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Articles 1 - 25 of 25
Full-Text Articles in Medicine and Health Sciences
Methods And Applications For Mesenchymal Stem Cells, Eman A. Ahmedy, Hala M. Gabr, Khaled A. Khalifa, Samar M. Kamal, Samia H. Kandel, Samia H. Rizk
Methods And Applications For Mesenchymal Stem Cells, Eman A. Ahmedy, Hala M. Gabr, Khaled A. Khalifa, Samar M. Kamal, Samia H. Kandel, Samia H. Rizk
Menoufia Medical Journal
Objective The aim of this work is to study neurogenesis using mesenchymal stem cells (MSCs) as a model of stem cells and then follow them as they form neurons. Background MSCs are multipotent adult stem cells present in all tissues. They are present in the bone marrow, and can differentiate in vitro into neurons, glial cells, and myofibroblasts. MSCs have been proposed as sources of stem cells for regeneration of the central nervous system. Thus, one of the goals of regenerative medicine is to ameliorate irreversible destruction of brain tissue and spinal cord by harnessing the power of stem cells …
Evaluation Of Nitric Oxide And Superoxide Dismutase In Different Stages Of Chronic Kidney Disease, Asmaa M. El-Gamacy, Emad F. Abd-Elhalim, Gehan K. El-Saeed, Mahmoud A. Koura, Seham A. Khodeer
Evaluation Of Nitric Oxide And Superoxide Dismutase In Different Stages Of Chronic Kidney Disease, Asmaa M. El-Gamacy, Emad F. Abd-Elhalim, Gehan K. El-Saeed, Mahmoud A. Koura, Seham A. Khodeer
Menoufia Medical Journal
Objective The aim of this work was to evaluate nitric oxide (NO) and superoxide dismutase (SOD) as parameters of oxidative stress in different stages of chronic kidney disease (CKD) and their correlation with the lipid profile. Background CKD is a debilitating disease that leads to many complications, the most common being cardiovascular. Hence, this study was carried out to evaluate the oxidative stress that predisposes to cardiovascular diseases in these patients. Methods This study included 60 patients with CKD. In addition, 12 apparently healthy age-matched and sex-matched individuals were included as a control group. Patients were classified into five groups …
Evaluation Of Rhegmatogenous Retinal Detachment Treatment By Pars Plana Vitrectomy Alone Versus Pars Plana Vitrectomy With A Scleral Buckle, Adel G. Zaky, Amin F. Ellakwa, Hamouda H. Ghoraba, Khaled G. Said, Saber H. El Sayed
Evaluation Of Rhegmatogenous Retinal Detachment Treatment By Pars Plana Vitrectomy Alone Versus Pars Plana Vitrectomy With A Scleral Buckle, Adel G. Zaky, Amin F. Ellakwa, Hamouda H. Ghoraba, Khaled G. Said, Saber H. El Sayed
Menoufia Medical Journal
Objective The aim of this study was to compare and report the anatomic and functional results of primary vitrectomy with scleral buckling versus primary vitrectomy without scleral buckling for the treatment of rhegmatogenous retinal detachment (RRD). Background RRD is one of the commonly encountered retinal problems where timely treatment could prevent irreversible vision loss. A variety of options, including scleral buckling, pars plana vitrectomy (PPV) with scleral buckling, pneumatic retinopexy, and a temporary balloon buckle, have been described as methods for repair of RRD. Patients and methods A prospective, interventional, comparative case study was carried out. This study included 170 …
Predictive Ability Of First-Day Serum Bilirubin And Haptoglobin For Subsequent Significant Hyperbilirubinemia In Healthy-Term And Near-Term Newborn, Ahmed A. Khattab, Dalia M. El-Lahony, Fady M. El-Gendy, Fahima M. Hassane, Noha M. Ashour
Predictive Ability Of First-Day Serum Bilirubin And Haptoglobin For Subsequent Significant Hyperbilirubinemia In Healthy-Term And Near-Term Newborn, Ahmed A. Khattab, Dalia M. El-Lahony, Fady M. El-Gendy, Fahima M. Hassane, Noha M. Ashour
