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Full-Text Articles in Medicine and Health Sciences
A Prelimary Study Of Differences Between Voluntary And Involuntary Retirement From Driving: Quality Of Life And Depression In A Rural Population, Elizabeth Ann Pruitt Saxton
A Prelimary Study Of Differences Between Voluntary And Involuntary Retirement From Driving: Quality Of Life And Depression In A Rural Population, Elizabeth Ann Pruitt Saxton
Graduate College Dissertations and Theses
Research has revealed a variety of negative health consequences for older adults who stop driving, and with the "graying of America," this will be a frequently encountered issue for healthcare providers. The purpose of this study was to determine if there are differences in quality of life and depressive symptoms between former drivers who made the decision to stop driving voluntarily and former drivers who made the decision involuntarily (either in a resistant or in a reluctant manner). In this cross-sectional cohort comparison study, community dwelling older adults were asked to complete questionnaires of depression (using the Geriatric Depression Scale), …
Glycogen Synthase Kinase-3Β: An Investigation Of The Novel Serine 389 Phosphorylation Site, Brendan Deegan Hare
Glycogen Synthase Kinase-3Β: An Investigation Of The Novel Serine 389 Phosphorylation Site, Brendan Deegan Hare
Graduate College Dissertations and Theses
Stress associated psychiatric disorders such as depression, anxiety, and post-traumatic stress disorder affect a large proportion of the population. Reductions in the complexity of neuronal morphology and reduced neurogenesis are commonly observed outcomes following stress exposure in rodent models and may represent a mechanism for the reduced brain volume in stress sensitive regions such as the hippocampus observed in individuals diagnosed with stress associated disorders. Multiple lines of evidence suggest that glycogen synthase kinase (GSK)-B may play a role in the neurodegenerative phenotype observed following stress exposure. GSK3B is atypical in that it is inhibited by phosphorylation. This inhibitory phosphorylation …