Medicine and Health Sciences Commons^™

Spheroid Toxicity Assay Utilizing Magnetic 3d Bioprinting, Anore Pedalino, Ka Bian, Phd

Journal of Health Disparities Research and Practice

Analysis of cell cultures utilizing two-dimensional (2D) spheroid assays has been the standard to analyze toxicity screenings for decades, however the high cost and inefficiencies in producing in-vitro assays using this technique creates the need for more productive and cost-efficient methods. The newly introduced Magnetic 3D Bioprinting system addresses the shortcomings of the 2D systems. This method relies on magnetizing cells and rapidly printing them in a more organized formation, mimicking in-vitro environments and interaction. This study assesses the effectiveness of Magnetic 3D Bioprinting system in analyzing spheroid toxicity assays when compared to the 2D methods, we hypothesize that …