Menoufia Medical Journal
Objective Predicting significant neonatal hyperbilirubinemia using cord blood haptoglobin and bilirubin on the first day of life. Background Neonatal jaundice is the result of an imbalance between the production and elimination of bilirubin. Bilirubin conjugation in newborns is significantly impaired in the first few days; even a small increase in the rate of production can contribute toward the development of hyperbilirubinemia. Hemolysis plays a significant role in bilirubin increase in newborns. When hemolysis takes place, a decrease in the haptoglobin blood level-binding hemoglobin in the environment occurs. Patients and methods A total of 61 healthy newborns of at least 35 …
The Role Of Soluble Transferrin Receptor In Iron Overload In Children With Chronic Hemolytic Anemia, Farida H. El-Rashidi, Fathia M. El-Nemr, Reda I. Rakha, Samar M.K. El-Din Fathallah, Seham M. Ragab
The Role Of Soluble Transferrin Receptor In Iron Overload In Children With Chronic Hemolytic Anemia, Farida H. El-Rashidi, Fathia M. El-Nemr, Reda I. Rakha, Samar M.K. El-Din Fathallah, Seham M. Ragab
Menoufia Medical Journal
Objectives The current study was conducted to study the pathophysiology of iron overload in children with chronic hemolytic anemia (thalassemia major, thalassemia intermedia, and sickle cell anemia) and to assess the utility of soluble transferrin receptor (sTfR) for the evaluation of iron overload. Background Iron overload is a major complication of repeated blood transfusion in patients with chronic hemolytic anemia. sTfR, one of the main regulators of cellular iron homeostasis, is the truncated form of the tissue receptor. Patients and methods Sixty children with chronic hemolytic anemia (20 thalassemia major, 20 thalassemia intermedia, and 20 sickle cell anemia) were included, …
Immunolocolization Of Cd29 In Keloid, Iman M. Elwan, Mohamed A. Basha, Ola Bakry, Rehab M. Samaka
Immunolocolization Of Cd29 In Keloid, Iman M. Elwan, Mohamed A. Basha, Ola Bakry, Rehab M. Samaka
Menoufia Medical Journal
Objective To shed light on the role of mesenchymal stem cells (MSCs) in keloid pathogenesis. Background Keloids are fibroproliferative scars that show a benign yet quasineoplastic behavior and morphology, as evidenced by high recurrence and aggressive invasion into the surrounding skin. MSC populations originate from bone marrow (BM) stroma, which can give rise to stromal mature mesenchymal cells and aid regeneration of the BM microenvironment. Human BM-derived MSCs may contribute toward keloid pathogenesis. Patients and methods A total of 30 skin biopsy specimens from keloid lesions were used and 15 healthy volunteers were used as a control. Histopathological examination of …
Kidney Injury Molecule-1 As An Early Marker For Acute Kidney Injury In Critically Ill Patients, Ibrahim M. Boghdady, Karim S. Mahmoud, Mahmoud M. Emara, Mostafa M. El Naggar, Rania M. El-Shazly
Kidney Injury Molecule-1 As An Early Marker For Acute Kidney Injury In Critically Ill Patients, Ibrahim M. Boghdady, Karim S. Mahmoud, Mahmoud M. Emara, Mostafa M. El Naggar, Rania M. El-Shazly
Menoufia Medical Journal
Objective The aim of this study was to evaluate the role of kidney injury molecule-1 (KIM-1) as an early marker for acute kidney injury (AKI) in critically ill patients as compared with conventional markers (e.g. serum creatinine). Background Depending on traditional markers for renal functions, namely, blood urea and serum creatinine, has led to unacceptable delay in the diagnosis of AKI and in initiating treatment. Materials and methods This study included 89 individuals: 79 critically ill patients and 10 healthy individuals who served as controls. All patients were prospectively followed up from the time of ICU admission. Blood and urine …
