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Full-Text Articles in Medicine and Health Sciences
The Lasting Effects Of Covid-19 On The Progression Of Metabolic Dysfunction-Associated Steatotic Liver Disease, Sean Backer, Deepesh Khanna
The Lasting Effects Of Covid-19 On The Progression Of Metabolic Dysfunction-Associated Steatotic Liver Disease, Sean Backer, Deepesh Khanna
HPD Articles
It is estimated that around 30% of the population living in Western countries has metabolic dysfunctionassociated steatotic liver disease (MASLD), a spectrum of pathology (not attributed to alcohol/substance intake) initiated by steatosis and progression toward inflammation and irreversible fibrosis metabolic dysfunction-associated steatohepatitis (MASH). With inflammation being a key component of the transition to MASH, it raises the question of whether the ongoing COVID-19 pandemic, which has notoriously induced hyperinflammatory states, may influence the progression of MASLD. Specifically, it remains unclear if the potential chronic sequelae of COVID-19 in patients who recovered from it may increase the predisposition for MASH. Since …
Severe Covid-19 Infection In An Infant With 8p Inverted Duplication/Deletion Syndrome: Is Vaccination Still A Debate?, Andrew M. Joseph, Monica Karas, Ernesto Joubran, Yaseen O. Ramadan, Blakley A. Fowler
Severe Covid-19 Infection In An Infant With 8p Inverted Duplication/Deletion Syndrome: Is Vaccination Still A Debate?, Andrew M. Joseph, Monica Karas, Ernesto Joubran, Yaseen O. Ramadan, Blakley A. Fowler
HPD Articles
Despite having a milder course of coronavirus disease 2019 (COVID-19) in comparison to adults, children are at risk for more significant complications, including acute neurological, renal, respiratory, and cardiovascular complications. Acute complications can manifest as encephalopathy, renal injury, interstitial pneumonia, and heart failure. However, the most severe complication is multisystem inflammatory syndrome in children, which often requires intensive care to manage the subsequent respiratory failure. Moreover, children with comorbidities such as chronic lung disease, neurological disorders, and cardiovascular disease are at an elevated risk of morbidity and mortality. Here, we present the case of an 11- month-old white female patient, …
Development Of Islet Antigen 2 (Ia2) Antibodies Post-Covid-19 Infection: A Sign Of Autoimmunity Or Latent Autoimmune Diabetes Mellitus In Adults (Lada)?, Nick Lee, Praveen Prabhu, Samyukta Swaminath, Sahar S. Amini
Development Of Islet Antigen 2 (Ia2) Antibodies Post-Covid-19 Infection: A Sign Of Autoimmunity Or Latent Autoimmune Diabetes Mellitus In Adults (Lada)?, Nick Lee, Praveen Prabhu, Samyukta Swaminath, Sahar S. Amini
HPD Articles
Further antibody tests and laboratory studies showed that the patient met the criteria for latent autoimmune diabetes in adults (LADA). In this case report, we will review the diagnostic workup and management of LADA in an individual following his COVID-19 infection.
A Scoping Review On The Effects Of Covid-19 On Syringe Service Programs In The United States., Dylan Pietrantoni, Crystal Barroca, Sarah Lynch, Jonathan Byrne, Miranda Ortner, Roshni Kotwani, Kolin Limbrick, Paul Kaldas, Michael Moussa, Tatem Fredrickson, Jeffrey Schaefer, Robin J. Jacobs
A Scoping Review On The Effects Of Covid-19 On Syringe Service Programs In The United States., Dylan Pietrantoni, Crystal Barroca, Sarah Lynch, Jonathan Byrne, Miranda Ortner, Roshni Kotwani, Kolin Limbrick, Paul Kaldas, Michael Moussa, Tatem Fredrickson, Jeffrey Schaefer, Robin J. Jacobs
HPD Articles
The COVID-19 pandemic has had worldwide impacts, including disrupting community services. One interrupted service was syringe service programs (SSPs), community-established initiatives that provide sterile supplies and aid in overcoming addiction in drug-using participants. In the United States (U.S.), SSPs have been key in combating the recent opioid use crisis and associated infections such as the human immunodeficiency virus (HIV) and hepatitis C. While some published reports on the pandemic's overall impacts on SSPs exist, certain aspects such as operational changes and repercussions on staff and participants may still be lacking. Information about the impact of interrupted SSP services due to …
Ventricular Fibrillation In An Afebrile Covid-19 Patient Presenting With Transient Type-I Brugada Pattern., Judah A. Kreinbrook, Annalia Foster, Luis Paulino, Fabio Leonelli
Ventricular Fibrillation In An Afebrile Covid-19 Patient Presenting With Transient Type-I Brugada Pattern., Judah A. Kreinbrook, Annalia Foster, Luis Paulino, Fabio Leonelli
HPD Articles
