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Honors Thesis

Immunity

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Full-Text Articles in Medicine and Health Sciences

Testing For Transferred Immunity Of A Universal Influenza Vaccine In Pigs, Rachel Marie Sestak Apr 2022

Testing For Transferred Immunity Of A Universal Influenza Vaccine In Pigs, Rachel Marie Sestak

Honors Thesis

Influenza causes high numbers of illnesses and deaths annually (CDC, 2020). Influenza vaccines prevent these complications by reducing the risk of flu illness between 40-60% (CDC, 2021). However, no vaccination exists for infants under six months old so other methods, such as passive immunity, must be explored. To determine how infants can be protected, we tested the passive transfer of a universal influenza vaccine using a pig model and researched the mechanism of transfer. Four pregnant pigs were vaccinated one time with PBS and one time with HA-129 vaccine and four were vaccinated twice with the HA-129 vaccine. After farrowing, …


Testing For Transferred Immunity Of A Universal Influenza Vaccine In Pigs, Rachel Marie Sestak Apr 2022

Testing For Transferred Immunity Of A Universal Influenza Vaccine In Pigs, Rachel Marie Sestak

Honors Thesis

Influenza causes high numbers of illnesses and deaths annually (CDC, 2020). Influenza vaccines prevent these complications by reducing the risk of flu illness between 40-60% (CDC, 2021). However, no vaccination exists for infants under six months old so other methods, such as passive immunity, must be explored. To determine how infants can be protected, we tested the passive transfer of a universal influenza vaccine using a pig model and researched the mechanism of transfer. Four pregnant pigs were vaccinated one time with PBS and one time with HA-129 vaccine and four were vaccinated twice with the HA-129 vaccine. After farrowing, …