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Articles 1 - 22 of 22
Full-Text Articles in Medicine and Health Sciences
Perceived Barriers To The Teaching Of Critical Thinking Skills By Nursing Faculty In Generic Bsn Programs In Tennessee, Renee C. Shell
Perceived Barriers To The Teaching Of Critical Thinking Skills By Nursing Faculty In Generic Bsn Programs In Tennessee, Renee C. Shell
Electronic Theses and Dissertations
Teaching critical thinking is a national education goal. The ability to think critically is considered an essential skill of nursing graduates and is a necessary component of competent nursing practice. Therefore, nursing programs must address critical thinking for accreditation. The literature reports that teachers in all areas of education are having difficulties infusing critical thinking teaching strategies into their current teaching practices and critical thinking is lacking in new nursing graduates. This research study sought to identify barriers to the implementation of critical thinking teaching strategies as perceived by nursing faculty in generic, BSN programs in Tennessee. Data were collected …
Signaling Mechanisms For Muscarinic Receptor-Mediated Coronary Vasoconstriction In Isolated Rat Hearts, Yi Zhang
Electronic Theses and Dissertations
The signaling mechanisms for muscarinic receptor-mediated vasoconstriction in coronary resistance arteries were studied in KCl-arrested isolated rat hearts perfused at a constant flow rate. The cholinergic agonists acetylcholine and bethanechol were given by bolus injection or constant infusion. The coronary vascular resistance was monitored by measuring the changes in perfusion pressure. The selective muscarinic agonist bethanechol caused a similar vasoconstrictor response as ACh, but with less potency and efficacy. Bolus injection of bethanechol evoked a phasic vasoconstriction in a dose-dependent manner, while infusion of bethanechol evoked a tonic vasoconstriction without producing tachyphylaxis. Coronary vascular responses to bethanechol were further examined …
Identifying The Behavior, Attitudes, And Knowledge Of Tobacco Use Among Students Enrolled In Orientation Courses In Six Community Colleges In The Tennessee Board Of Regents System, G. E. Boone
Electronic Theses and Dissertations
The purpose of this study was to examine the behavior, attitudes, and knowledge regarding tobacco use of students enrolled in orientation courses in Tennessee community colleges. The six community colleges selected for the study were members of the Tennessee Board of Regents system that offered mandatory orientation courses. Data were collected by use of the College Tobacco Behavior, Attitude, and Knowledge Survey . A response rate of (72.5%) from 700 students was analyzed. Three research questions guided the study and 17 null hypotheses were formulated and tested at the.05 alpha level of significance. Data were analyzed by using t -tests, …
Entry-Level Competencies Needed By Bsns In Acute Healthcare Agencies In Tennessee In The Next Ten Years, Marjorie S. King
Entry-Level Competencies Needed By Bsns In Acute Healthcare Agencies In Tennessee In The Next Ten Years, Marjorie S. King
Electronic Theses and Dissertations
The research focused on the identification of entry-level competencies needed by Bachelor of Science in Nursing (BSN) graduates who will begin employment in acute healthcare agencies in the next 10 years in Tennessee. The purpose of the study was to gain increased awareness of the competencies needed by graduates of BSN programs in Tennessee in order to meet the demands of the acute healthcare agencies, in light of present and anticipated changes in the healthcare delivery system. The opinions of nurse educators, nurse administrators, recently graduated BSNs, and experienced BSN graduates were solicited to assess congruency of perceptions. In addition, …
The Nature, Scope, And Consequences Of Drug And Alcohol Use Of Students Enrolled At Three Southern Appalachian Community Colleges, Jewel D. Morgan
The Nature, Scope, And Consequences Of Drug And Alcohol Use Of Students Enrolled At Three Southern Appalachian Community Colleges, Jewel D. Morgan
