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Full-Text Articles in Medicine and Health Sciences
Intranasal Opioid Compositions, Daniel Wermeling
Intranasal Opioid Compositions, Daniel Wermeling
Pharmaceutical Sciences Faculty Patents
The present invention relates to pharmaceutical compositions for intranasal administration to a mammal that contain an effective amount of an opioid, a liquid nasal carrier for the opioid, and optionally a sweetener, flavoring agent or masking agent. In some embodiments of the present invention, the pharmaceutical compositions have improved bioavailability. In other embodiments of the present invention, the opioid compositions improve patient compliance.
Water Soluble Amine Esters Of Testosterone For Intranasal Administration, Anwar A. Hussain
Water Soluble Amine Esters Of Testosterone For Intranasal Administration, Anwar A. Hussain
Pharmaceutical Sciences Faculty Patents
The present invention provides novel water soluble testosterone analogs. These testosterone analogs are suitable for intranasal administration to patients requiring increased plasma testosterone levels. The present invention also provides pharmaceutical compositions containing the testosterone analogs of the present invention. The present invention further provides a method of increasing plasma testosterone levels in patients in need of such treatment comprising the intranasal administration of the water-soluble testosterone analogs and pharmaceutical compositions of the present invention.
Nasal Administration Of Propranolol, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi
Nasal Administration Of Propranolol, Anwar A. Hussain, Shinichiro Hirai, Rima Bawarshi
Pharmaceutical Sciences Faculty Patents
The invention relates to a novel method of administering propranolol, a known β-andrenergic blocking agent widely used in the treatment of angina pectoris, arrhythmias, hypertension and other cardiac conditions, and migraine. The invention further relates to novel dosage forms of propranolol which are adapted for nasal administration and which include solutions, suspensions, gels and ointments.