Medicine and Health Sciences Commons^™

Safety And Efficacy Of Apixaban Vs Rivaroxaban: In Nonvalvular Atrial Fibrillation, Cody Dewitt

Physician Assistant Scholarly Project Posters

• Introduction: Nonvalvular atrial fibrillation, the most common cardiac arrhythmia in developed countries, warrants anticoagulation for stroke prevention. Updated guidelines recommend direct oral anticoagulants (DOACs) over historically used warfarin. The purpose of this review is to compare clinical safety and efficacy outcomes between apixaban and rivaroxaban. • Research Questions: In patients with nonvalvular atrial fibrillation on a direct oral anticoagulant, is there a significant difference in safety and efficacy between apixaban and rivaroxaban? Does decreased kidney function change safety and efficacy? Does varying BMI such as low weight or obesity change safety and efficacy? • Methods: A retrospective literature review …

Childhood Obesity: Adding Metformin To Lifestyle Modification For Weight Reduction, Kelli Strege

Physician Assistant Scholarly Project Posters

One of the most challenging health conditions primary care providers face is combating the ever-rising incidence of obesity, especially among children. The objective of this literature review is to determine the effects of metformin implemented in addition to lifestyle modification for the treatment of childhood obesity. Efficacy, to include change in weight, BMI, insulin resistance, and overall safety of metformin was studied. The online databases searched in this review were PubMed, Cochrane Library, Embase, and CINAHL. Literature chosen for review included randomized control trials, meta-analysis, and systematic reviews published between 2015 and 2020. Much of the studied research indicates positive …

The Impact Of Shift Work On Health And Wellbeing, Stephanie Gagelin

Physician Assistant Scholarly Project Posters

Many of today’s industries require workers to perform shift work (typically during 1600-0700). If workers are awake during this time period, circadian misalignment occurs. This scholarly project uses research studies and metaanalyses to provide information about increased health risks associated with circadian misalignment, focusing on the categories of glucose metabolism, cardiovascular system, carcinogenesis, and mental health and acuity.

• Shift work has been found to increase BMI and waist circumference of employees, as well as increase blood glucose levels to “prediabetic” levels in previously euglycemic individuals.

• Shift work has been proven to increase high-sensitivity C-reactive protein (hs-CRP), an acute …