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Full-Text Articles in Medicine and Health Sciences
Conscientious Objection To Harmful Animal Use Within Veterinary And Other Biomedical Education, Andrew Knight
Conscientious Objection To Harmful Animal Use Within Veterinary And Other Biomedical Education, Andrew Knight
Andrew Knight, PhD
Laboratory classes in which animals are seriously harmed or killed, or which use cadavers or body parts from ethically debatable sources, are controversial within veterinary and other biomedical curricula. Along with the development of more humane teaching methods, this has increasingly led to objections to participation in harmful animal use. Such cases raise a host of issues of importance to universities, including those pertaining to curricular design and course accreditation, and compliance with applicable animal welfare and antidiscrimination legislation. Accordingly, after detailed investigation, some universities have implemented formal policies to guide faculty responses to such cases, and to ensure that …
Non-Animal Methodologies Within Biomedical Research And Toxicity Testing, Andrew Knight
Non-Animal Methodologies Within Biomedical Research And Toxicity Testing, Andrew Knight
Andrew Knight, PhD
Laboratory animal models are limited by scientific constraints on human applicability, and increasing regulatory restrictions, driven by social concerns. Reliance on laboratory animals also incurs marked – and in some cases, prohibitive – logistical challenges, within high-throughput chemical testing programmes, such as those currently underway within Europe and the US. However, a range of non-animal methodologies is available within biomedical research and toxicity testing. These include: mechanisms to enhance the sharing and assessment of existing data prior to conducting further studies, and physicochemical evaluation and computerised modelling, including the use of structure-activity relationships and expert systems. Minimally-sentient animals from lower …