project Posters

Prostate cancer (PCa) is the second most common cancer, among men, in the United States.

 Low-grade PCa is defined by; lack of metastasis outside the prostate (M0), no lymph node involvement (N0), tumor staging up to T2a, a PSA of less than 10 ng/ml, a Gleason score of less than 6, and no more than two of the 10-12 tissue samples (each composed of less than 50% cancer cells) of the 10-12 samples taken.

 Four treatment options exist for low-grade PCa patients: active surveillance (AS), external beam radiotherapy (EBRT), brachytherapy, and radical prostatectomy (RP), all of which cause …

The Gut-Brain Axis: Treating Depression Through Microbiome Alterations, Alexandria Bachman-Williams

Physician Assistant Scholarly Project Posters

• The purpose of this study is to explore the role of gut microbiome alterations in the treatment of anxiety and depression. • There are multiple pathological pathways that lead to the development of anxiety and depression. • Research shows a link between pathologic bacteria and low grade inflammation. This causes a disruption of neurotransmitters that are current targets of pharmacological treatment of depression and anxiety. • Transfer of “pathogenic” bacteria caused increased symptoms of anxiety and depression. • Treatment with probiotics and “protective” bacteria showed decreased BDI scores and improved symptoms. • Studies were small but show need for …

Analysis Of Tech-Based And Telemental Health Approaches Within The Adolescent And Young Adult Populations Of Rural America, Audrey K. Smeenk

Physician Assistant Scholarly Project Posters

The incidences of depression and anxiety among adolescent and young adult populations are intensifying, and resources remain limited for the management of these diseases within rural America.

• Evaluation on different interventions was completed to assess ease of access, efficacy, and patient adherence with the hope to decrease incidence of disease and increase availability of resources to rural areas.

• Based on the current completed research, there is a predominance of evidence that has shown moderate statistical data and promising outcomes from tech-based mobile applications and telemental health. Statistical evidence supports that technological based interventions are a potential treatment option …

Provider Suicide, Amy Quinn

Physician Assistant Scholarly Project Posters

The purpose of this research and systematic literature review is to determine the risks factors for, the identification of and repercussions of provider suicide. In this review, databases searched included Pubmed , Cochran Database of Systematic Reviews, PsycInfo , National Institute of Health, Medscape and Google Scholar from September 8, 2018 to January 13, 2019. A variety of key terms were used when searching include suicide, provider suicide, suicide, costs of suicide, physician burnout, physician assistant burnout, nurse burnout, doctor suicide, physician assistant suicide, and nurse practitioner suicide . Works chosen for review were published between 1979 and 2018, as …

Outcomes In Treatment Of Major Depressive Disorder: Pharmacogenomic Testing Vs. Treatment As Usual, Zachary Horoshak

Physician Assistant Scholarly Project Posters

The goal of this scholarly project was to evaluate the efficacy of pharmacogenomic testing (PGx) versus treatment as usual (TAU) in the treatment of major depressive disorder (MDD). According to Huang & Lin (2015), MDD is characterized by multiple signs and symptoms consisting of mood, vegetative, cognitive, and even psychotic behaviors that may cause substantial impairment in the functioning and quality of life in an affected individual. This literature review consisted of articles found in PubMed, Cochrane, and PsychINFO which were extensively reviewed. Articles prior to 2008 were excluded due to the ever-changing landscape of PGx testing. In this review, …

The Impact Of Shift Work On Health And Wellbeing, Stephanie Gagelin

Physician Assistant Scholarly Project Posters

Many of today’s industries require workers to perform shift work (typically during 1600-0700). If workers are awake during this time period, circadian misalignment occurs. This scholarly project uses research studies and metaanalyses to provide information about increased health risks associated with circadian misalignment, focusing on the categories of glucose metabolism, cardiovascular system, carcinogenesis, and mental health and acuity.

• Shift work has been found to increase BMI and waist circumference of employees, as well as increase blood glucose levels to “prediabetic” levels in previously euglycemic individuals.

• Shift work has been proven to increase high-sensitivity C-reactive protein (hs-CRP), an acute …