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Medicine and Health Sciences Commons

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All ETDs from UAB

2023

Differentiation

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Full-Text Articles in Medicine and Health Sciences

Role Of Dpy30 In The Epigenetic Regulation Of Odontoblast Differentiation In Vitro, Namrate Landge Rana Jan 2023

Role Of Dpy30 In The Epigenetic Regulation Of Odontoblast Differentiation In Vitro, Namrate Landge Rana

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Purpose: Dentin is produced from odontoblasts, derived from human Dental Pulp Cells (hDPCs), which are essential for dentin formation, remodeling, and mineral hemostasis. Epigenetic mechanisms are believed to be involved in odontoblast differentiation and function, and H3K4 methylation is associated with gene activation which is fundamental to histone-based epigenetics. The SET1/MLL complexes are mammals' major histone H3K4 methylation enzymes. DPY30 is a core subunit of SET1/MII complexes, mammalian's major histone H3K4 methyltransferases. It plays an important role in regulating fundamental processes including the determination of cell lineage, growth, and differentiation. Thus, histone-based epigenetic mechanisms are involved in odontoblast differentiation and …


Advanced Applications Of Existing Technology And Their Influence On Quality Outcomes In Federally Qualified Health Centers, Ali Riza Demirbas Jan 2023

Advanced Applications Of Existing Technology And Their Influence On Quality Outcomes In Federally Qualified Health Centers, Ali Riza Demirbas

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Increasing competition in the healthcare industry is compelling organizations to adopt new strategies to obtain and/or maintain a competitive advantage. To obtain a competitive advantage, healthcare organizations may need either more efficient processes or offer new or improved products and services through the utilization of these strategies. In competitive market environments, technological innovations can be a key competitive advantage to reduce expenses, improve quality, attract more customers, or a combination of all. All healthcare organizations can benefit from technological innovations, especially those with limited resources. One type of healthcare organization that highlights the disparity in resources is the Federally Qualified …