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Community Health and Preventive Medicine
Oral;; Aged;; Bone Density Conservation Agents/administration & dosage/therapeutic use;; Diphosphonates/administration & dosage/*therapeutic use;; Endometrial Neoplasms/epidemiology/*prevention & control;; Female;; Follow-Up Studies;; Humans;; Incidence;; Middle Aged;; *Postmenopause;; Prospective Studies;; Risk Assessment/methods/*statistics & numerical data;; Risk Factors;; Time Factors;; United States/epidemiology
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Full-Text Articles in Medicine and Health Sciences
Oral Bisphosphonate Use And Risk Of Postmenopausal Endometrial Cancer, P. A. Newcomb, M. N. Passarelli, A. I. Phipps, G. L. Anderson, J. Wactawski-Wende, G. Y. Ho, M. J. O'Sullivan, R. T. Chlebowski
Oral Bisphosphonate Use And Risk Of Postmenopausal Endometrial Cancer, P. A. Newcomb, M. N. Passarelli, A. I. Phipps, G. L. Anderson, J. Wactawski-Wende, G. Y. Ho, M. J. O'Sullivan, R. T. Chlebowski
Journal Articles
PURPOSE: Bisphosphonates are common medications used for the treatment of osteoporosis and are also used to reduce metastases to bone in patients with cancer. Several studies, including the Women's Health Initiative (WHI), have found that use of bisphosphonates is associated with reduced risk of developing breast cancer, but less is known about associations with other common malignancies. This study was aimed at examining the effects of bisphosphonates on the risk of endometrial cancer. METHODS: We evaluated the relationship between use of oral bisphosphonates and endometrial cancer risk in a cohort of 89,918 postmenopausal women participating in the WHI. A detailed …