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Does Sarilumab 200mg Result In Functional Improvement In Patients With Rheumatoid Arthritis Who Cannot Tolerate The Traditional Line Of Treatment?, Emily P. Andreano
Does Sarilumab 200mg Result In Functional Improvement In Patients With Rheumatoid Arthritis Who Cannot Tolerate The Traditional Line Of Treatment?, Emily P. Andreano
PCOM Physician Assistant Studies Student Scholarship
Objective: The objective of this selective EBM review is to determine whether or not Sarilumab 200mg results in functional improvement in patients who cannot tolerate the traditional line of treatment in rheumatoid arthritis.
Study Design: Review of three randomized control trials (RCTs), published after 2013 all in the English language
Data Sources: 1 double blind, RCT comparing sarilumab 200mg against traditional treatment of TNF-alpha inhibitor adalimumab. 2 RCTs comparing efficacy of sarilumab 200mg to different dosages in patients that had an inadequate response or were unable to tolerate methotrexate (MTX) or TNF-a inhibitor. All studies were found using PubMed.
Outcomes …