Calcium-Sensing Receptors, Biology, And Clinical Significance: A Systemic Review, Ahmed R. Tawfeek, Ali Z. Galal, Karam S. Mostafa, Sabry A. Shoeb
Calcium-Sensing Receptors, Biology, And Clinical Significance: A Systemic Review, Ahmed R. Tawfeek, Ali Z. Galal, Karam S. Mostafa, Sabry A. Shoeb
Menoufia Medical Journal
This is a study of calcium-sensing receptors (CaSR), biology, and clinical significance. The CaSR plays an essential role in the regulation of extracellular calcium (Ca 2+ ) homeostasis. CaSR is expressed in all tissues related to this control (parathyroid glands, thyroid C cells, kidneys, intestine, and bones) and also in tissues with apparently no role in the maintenance of extracellular Ca 2+ levels, such as the brain, skin, and pancreas. CaSR cloning was immediately followed by the association of genetic human diseases with inactivating and activating CaSR mutations: Familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism are caused by CaSR-inactivating mutations, …
Molecular And Phenotypic Characterization Of Hospital-Associated And Community-Associated Isolates Of Enterococcus Spp., Al Ragehy A. Nahed, Elmasry A. Eman, Labib Z. Azza, Mahmoud B. Ahmed, Zahran A. Wafaa
Molecular And Phenotypic Characterization Of Hospital-Associated And Community-Associated Isolates Of Enterococcus Spp., Al Ragehy A. Nahed, Elmasry A. Eman, Labib Z. Azza, Mahmoud B. Ahmed, Zahran A. Wafaa
Menoufia Medical Journal
Objectives The aim of our study was to estimate the extent of spread of enterococcal infection as well as vancomycin-resistant enterococci (VRE) colonization at Menofia University Hospitals. and also to delineate occurrence and species prevalence, characterize VRE phenotypes and genotypes by multiplex PCR, and detect esp virulence genes in the enterococcal isolates from different sources. Background Enterococci are part of normal intestinal flora of both humans and animals; however, they have also emerged as significant community-acquired pathogens and are a leading cause of nosocomial infection. Patients and methods In this study, patients were classified into three groups. Group 1 included …
Dual Diagnosis And Psychosocial Correlates In Substance Abuse In Menoufia, Egypt, Afaf Z. Rajab, Lamia G. El Hamrawy, Mohamed S. El Bahy, Mohamed R. Soltan, Nabil R. Mohamed, Samy A. Hammad
Dual Diagnosis And Psychosocial Correlates In Substance Abuse In Menoufia, Egypt, Afaf Z. Rajab, Lamia G. El Hamrawy, Mohamed S. El Bahy, Mohamed R. Soltan, Nabil R. Mohamed, Samy A. Hammad
Menoufia Medical Journal
Objectives To study the comorbid psychiatric disorders among substance abusers in Menoufia and to identify whether there is a correlation between the type of substance and the comorbid disorder that occurred, and also to determine whether there are specific risk factors that can cause this comorbidity. Background A dual diagnosis presents a challenging problem to clinicians as substance use disorders occurring together with mental health disorders represent a major health problem. Participants and methods Study participants comprised 120 Egyptian substance abusers. They were subjected to the following: semistructured interview sheet, Fahmy and El Sherbini Social Classification scale, semistructured clinical interview …
Relationship Between Mthfr Polymorphism And Side Effects Of High-Dose Methotrexate In Pediatric Acute Lymphoblastic Leukemia, Ashraf A. Dawood, Farida H. El Rashedy, Mahmoud A. El-Hawy, Seham M. Ragab
Relationship Between Mthfr Polymorphism And Side Effects Of High-Dose Methotrexate In Pediatric Acute Lymphoblastic Leukemia, Ashraf A. Dawood, Farida H. El Rashedy, Mahmoud A. El-Hawy, Seham M. Ragab
Menoufia Medical Journal