Electronic Theses and Dissertations
The primary purpose of this study was to determine the nature, scope, and consequences of drug and alcohol use by students enrolled at three southern Appalachian community colleges: Mountain Empire Community College (MECC) in Virginia, Northeast State Technical Community College (NSTCC) in Tennessee, and Southwestern Community College (SCC) in North Carolina. An additional purpose was to use this information to formulate recommendations for new and improved preventive substance-abuse programs. The design for this study was descriptive research. The Core Alcohol and Drug Survey (CORE) was selected as the appropriate instrument for use in this study. The 23-item questionnaire was designed …
In Vitro Assessment Of The Toxicity Of Cocaine And Its Metabolites In The Human Umbilical Artery, Tessa L. Long
In Vitro Assessment Of The Toxicity Of Cocaine And Its Metabolites In The Human Umbilical Artery, Tessa L. Long
Electronic Theses and Dissertations
An in vitro model was used to assess the effect of cocaine and its metabolites on the umbilical artery. Objectives were to pharmacologically confirm the presence of adrenergic innervation using tyramine, evaluate the ability of cocaine, benzoylecgonine, norcocaine and cocaethylene to potentiate vasoconstriction by serotonin and norepinephrine, examine the ability of ketanserin to block the enhanced vasoconstriction produced by cocaine, and determine displacement of 3 H-ketanserin by serotonin, norepinephrine, tyramine and mianserin. The vasoconstrictive effect of tyramine (100 μM) was enhanced in the presence of cocaine by 257%. Vasoconstrictive effects of serotonin and norepinephrine were significantly enhanced by cocaine by …
Collegiate Activities That Influence Adult Physical Fitness Habits, Linda L. King
Collegiate Activities That Influence Adult Physical Fitness Habits, Linda L. King
Electronic Theses and Dissertations
This descriptive/correlational study analyzed the perception of recent graduates regarding the effectiveness of the college environment at Milligan College in influencing adult fitness habits. Graduates were divided into five activity level groups through a self-report of physical activity. The purposes of the research were to determine if significant differences existed between the dependent variable, activity level, and the independent variables such as: (a) participation in specific college activities, (b) preferences for types of exercise, (c) social influence, (d) influence of a required freshman fitness course, and (e) environmental barriers. A profile of the student most likely to exercise after graduation …
Comparison Of Beta-Adrenoceptor Coupled Camp Production In Cultured Human Mononuclear Leukocytes And Myometrial Cells, Yu-Li Liu
Electronic Theses and Dissertations
$\beta\sb2$-Adrenoceptor ($\beta\sb2$-AR) agonists, such as terbutaline, are used as tocolytic agents in the treatment of preterm labor. $\beta$-Adrenoceptor stimulation relaxes myometrium through specific receptors coupled through Gs to adenylyl cyclase (AC) that catalyzes the conversion of ATP to cAMP. The purpose of this study was to compare $\beta$-adrenoceptors and cAMP production in cultured human leukocytes and myometrial cells, and to determine the importance of $\beta$-adrenoceptors and cAMP production in isoproterenol-induced myometrial relaxation. $\sp{125}$I-iodopindolol was used to assess $\beta$-adrenoceptor affinity and number cAMP levels were analyzed before and after stimulation by isoproterenol, AlF$\sb4\sp-$, forskolin, and PGE$\sb1$. Isometric recording was used to …
A Case Study Of An Elementary School-Based Health Clinic, Sheila K. Jones
A Case Study Of An Elementary School-Based Health Clinic, Sheila K. Jones
Electronic Theses and Dissertations
