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Full-Text Articles in Medicine and Health Sciences
Moyamoya Syndrome In An Infant With Aicardi-Goutières And Williams Syndromes: A Case Report, Jagraj S. Brar, Rahul Verma, Mohammed Al-Omari, Victoria M. Siu, Andrea V. Andrade, Michael T. Jurkiewicz, Saptharishi Lalgudi Ganesan
Moyamoya Syndrome In An Infant With Aicardi-Goutières And Williams Syndromes: A Case Report, Jagraj S. Brar, Rahul Verma, Mohammed Al-Omari, Victoria M. Siu, Andrea V. Andrade, Michael T. Jurkiewicz, Saptharishi Lalgudi Ganesan
Paediatrics Publications
Stroke in infancy is a rare phenomenon but can lead to significant long-term disability. We present the story of a 6-month-old Old Order Amish infant with underlying Williams syndrome, a rare neurodevelopmental disorder caused by a microdeletion, encompassing the elastin gene that produces abnormalities in elastic fibers of the lungs and vessels. This infant presented with lethargy, irritability, and a new-onset generalized tonic-clonic seizure. Brain magnetic resonance imaging (MRI) was consistent with ischemic stroke in the supratentorial regions. MR angiogram demonstrated bilateral narrowing of the internal carotid arteries with ivy sign, suggestive of Moyamoya. Moyamoya disease/syndrome is a cerebrovascular condition …
Causes Of Post Stroke Falls Along The Care Continuum: Implications For Improving Patient Safety, Mona Madady
Causes Of Post Stroke Falls Along The Care Continuum: Implications For Improving Patient Safety, Mona Madady
Electronic Thesis and Dissertation Repository
In Western countries stroke is responsible for 10-12% of all deaths. In 2000, strokes cost $3.6 billion for the Canadian healthcare system and lost productivity due to premature death and long-term disability. Falls are a frequent occurrence at all stages of post-stroke recovery and can have significant negative impacts. While information about the incidence and risk factors of falling among stroke survivors is available, considerably less is known about the specific factors contributing to falls and the circumstances surrounding these adverse events. The purpose of this project was to identify similarities between systemic factors of falls in stroke survivors across …
The Effect Of Selective Hypothermia On Stroke Volume, Thomas K. Mattingly
The Effect Of Selective Hypothermia On Stroke Volume, Thomas K. Mattingly
Electronic Thesis and Dissertation Repository
Hypothermia is a well-established neuroprotectant. Selective hypothermia to the ischemic area may eliminate side effects while improving induction time. We studied the effect of selective hypothermia on stroke volumes in adult domestic swine. Under general anesthesia, one MCA was occluded transcranially for 3 hours followed by 3 hours of reperfusion. In half the animals, hypothermia was induced during reperfusion via a dual-lumen balloon occlusion catheter placed in the carotid ipsilateral to the ischemic region. Following reperfusion, the animals were sacrificed. Brain MRI and histology were evaluated blinded to the intervention. In a series of animals, the mean temperature achieved was …