COVID-19 has been associated with an increased risk of both atrial and ventricular arrhythmias. Brugada syndrome (BrS), an inherited sodium channelopathy presenting with a characteristic ECG morphology, confers a baseline risk of ventricular arrhythmias such as ventricular fibrillation (VF), especially during febrile illnesses. However, mimics of BrS, termed Brugada phenocopies (BrP), have been noted in association with fever, electrolyte abnormalities, and toxidromes outside of viral illness. Such presentations manifest the same ECG pattern, the type-I Brugada pattern (type-I BP). Thus, the acute stage of an illness such as COVID-19, when accompanied by a first-time presentation of type-I BP, may not …
Transient Premature Ovarian Insufficiency Post-Covid-19 Infection., Colleen N. Gorman, Tori E. Abdalla, Yasmina Sultan, Spencer A. Grabois, Ellen G. Wood
Transient Premature Ovarian Insufficiency Post-Covid-19 Infection., Colleen N. Gorman, Tori E. Abdalla, Yasmina Sultan, Spencer A. Grabois, Ellen G. Wood
HPD Articles
Anti-ovarian antibodies (AOAs) have been linked to autoimmune premature ovarian insufficiency (POI). This report details a case in which a patient experienced transient POI after a COVID-19 infection and tested positive for AOA. After treatment with oral contraceptives and subsequent high-dose oral corticosteroids, the patient underwent fertility treatment with in vitro fertilization (IVF). A total of 23 oocytes were retrieved. Two euploid blastocysts and three untested blastocysts were successfully created. This report hypothesizes the connection between autoimmune POI, AOA, and COVID-19. Conflicting data have been reported linking COVID-19 and ovarian injury. However, it is suggested that COVID-19 transiently impacts the …
Avascular Necrosis As A Sequela Of Covid-19: A Case Series., Sarthak Parikh, Osmanny Gomez, Ty Davis, Zachary Lyon, Arturo Corces
Avascular Necrosis As A Sequela Of Covid-19: A Case Series., Sarthak Parikh, Osmanny Gomez, Ty Davis, Zachary Lyon, Arturo Corces
HPD Articles
Avascular necrosis (AVN) is a degenerative bone condition characterized by cellular death and bone collapse from compromised subchondral blood circulation. AVN begins with vascular interruption, hypertension, intravascular occlusion, or extravascular compression which reduces bone circulation. Although corticosteroids are frequently used to treat acute COVID-19 infections, patients are prone to its side effects, particularly AVN. Furthermore, COVID-19 produces coagulopathies, specifically hypercoagulability, that may contribute to venous thrombosis, which may serve as the impetus of AVN. While the literature discussing COVID-19, AVN, and corticosteroid use is not conclusive, patients being treated with corticosteroids for COVID-19 are at an increased risk for AVN …
A Case Of Transverse Myelitis Secondary To Covid-19 Infection, Rahul Borra, Neal T. Patel, Raheel Shaikh, Mayur S. Parmar, Sujatha Borra
A Case Of Transverse Myelitis Secondary To Covid-19 Infection, Rahul Borra, Neal T. Patel, Raheel Shaikh, Mayur S. Parmar, Sujatha Borra
HPD Articles
Infection with COVID-19 (SARS-CoV-2) is associated with a variety of generalized and specific symptoms, including neurological complications of both the peripheral and central nervous systems. In this case report, we present the case of a previously healthy 55-year-old woman who was diagnosed with transverse myelitis following a previous infection with COVID-19. MRI showed progressive demyelination of the cervical and thoracic spinal cord, and cerebrospinal fluid (CSF) showed increased levels of protein and red blood cells and no markers of infection, including negative polymerase chain reaction (PCR) for COVID-19 antibodies. The patient was treated with a course of methylprednisolone, multiple treatments …
A Review Of Covid-19 In Relation To Metabolic Syndrome: Obesity, Hypertension, Diabetes, And Dyslipidemia, Elias Makhoul, Joseph L. Aklinski, Jesse Miller, Cara Leonard, Sean Backer, Payal Kahar, Mayur S. Parmar, Deepesh Khanna
A Review Of Covid-19 In Relation To Metabolic Syndrome: Obesity, Hypertension, Diabetes, And Dyslipidemia, Elias Makhoul, Joseph L. Aklinski, Jesse Miller, Cara Leonard, Sean Backer, Payal Kahar, Mayur S. Parmar, Deepesh Khanna
HPD Articles
Although severe cases and mortality of coronavirus disease 2019 (COVID-19) are proportionally infrequent, these cases are strongly linked to patients with conditions of metabolic syndrome (obesity, hypertension, diabetes, and dyslipidemia). However, the pathophysiology of COVID-19 in relation to metabolic syndrome is not well understood. Thus, the goal of this secondary literature review was to examine the relationship between severe acute respiratory syndrome (SARS-CoV-2) infection and the individual conditions of metabolic syndrome. The objective of this secondary literature review was achieved by examining primary studies, case studies, and other secondary studies, to obtain a comprehensive perspective of theories and observations of …