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Trace Metal Exposure Is Associated With Increased Exhaled Nitric Oxide In Asthmatic Children, Krystal J. Godri Pollitt, Caitlin L. Maikawa, Amanda J. Wheeler, Scott Weichenthal, Nina A. Dobbin, Ling Liu, Mark S. Goldberg
Trace Metal Exposure Is Associated With Increased Exhaled Nitric Oxide In Asthmatic Children, Krystal J. Godri Pollitt, Caitlin L. Maikawa, Amanda J. Wheeler, Scott Weichenthal, Nina A. Dobbin, Ling Liu, Mark S. Goldberg
Environmental Health Sciences Faculty Publication Series
Background
Children with asthma experience increased susceptibility to airborne pollutants. Exposure to traffic and industrial activity have been positively associated with exacerbation of symptoms as well as emergency room visits and hospitalisations. The effect of trace metals contained in fine particulate matter (aerodynamic diameter 2.5 μm and lower, PM2.5) on acute health effects amongst asthmatic children has not been well investigated. The objective of this panel study in asthmatic children was to determine the association between personal daily exposure to ambient trace metals and airway inflammation, as measured by fractional exhaled nitric oxide (FeNO).
Methods
Daily concentrations of trace metals …