Objectives To study the relationship between plasma methotrexate (MTX) level, methylenetetrahydrofolate reductase (MTHFR) gene polymorphism, and the occurrence of complications associated with high-dose methotrexate (HDMTX) in pediatric acute lymphoblastic leukemia (ALL). Background ALL is the most common type of cancer in children. Administration of HDMTX, followed by leucovorin rescue is an important component in the treatment of childhood ALL. MTX toxicity mainly includes mucositis, myelosuppression, and hepatic toxicity. MTX toxicity can vary with genetic variability in folate-metabolizing enzymes (e.g. MTHFR). Patients and methods A total of 26 ALL children were studied. Clinical assessments, laboratory detection of complete blood …
Cardiac Troponin I As An Early Predictor Of Perinatal Asphyxia, Ahmed T. Mahmoud, Ayat Shebl, Maha El-Bassuny
Cardiac Troponin I As An Early Predictor Of Perinatal Asphyxia, Ahmed T. Mahmoud, Ayat Shebl, Maha El-Bassuny
Menoufia Medical Journal
Objective The objective of this study was to test the hypothesis that cardiac troponin I (cTnI), a known marker of myocardial injury, is also an early predictor of both severity and mortality in cases of perinatal hypoxia. Background Delivery is a stressful and risky event that poses a risk to newborns. The mother-dependent respiration has to be replaced by autonomous pulmonary breathing immediately after delivery. If delayed, it may lead to deficient oxygen supply, compromising the survival and development of the central nervous system. The outcomes of perinatal asphyxia are devastating and permanent, making it a major burden for the …
Study On The Use Of Impulse Oscillometry In The Evaluation Of Children With Asthma, Fathea M. El-Nemr, Mohamed I. Al-Ghndour
Study On The Use Of Impulse Oscillometry In The Evaluation Of Children With Asthma, Fathea M. El-Nemr, Mohamed I. Al-Ghndour
Menoufia Medical Journal
Objective The aim of this study was to determine the use of impulse oscillometry in the evaluation of children with asthma and to analyze lung parameters, order effect, and utility, compared with spirometry. Background Asthma is a disease characterized by ongoing inflammation of the airway, overproduction of mucus, and airway constriction due to tightened muscles, which results in permanent structural changes in the lungs, a condition often called airway remodeling. In turn, these changes usually lead to accelerated declines in lung function, including irreversible decreases in airflow because of narrowed air passages. The Impulse Oscillometry System measures respiratory impedance using …
Impact Of Stone Density On The Outcome Of Extracorporeal Shock Wave Lithotripsy, Eid A. Elsherif, Mohamed H. Hamed, Sultan M. Sultan, Tarek M. Abdel-Elbaky
Impact Of Stone Density On The Outcome Of Extracorporeal Shock Wave Lithotripsy, Eid A. Elsherif, Mohamed H. Hamed, Sultan M. Sultan, Tarek M. Abdel-Elbaky
Menoufia Medical Journal
Objectives This study aims to evaluate the attenuation of renal calculi measured by Hounsfield unit (HU) by noncontrast spiral computerized tomography (NCSCT) as a predictor of calculus fragmentation by extracorporeal shock wave lithotripsy (SWL). Background The outcome of extracorporeal SWL is measured in terms of stone fragmentation and clearance. Some authors have suggested that HU of renal calculi by NCSCT may predict stone-free rates after extracorporeal SWL. Patients and methods This prospective nonrandomized open study included 100 patients with renal stone up to 20 mm in size. Stone attenuation was measured by HU on NCSCT. Patients were grouped according to …
The Role Of Transrectal Ultrasound-Guided Biopsy In Diagnosis Of Prostate Cancer, Basma A. El-Moniem Dessouky, Samer T. Gaffer, Waleed A. El-Fattah
The Role Of Transrectal Ultrasound-Guided Biopsy In Diagnosis Of Prostate Cancer, Basma A. El-Moniem Dessouky, Samer T. Gaffer, Waleed A. El-Fattah
