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Full-Text Articles in Medicine and Health Sciences
Obesity, Physical Activity, And Their Interaction In Incident Atrial Fibrillation In Postmenopausal Women, Farnaz Azarbal, Marcia L. Stefanick, Elena Salmoirago-Blotcher, Joann E. Manson, Christine M. Albert, Michael J. Lamonte, Joseph C. Larson, Wenjun Li, Lisa W. Martin, Rami Nassir, Lorena Garcia, Themistocles L. Assimes, Katie M. Tharp, Mark A. Hlatky, Marco V. Perez
Obesity, Physical Activity, And Their Interaction In Incident Atrial Fibrillation In Postmenopausal Women, Farnaz Azarbal, Marcia L. Stefanick, Elena Salmoirago-Blotcher, Joann E. Manson, Christine M. Albert, Michael J. Lamonte, Joseph C. Larson, Wenjun Li, Lisa W. Martin, Rami Nassir, Lorena Garcia, Themistocles L. Assimes, Katie M. Tharp, Mark A. Hlatky, Marco V. Perez
Medicine Faculty Publications
Background Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with increased risk of stroke and death. Obesity is an independent risk factor for AF, but modifiers of this risk are not well known. We studied the roles of obesity, physical activity, and their interaction in conferring risk of incident AF.
Methods and Results The Women's Health Initiative (WHI) Observational Study was a prospective observational study of 93 676 postmenopausal women followed for an average of 11.5 years. Incident AF was identified using WHI‐ascertained hospitalization records and diagnostic codes from Medicare claims. A multivariate Cox's hazard regression …