The purpose of this study was to perform a qualitative analysis of an elementary school-based health clinic (SBHC). This situational analysis was performed to further understand the impact of accessible primary health care on an elementary school population. Data were collected through 30 participant interviews of parents, educators and medical personnel. Additional data were collected through the clinic files, and a t-test was used to compare the attendance and achievement data of clinic consumers for the clinic year against records from the previous year. The researcher presented information on the steps of SBHC development to include community campaign procedures. The …
Southern Appalachian Settlement Schools As Early Initiators Of Integrated Services, Eloise H. Jurgens
Southern Appalachian Settlement Schools As Early Initiators Of Integrated Services, Eloise H. Jurgens
Electronic Theses and Dissertations
This historical-descriptive study examined Southern Appalachian settlement schools as early initiators of integrated health and social services with education from the 1900s through the 1970s. Three schools were studied: Hindman Settlement School (KY), Pine Mountain Settlement School (KY) and Crossnore School, Inc. (NC). The purpose of the study was to determine the type and extent of services provided, the relationship of the settlement schools with their respective county public school system, and the transfer, if any, of integrated services from the settlement schools to public schools as the public schools took over educational responsibilities once offered by the settlement schools. …
Moraxella (Branhamella) Catarrhalis: A Molecular Epidemiology Study, Lyndell R. Gill
Moraxella (Branhamella) Catarrhalis: A Molecular Epidemiology Study, Lyndell R. Gill
Electronic Theses and Dissertations
Moraxella (Branhamella) catarrhalis is the third-most-frequently isolated microorganism associated with acute exacerbations of chronic bronchitis in patients during their stay at the Mountain Home VA Medical Center (MHVAMC). In order to develop a practical, epidemiologically-meaningful typing method for M. (B.) catarrhalis, we tested two methods based on analysis of chromosomal DNA for typeability, reproducibility, and ability to differentiate between unrelated strains (discriminatory power, D). M. (B.) catarrhalis isolants from MHVAMC from 7/1/87-6/30/88 were grown overnight in broth and embedded in agarose. DNA was isolated by standard methods. The DNA was subjected to: (1) restriction endonuclease digestion (with either Bgl II …
Persistent Oral Dyskinesias Induced By Long-Term Haloperidol Treatment Is Dissociated From Changes In Neostriatal B(Max) And Mrna Content For Dopamine D(2) Receptors, Nuoyu Huang
Electronic Theses and Dissertations
Due to the presumed associations of dopamine (DA) receptor supersensitivity phenomena in both long-term neuroleptic-treated tardive dyskinetic rats and neonatal 6-hydroxydopamine (n6-OHDA)-lesioned rats, we studied the influence of haloperidol on n6-OHDA-lesioned rats. At 3 days after birth rats received 6-OHDA-HBr (200 $\mu$g, bilateral intracerebroventricularly; desipramine pretreatment, 20 mg/kg, 1h) or vehicle. Two months later haloperidol (1.5/kg/day $\times$ 2 days/week for 4 weeks, then 1.5 mg/kg/day, every day for 10 months) was added to the drinking water. Spontaneous oral activity of intact and n6-OHDA-lesioned rats receiving haloperidol was reached and maintained at significantly higher levels after 15 weeks of haloperidol treatment. …
Indomethacin Reduces Splenic Red Pulp Macrophage Populations In Female New Zealand White Rabbits, Thane S. Thurmond
Indomethacin Reduces Splenic Red Pulp Macrophage Populations In Female New Zealand White Rabbits, Thane S. Thurmond
Electronic Theses and Dissertations
In an effort to elucidate the mechanism by which indomethacin (IN) attenuates the stimulatory effect of estradiol (E$\sb2$) on rabbit splenic red pulp macrophages (RPM), thirty-nine female New Zealand White rabbits were divided into 10 groups: ovariectomized (OVX), OVX/IN at 0.1 and 5.0 mg/kg body weight (bw)/day; sham OVX (SOVX), SOVX/IN at 0.1 and 5.0 mg/kg bw/day; OVX/25 mg E2, OVX/25 mg E$\sb2$/IN at 0.1 and 5.0 mg/kg bw/day; intact Control. Quantitative changes in RPM population in response to the treatments were measured using a 0 to 4 histologic grading scale. Estradiol treatment resulted in increased RPM grade when compared …