Menoufia Medical Journal
Objectives The aim of this study was to evaluate the role of transrectal ultrasonography (TRUS)-guided biopsy in the detection of prostate cancer in patients on the basis of elevated prostate-specific antigen levels and abnormal digital rectal examination (DRE) results. Background The TRUS-guided biopsy technique was regarded as the golden standard method for diagnosis of prostate cancer. This study aimed to identify an appropriate prostate biopsy protocol for the detection of prostate cancer. Materials and methods This study included 30 patients having symptoms suggestive of prostatic diseases. All these patients were subjected to DRE, serum prostate-specific antigen testing, transabdominal ultrasound examination …
Ultrasonography Diagnostic Validity In Structural And Functional Laryngeal Disorders, Hazem A.A. Shalaby, Mohamed A. Maaly, Tarek F. Abdella
Ultrasonography Diagnostic Validity In Structural And Functional Laryngeal Disorders, Hazem A.A. Shalaby, Mohamed A. Maaly, Tarek F. Abdella
Menoufia Medical Journal
Objectives The aim of the study was to assess the role of ultrasound in detecting and characterizing laryngeal anatomy with a special focus on vocal cords and study of some laryngeal disorders and their possible ultrasonographic appearance. Background Laryngeal examination with rigid endoscopy has the advantages of producing large, bright images. Unfortunately, patients with a sensitive gag reflex, patients with limited jaw or neck mobility, or those with stridor may not tolerate laryngeal endoscopic examination. It is also difficult in most infants and children. Thus, high-resolution (frequency) laryngeal ultrasonography may provide an alternative diagnostic tool. Patients and methods The study …
Garlic Improves Altered Vascular Reactivity And Plasma Lipids In High Cholesterol-Fed Rats, Eman Rahman, Sally S. Donia, Yahya M. Naguib
Garlic Improves Altered Vascular Reactivity And Plasma Lipids In High Cholesterol-Fed Rats, Eman Rahman, Sally S. Donia, Yahya M. Naguib
Menoufia Medical Journal
Objective The aim of this work was to study the effect of garlic on the lipid profile of hypercholesterolemic rats and investigate the vascular reactivity to norepinephrine and acetylcholine in hypercholesterolemic rats treated with garlic in-vitro experiments. Background Hypercholesterolemia is considered an important risk factor for the development of atherosclerosis; currently, there is a major trend to use herbal remedies for the treatment and prevention of hypercholesterolemia and garlic is used for this purpose. Methods Forty male rats were divided into the following four groups of 10 animals each: (i) normal diet-fed animals (control), (ii) hypercholesterolemic animals, (iii) hypercholesterolemic garlic-treated …
Prevalence Of Depression, Anxiety, And Obsessive–Compulsive Disorders Among Secondary School Students In Menoufia Governorate, Egypt, Gaafar M. Abdel-Rasoul, Nabil R. Mohamed, Omaima A. Mohamed, Rabei A. Al Bahnasy, Reda A. Ibrahem
Prevalence Of Depression, Anxiety, And Obsessive–Compulsive Disorders Among Secondary School Students In Menoufia Governorate, Egypt, Gaafar M. Abdel-Rasoul, Nabil R. Mohamed, Omaima A. Mohamed, Rabei A. Al Bahnasy, Reda A. Ibrahem
Menoufia Medical Journal
Objectives The aim of this study was to estimate the prevalence of depression, anxiety, and obsessive–compulsive disorders among secondary school students and to assess the comorbidities of these disorders. Background Any type of mental illness can have a negative impact on cognitive development and learning and involves a very high cost to both the individual and society. Anxiety and depression can be considered reliable indicators for the assessment of mental illness in a community. Participants and methods From a total of 83 635 secondary school students in Menoufia Governorate during the academic year 2010–2011, using a multistage random sampling technique, …
