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Wright State University

Master of Public Health Program Student Publications

2019

Cancer

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Perfluoroalkyl Substances Exposure And Cancer In Nhanes 2011-2016 U.S. Population, Michael Crowder Jan 2019

Perfluoroalkyl Substances Exposure And Cancer In Nhanes 2011-2016 U.S. Population, Michael Crowder

Master of Public Health Program Student Publications

Background: Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are persistent synthetic compounds that may have associated health risks.

Purpose: To explore the association between four common detectable serum PFASs perfluorooctanoic acid (PFOA), perfluorooctyl sulfonate (PFOS), perfluorohexane sulfonate (PFHxS), and perfluorononanoic acid (PFNA) and cancer risk in United States (U.S.) adults.

Methods: Data from 4,497 participants from the 2011–2016 National Health and Nutrition Examination Survey (NHANES) were analyzed. Gender stratified adjusted logistic regression analysis was conducted to determine association between serum PFASs tertiles and risk of cancer.

Results: Median (IQR) PFASs were significantly higher in men compared to women, and among individual with …