Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Community Health and Preventive Medicine (2)
- Medical Sciences (2)
- Medicinal Chemistry and Pharmaceutics (2)
- Pharmacology, Toxicology and Environmental Health (2)
- Public Health (2)
-
- Agriculture (1)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (1)
- Animal Sciences (1)
- Biochemistry (1)
- Biochemistry, Biophysics, and Structural Biology (1)
- Biomedical Engineering and Bioengineering (1)
- Biotechnology (1)
- Engineering (1)
- Environmental Health (1)
- Environmental Public Health (1)
- Genetics (1)
- Genetics and Genomics (1)
- Genomics (1)
- Health Services Research (1)
- Immunity (1)
- Immunology and Infectious Disease (1)
- Immunology of Infectious Disease (1)
- Immunopathology (1)
- Immunoprophylaxis and Therapy (1)
- Infectious Disease (1)
- International Public Health (1)
- Large or Food Animal and Equine Medicine (1)
- Keyword
-
- ACT (1)
- AIDS (1)
- Antibiotic feed (1)
- Antibiotic resistance (1)
- Antibiotic use (1)
-
- Antibiotics (1)
- Bacteria (1)
- CRISPR (1)
- CRISPR/Cas9 (1)
- Cancer (1)
- Cas9 (1)
- Cas9/gRNA (1)
- Gene editing (1)
- Gene therapy (1)
- Genetic engineering (1)
- HAART (1)
- HIV (1)
- HIV-1 (1)
- Immunotherapy (1)
- Infectious diseases (1)
- Livestock (1)
- Pandemic (1)
- Recombinant DNA (1)
- Retrovirus (1)
- T-cell (1)
- Transmission (1)
- Transmission of antibiotic resistance (1)
- Vaccine (1)
Articles 1 - 3 of 3
Full-Text Articles in Medicine and Health Sciences
Hiv Vaccines: Progress, Limitations And A Crispr/Cas9 Vaccine, Omar A. Garcia Martinez
Hiv Vaccines: Progress, Limitations And A Crispr/Cas9 Vaccine, Omar A. Garcia Martinez
Biology: Student Scholarship & Creative Works
ABSTRACT: The HIV-1 pandemic continues to thrive due to ineffective HIV-1 vaccines. Historically, the world’s most infectious diseases, such as polio and smallpox, have been eradicated or have come close to eradication due to the advent of effective vaccines. Highly active antiretroviral therapy is able to delay the onset of AIDS but can neither rid the body of HIV-1 proviral DNA nor prevent further transmission. A prophylactic vaccine that prevents the various mechanisms HIV-1 has to evade and attack our immune system is needed to end the HIV-1 pandemic. Recent advances in engineered nuclease systems, like the CRISPR/Cas9 system, have …
Impacts From The Use Of Antibiotics In Livestock: Methods Of Transmission Of Antibiotic Resistance From Livestock To Humans, Kristin M. Walden
Impacts From The Use Of Antibiotics In Livestock: Methods Of Transmission Of Antibiotic Resistance From Livestock To Humans, Kristin M. Walden
Biology: Student Scholarship & Creative Works
Antibiotic use in livestock production has been around since the 1950s. Antibiotic feed is used in livestock and other meat producing animals for three reasons: illness prevention, illness treatment, and growth promotion. Unfortunately, since the time that antibiotics were first invented, antibiotic resistant bacteria have become a threat to public health. There are many studies showing methods of transmission of antibiotic resistance from livestock to humans. Antibiotic resistance can spread from livestock to soil, water, insects, and food, which ultimately comes into contact with humans. A proposed study to measure antibiotic resistance when eliminating antibiotic feed will provide a hypothesis …
Challenges Of Adoptive (T-)Cell Transfer Immunotherapy For Cancer, Aaron Volk
Challenges Of Adoptive (T-)Cell Transfer Immunotherapy For Cancer, Aaron Volk
Biology: Student Scholarship & Creative Works
Background and significance: The rebirth of the theory of immunosurveillance in 2001 rejuvenated interest in anticancer immunotherapies. In particular, T-cell-based therapies have garnered substantial interest due to the robustness and tumor antigen-specific cytotoxicity of T-cell anticancer immune responses.
Hypothesis: The efficacy of adoptive cell transfer (ACT) T-cell immunotherapy could significantly improve and gain widespread approval if future innovations in ACT-based approaches account for the pro- and antitumoral properties of non-CD8+ lineages of effector T-cells, evasion of T-cell antitumor immunity, and tumor-induced suppression of antitumor immunity.
Problem Analysis: Despite numerous reports of highly successful ACT-based clinical trials, no such therapy …