The Role Of Microalbuminuria In Population Screening For Chronic Kidney Disease In An Egyptian Village, Mahmoud E. Abu Salem, Manal A. El Batanony, Omaima A. Mahrous, Rabie E. El Bahanasy, Wesam S. Mourad, Zeinab A. Kasemy
The Role Of Microalbuminuria In Population Screening For Chronic Kidney Disease In An Egyptian Village, Mahmoud E. Abu Salem, Manal A. El Batanony, Omaima A. Mahrous, Rabie E. El Bahanasy, Wesam S. Mourad, Zeinab A. Kasemy
Menoufia Medical Journal
Objectives The study aimed at determining the prevalence of and risk factors for chronic kidney disease (CKD) using microalbuminuria (MA) as a screening test in a rural area in Gharbia Governorate. Background CKD is being increasingly recognized as a public health problem. There is still paucity of data on the prevalence of and risk factors for CKD by using MA as a screening test in the Middle East. Methods A randomly chosen sample of 320 apparently healthy individuals were interviewed in Shennera village in Gharbia Governorate using a structured questionnaire including information about risk factors for MA. They were also …
Neurobehavioral, Respiratory, And Auditory Disorders Among Mercury-Exposed Fluorescent Lamp Workers, Gaafar M. Abdel-Rasul, Heba K. Allam, Mahmoud A. Abu-Salem, Manal A. Al-Batanony, Mervat M. Al-Dalatony
Neurobehavioral, Respiratory, And Auditory Disorders Among Mercury-Exposed Fluorescent Lamp Workers, Gaafar M. Abdel-Rasul, Heba K. Allam, Mahmoud A. Abu-Salem, Manal A. Al-Batanony, Mervat M. Al-Dalatony
Menoufia Medical Journal
Objective The aim of this work was to study some of the health disorders resulting from occupational exposure to mercury among workers in a fluorescent lamp factory. Background With the fast market growth of fluorescent lamps, the associated emissions and risk of mercury, which is an essential component in all types of fluorescent lamps, have received increasing public attention worldwide. Low doses of mercury exert toxicity on various human organs, including the central nervous, renal, respiratory, reproduction, immune, cardiovascular, skin, and motor systems. Methods A cross-sectional study was carried out on 138 workers in a fluorescent lamp factory and a …
Infection In Diabetic Foot, Ajlan E. Soma, Al-Mallah I. Said, Asif J. Fatani, Eed M. Emad, Eissa A. Naira, Mahmoud B. Ahmed
Infection In Diabetic Foot, Ajlan E. Soma, Al-Mallah I. Said, Asif J. Fatani, Eed M. Emad, Eissa A. Naira, Mahmoud B. Ahmed
Menoufia Medical Journal
Objectives The present study was carried out to determine the prevalence of aerobic and anaerobic pathogens in diabetic foot infections (DFIs), detect their susceptibility to different antimicrobial agents, investigate the microbiological profiles of DFIs in relation to different grades of Wagner classification, and assess the risk factors for DFIs. Background DFI is the most frequent reason for diabetes-related hospitalization. It develops because of several diabetes-related factors including arterial insufficiency, neuropathy, foot deformities, previous ulcers, previous amputation, and local trauma. Materials and methods The study was carried out on clinical specimens taken from 100 diabetic patients (50 patients had type I …
Pasd1 Gene Expression In Acute Myeloid Leukemia Patients, Ahmed Ragheb, Ali Z. Glal, Enas S. Essa, Ibrahim M. Baghdady, Mohamed A. Abd El Hafez, Sabry A. Shoeab, Tamer M. Ahmed
Pasd1 Gene Expression In Acute Myeloid Leukemia Patients, Ahmed Ragheb, Ali Z. Glal, Enas S. Essa, Ibrahim M. Baghdady, Mohamed A. Abd El Hafez, Sabry A. Shoeab, Tamer M. Ahmed
Menoufia Medical Journal