Denervation Supersensitivity Of The Rat Vas Deferens: A Role For Protein Kinase C, Sonny T. Abraham
Denervation Supersensitivity Of The Rat Vas Deferens: A Role For Protein Kinase C, Sonny T. Abraham
Electronic Theses and Dissertations
A role for protein kinase C (PKC) in the denervation-induced supersensitivity of the rat vas deferens was investigated. Chronic, surgical denervation of the rat vas deferens (up to 8 days) resulted in tissues that produced enhanced contractile responses to norepinephrine (NE) in isolated organ baths. Single challenges of NE (10 $\mu$M) produced 0.6 $\pm$ 0.1 g of maximal tension in the control vas whereas in the paired, denervated tissue 2.2 $\pm$ 0.3 g of tension was recorded (n = 6). Cumulative concentration-effect curves to NE produced in the denervated vas deferens were shifted 18-fold to the left of the control …
Differential Role Of The Endothelium In Regulating Microvascular Blood Flow, Tao Tang
Differential Role Of The Endothelium In Regulating Microvascular Blood Flow, Tao Tang
Electronic Theses and Dissertations
The vascular endothelial cell (EC) plays an important role in regulating vascular tone and local blood flow by sensing chemical and mechanical stimuli on the vascular wall and releasing a host of vasoactive substances upon activations of endogenous or exogenous vasoactive substances. The central hypothesis is that local control of blood now and autoregulatory behavior in the microcirculation is distinctive at different levels of the vasculature and is dependent on the cellular activities of the EC and its interaction with the local environment. The in vivo as well as the ex vivo, flow-controlled preparations of the hamster cheek pouch were …
Characterization Of The Vasoactivity Of Tachykinins In Isolated Rat Kidney: Functional Studies And In Vitro Receptor Autoradiography, Yuejin Chen
Electronic Theses and Dissertations
Although tachykinins have potent vascular actions, their effect on renal resistance blood vessels is currently unknown. The vasoactive properties of tachykinins and related analogs were assessed in isolated perfused rat kidney. At a basal perfusion pressure (PP) of 75 $\pm$ 6 mm Hg (n = 5), bolus injections of substance P (SP) had no significant vasoactive effect. Following a sustained increase in baseline PP (134 $\pm$ 10 mm Hg) produced by phenylephrine (1 $\mu$M), SP evoked a dose-dependent increase in PP. The largest dose of SP increased PP by 60 $\pm$ 5 mm Hg. The vasoconstrictor response to SP was …
Co-Sensitization Of Dopamine And Serotonin Receptors Occurs In The Absence Of A Change In The Dopamine D1 Receptor Complex After A Neonatal 6-Ohda Lesion, Li Gong
Electronic Theses and Dissertations
To test whether SKF 38393 could ontogenetically sensitize dopamine (DA) D$\sb1$ receptors and whether this sensitization would be associated with biochemical changes, intact and neonatal 6-hydroxydopamine (6-OHDA)-lesioned rats (200 $\mu$g i.c.v.) were treated daily from birth with SKF 38393 (3.0 mg/kg i.p. x 28 days) or its vehicle. In DA D$\sb1$ neonatally sensitized 6-OHDA rats, enhanced locomotor responses were observed with the first SKF 38393 challenge dose (3.0 mg/kg i.p.) at 6 weeks. This response increased further with weekly SKF 38393 treatments. Enhanced stereotyped behaviors were seen in both lesioned and sensitized rats at 8 weeks. There was no change …
The Effect Of Trimethyltin On The Cholinergic System Of The Rat Hippocampus, Richard L. Cannon
The Effect Of Trimethyltin On The Cholinergic System Of The Rat Hippocampus, Richard L. Cannon
Electronic Theses and Dissertations
Trimethyltin (TMT) is a neurotoxin occurring in the environment. Exposure to (TMT) is known to destroy specific neuronal components of the hippocampus in the rat and to cause clinical symptoms in exposed humans, including mnemonic deficits, that indicate hippocampal involvement. In addition to hippocampal cell loss TMT causes significant increases in cholinergic markers such as acetylcholinesterase (AChE) stain density and choline acetyltransferase (ChAT) activity in the hippocampus of rats. However, despite these observations the effect of TMT on hippocampal cholinergic system has not been investigated in detail. The purpose of the present study was to elucidate more fully the consequences …
