Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

All ETDs from UAB

Theses/Dissertations

2012

Master of Science (MS) School of Optometry

Articles 1 - 3 of 3

Full-Text Articles in Medicine and Health Sciences

The Effect Of Structured Background On Smooth Pursuit With Real And Simulated Central Scotoma, Thomas Keith Jan 2012

The Effect Of Structured Background On Smooth Pursuit With Real And Simulated Central Scotoma, Thomas Keith

All ETDs from UAB

The purpose of the study was to better understand the role of the fovea in smooth pursuit eye movements in human subjects. The research entailed a systematical study of a previously unstudied condition where the foveal inputs of both the background and the pursuit target were eliminated through simulation but the anatomic fovea was intact; and a comprehensive study of smooth pursuit eye movements of human subjects with real central scotoma. Ten normally sighted subjects (NS) and three central scotoma subjects (CS) were asked to visually pursuit a 0.87o yellow dot moving along either a horizontal or a vertical trajectory …


Localization Of Proteins Involved In Trafficking In Frog And Mouse Retina, Amie Marsh Jan 2012

Localization Of Proteins Involved In Trafficking In Frog And Mouse Retina, Amie Marsh

All ETDs from UAB

The connecting cilium serves as the major route for protein transport from the inner to outer segment of photoreceptor cells. The hypothesis that all Congenital Stationary Night Blindness (CSNB) rhodopsin mutants travel properly to the rod outer segment in Xenopus laevis will be tested by preparing transgenic X. laevis expressing a rhodopsin mutation found in human CSNB, A295V. In addition, probing for the existence of potential proteins involved in regulating rhodopsin trafficking and monitoring their localization will contribute to a better understanding of the underlying pathway of intracellular photoreceptor trafficking.


The Effect Of A Topical Ocular Preparation On Performance Of Simulated Driving In Cases Of Symptomatic Dry Eye, Chandra Venise Mickles Jan 2012

The Effect Of A Topical Ocular Preparation On Performance Of Simulated Driving In Cases Of Symptomatic Dry Eye, Chandra Venise Mickles

All ETDs from UAB

Dry eye is a common complaint of millions of people worldwide with a significant impact on quality of life. In particular, it could have a significant impact on vision-related activities of daily living such as driving. The purpose of this investigation was to determine if 30 days of active topical dry eye treatment (Systane® Balance, Alcon Laboratories; Ft. Worth, TX) has an impact on the simulated night-time driving performance in mild or moderate dry eye compared to a topical saline (Sensitive Eyes®, Bausch & Lomb; Rochester NY). Dry eye symptoms and signs were also assessed to corroborate our findings. Forty …