Objective To detect the expression of the PASD1 gene in acute myeloid leukemia (AML) patients and its relation to clinical features and complete remission of AML. Background AML is a heterogeneous disease with variable clinical outcomes. PASD1 [Per ARNT Sim (PAS) Domain containing protein 1] can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various malignancies, including AML. Materials and methods The study was carried out on 60 AML patients (group I) and 30 healthy controls (group II). Reverse transcriptase PCR analysis of the PASD1 gene was carried out …
Fibroblast Growth Factor 23 As A Risk Factor Of Left Ventricular Hypertrophy And Vascular Calcification In Predialysis Chronic Kidney Disease Patients, Ahmed M. Elmahmoudy, Eman M. Zahir, Hany Elbarbary, Hassan Abdel-Hady, Said S.A. Khamis, Yassein S. Yassein
Fibroblast Growth Factor 23 As A Risk Factor Of Left Ventricular Hypertrophy And Vascular Calcification In Predialysis Chronic Kidney Disease Patients, Ahmed M. Elmahmoudy, Eman M. Zahir, Hany Elbarbary, Hassan Abdel-Hady, Said S.A. Khamis, Yassein S. Yassein
Menoufia Medical Journal
Objective The objective of this study was to evaluate the possible role of fibroblast growth factor 23 (FGF23) in the occurrence of left ventricular hypertrophy and vascular calcification in predialysis chronic kidney disease (CKD) patients. Background FGF23 is a suggested risk factor for poor outcome of CKD. This raises the possibility that FGF23 is a hormone that controls calcium–phosphorus metabolism and is a real risk factor for cardiovascular mortality and morbidity in predialysis CKD patients. Materials and methods Thirty predialysis CKD patients with estimated glomerular filtration rate (90≥eGFR>15 ml/min/1.73 m2) by the modification of diet in renal diseases formula …
The Toxic Effect Of Phthalate On Testes Of Albino Rats And The Possible Protective Role Of Curcumin, Fatma El-Safti, Fouad K. Mansour, Neveen M. El-Sherif, Rasha M.A. Salama
The Toxic Effect Of Phthalate On Testes Of Albino Rats And The Possible Protective Role Of Curcumin, Fatma El-Safti, Fouad K. Mansour, Neveen M. El-Sherif, Rasha M.A. Salama
Menoufia Medical Journal
Objectives The aim of this study was to determine the toxic effect of di-n-butylphthalate (DBP) on the testes of developing and adult albino rats and to establish the possible protective role of curcumin. Background DBP is an endocrine-disrupting chemical that disrupts the growth of normal male reproductive organs of adult and developing rats after prenatal exposure. Methods The rats used in this study received DBP alone as well as in combination with curcumin and were subjected to biochemical (measuring the level of testosterone), histological, immunohistochemical, and morphometric (analysis of the mean diameter of the seminiferous tubules) studies. Results …
Compliance Of Diabetic Patients With The Prescribed Clinical Regimen, Ayat R. Ahamed, Ayman A. Attyia, Mahmoud E. Abu Salem, Manal A. Al-Batanony, Rabie E. El Bahnasy
Compliance Of Diabetic Patients With The Prescribed Clinical Regimen, Ayat R. Ahamed, Ayman A. Attyia, Mahmoud E. Abu Salem, Manal A. Al-Batanony, Rabie E. El Bahnasy
Menoufia Medical Journal
Objectives This study aimed at studying the prevalence of noncompliance among diabetic patients in Gharbia governorate in Egypt as well its causes, its effect on glycemic control, and factors affecting it. Background There is growing evidence suggesting that because of the alarmingly low rates of compliance, increasing the effectiveness of compliance interventions may have a great impact on the health of the population. Promotion of therapeutic compliance is considered an integral component of patient care. It has been shown that despite effective methods of treatment, many diabetic patients fail to achieve satisfactory glycemic control, which leads to accelerated development of …