Medicine and Health Sciences Commons^™

Effects Of Ultraviolet Radiation And Visible Light On The Development Of Encapsulated Molluscan Embryos, Rachel Przeslawski, Andrew R. Davis, Kirsten Benkendorff

Faculty of Science, Medicine and Health - Papers: part A

Benthic egg masses laid in intertidal habitats are exposed to numerous environmental stresses including potentially damaging ultraviolet radiation (UVR). We sought to determine the developmental effects of UVR and visible light on molluscan embryos within egg masses from habitats with differential UVR exposure. Capsular and gelatinous egg masses from 23 marine gastropod species were collected from 3 intertidal habitats: (1) full sun, (2) partial shade, and (3) full shade. Egg masses were then divided among 4 spectral treatments: full spectrum, no UV-B, no UV, and dark. An ANOVA confirmed that a significant interaction between original habitat and spectral treatment affected …

Effects Of Dexamethasone On Posterior Capsule Opacification-Like Changes In A Rat Lens Explant Model, Kylie Mansfield, Anna Cerra, Coral Chamberlain

Faculty of Science, Medicine and Health - Papers: part A

Purpose: Many patients whose sight is initially restored by cataract surgery eventually suffer secondary loss of vision because of posterior capsule opacification (PCO; after-cataract), a condition in which lens epithelial cells left behind at surgery become aberrant and migrate into the light path. The aim of this study was to determine whether dexamethasone (DEX), an anti-inflammatory agent widely used before and after cataract surgery, influences the behavior of lens cells under conditions relevant to PCO development.

Methods: An established rat PCO model was used in which explanted epithelial cells attached to the lens capsule are exposed sequentially to TGFβ2 and …