Occupational Stress Among Nurse Administrators In General Hospitals In Tennessee, Ruby T. Davis
Occupational Stress Among Nurse Administrators In General Hospitals In Tennessee, Ruby T. Davis
Electronic Theses and Dissertations
The purpose of this study was to determine the level of occupational stress among nurse administrators and to identify the types of strategies used by nurse administrators to deal with or manage occupational stress. The study examined the relationship between selected demographic variables, occupational stress, and strategies. The research design included five research questions along with seven null hypotheses testing the relationship between occupational stress and demographic variables--age, gender, marital status, years of professional nursing experience, years as a nurse administrator, educational attainment, and hospital bed capacity. There were seven additional hypotheses testing the relationship between the same demographic variables …
Molecular And Cellular Analysis Of Chlamydia Trachomatis: Persistence And Reactivation, Kimberly R. Tau
Molecular And Cellular Analysis Of Chlamydia Trachomatis: Persistence And Reactivation, Kimberly R. Tau
Electronic Theses and Dissertations
Chlamydia trachomatis (CT) is the most prevalent sexually-transmitted infection in the United States. It has been suggested that CT infections can become latent. This has not been substantiated. CT persistence was examined at the molecular and cellular level in vitro and in vivo. Penicillin treatment of CT in vitro results in abnormal inclusions and reduced recovery of infectious CT. Penicillin did not inhibit initial stages of infection, but did downregulate CT rRNA levels after 25 hours post-inoculation (p.i.). DNA amplification was employed to differentiate between a resolved infection and a persistent one. Utilizing a primer pair that amplified a 144 …
A Comparative Analysis Of Registered Nurse Demand In Tennessee Rural And Urban Hospitals And Nursing Homes, Carol H. Pullen
A Comparative Analysis Of Registered Nurse Demand In Tennessee Rural And Urban Hospitals And Nursing Homes, Carol H. Pullen
Electronic Theses and Dissertations
The purpose of this study was to compare Registered Nurse (RN) current and future demand between Tennessee rural and urban licensed hospitals and nursing homes. Comparisons of Registered Nurse demand by principal duty or position and by educational level were also undertaken. The educational level of RNs was examined using the proportion of RNs at each of five educational levels: diploma, associate, baccalaureate, master's, and doctorate. The variables examined were 1988 and 1989 vacancy rates and proportion of budgeted positions, change in vacancy rates and proportions from 1988 to 1989, projected changes in positions and proportions from 1988 to 1992 …
Beliefs Concerning Role Of The Nursing Service Administrator In Hospitals As Expressed By Chief Executive Officers, Nursing Service Administrators, And Nurse Educators, Jimmie R. Williams
Beliefs Concerning Role Of The Nursing Service Administrator In Hospitals As Expressed By Chief Executive Officers, Nursing Service Administrators, And Nurse Educators, Jimmie R. Williams
Electronic Theses and Dissertations
This study was undertaken to determine the degree of relationship in perceptions held by three health care administrative groups between the desirable and actual role functions of the hospital nursing service administrator. This descriptive study surveyed hospital Chief Executive Officers (CEOs), and Nursing Service Administrators (NSAs) in 100 randomly selected general hospitals, and chairpersons of graduate programs in nursing service administration. The instrument for this study was the Beliefs Concerning Role of Hospital Nursing Service Administrator, a 12-item instrument designed to determine some of the desirable (optimal) and actual (currently performed) role functions of the hospital Nursing Service Administrator (NSA), …