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Articles 1 - 30 of 33
Full-Text Articles in Medicine and Health Sciences
Algorithms For Left Atrial Wall Segmentation And Thickness – Evaluation On An Open-Source Ct And Mri Image Database, Rashed Karim, Lauren Emma Blake, Jiro Inoue, Qian Tao, Shuman Jia, R. James Housden, Pranav Bhagirath, Jean Luc Duval, Marta Varela, Jonathan Behar, Loic Cadour, Rob J. Van Der Geest, Hubert Cochet, Maria Drangova, Maxime Sermesant, Reza Razavi, Oleg Aslanidi, Ronak Rajani, Kawal Rhode
Algorithms For Left Atrial Wall Segmentation And Thickness – Evaluation On An Open-Source Ct And Mri Image Database, Rashed Karim, Lauren Emma Blake, Jiro Inoue, Qian Tao, Shuman Jia, R. James Housden, Pranav Bhagirath, Jean Luc Duval, Marta Varela, Jonathan Behar, Loic Cadour, Rob J. Van Der Geest, Hubert Cochet, Maria Drangova, Maxime Sermesant, Reza Razavi, Oleg Aslanidi, Ronak Rajani, Kawal Rhode
Bone and Joint Institute
© 2018 The Authors Structural changes to the wall of the left atrium are known to occur with conditions that predispose to Atrial fibrillation. Imaging studies have demonstrated that these changes may be detected non-invasively. An important indicator of this structural change is the wall's thickness. Present studies have commonly measured the wall thickness at few discrete locations. Dense measurements with computer algorithms may be possible on cardiac scans of Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). The task is challenging as the atrial wall is a thin tissue and the imaging resolution is a limiting factor. It is …
Ciliary Parathyroid Hormone Signaling Activates Transforming Growth Factor-Β To Maintain Intervertebral Disc Homeostasis During Aging, Liwei Zheng, Yong Cao, Shuangfei Ni, Huabin Qi, Zemin Ling, Xin Xu, Xuenong Zou, Tianding Wu, Ruoxian Deng, Bo Hu, Bo Gao, Hao Chen, Yusheng Li, Jianxi Zhu, Francis Tintani, Shadpour Demehri, Amit Jain, Khaled M. Kebaish, Shenghui Liao, Cheryle A. Séguin, Janet L. Crane, Mei Wan, Hongbin Lu, Paul D. Sponseller, Lee H. Riley, Xuedong Zhou, Jianzhong Hu, Xu Cao
Ciliary Parathyroid Hormone Signaling Activates Transforming Growth Factor-Β To Maintain Intervertebral Disc Homeostasis During Aging, Liwei Zheng, Yong Cao, Shuangfei Ni, Huabin Qi, Zemin Ling, Xin Xu, Xuenong Zou, Tianding Wu, Ruoxian Deng, Bo Hu, Bo Gao, Hao Chen, Yusheng Li, Jianxi Zhu, Francis Tintani, Shadpour Demehri, Amit Jain, Khaled M. Kebaish, Shenghui Liao, Cheryle A. Séguin, Janet L. Crane, Mei Wan, Hongbin Lu, Paul D. Sponseller, Lee H. Riley, Xuedong Zhou, Jianzhong Hu, Xu Cao
Bone and Joint Institute
© 2018 The Author(s). Degenerative disc disease (DDD) is associated with intervertebral disc degeneration of spinal instability. Here, we report that the cilia of nucleus pulposus (NP) cells mediate mechanotransduction to maintain anabolic activity in the discs. We found that mechanical stress promotes transport of parathyroid hormone 1 receptor (PTH1R) to the cilia and enhances parathyroid hormone (PTH) signaling in NP cells. PTH induces transcription of integrin αvβ6 to activate the transforming growth factor (TGF)-β-connective tissue growth factor (CCN2)-matrix proteins signaling cascade. Intermittent injection of PTH (iPTH) effectively attenuates disc degeneration of aged mice by direct signaling through NP cells, …
Functional, Motor, And Sensory Assessment Instruments Upon Nerve Repair In Adult Hands: Systematic Review Of Psychometric Properties, Marisa De Cássia Registro Fonseca, Valéria Meireles Carril Elui, Emily Lalone, Natália Claro Da Silva, Rafael Inácio Barbosa, Alexandre Márcio Marcolino, Flávia Pessoni Faleiros Macedo Ricci, Joy C. Macdermid
Functional, Motor, And Sensory Assessment Instruments Upon Nerve Repair In Adult Hands: Systematic Review Of Psychometric Properties, Marisa De Cássia Registro Fonseca, Valéria Meireles Carril Elui, Emily Lalone, Natália Claro Da Silva, Rafael Inácio Barbosa, Alexandre Márcio Marcolino, Flávia Pessoni Faleiros Macedo Ricci, Joy C. Macdermid
Bone and Joint Institute
© 2018 The Author(s). Background: Outcome after nerve repair of the hand needs standardized psychometrically robust measures. We aimed to systematically review the psychometric properties of available functional, motor, and sensory assessment instruments after nerve repair. Methods: This systematic review of health measurement instruments searched databases from 1966 to 2017. Pairs of raters conducted data extraction and quality assessment using a structured tool for clinical measurement studies. Kappa correlation was used to define the agreement prior to consensus for individual items, and intraclass correlation coefficient (ICC) was used to assess reliability between raters. A narrative synthesis described quality and content …
Sodium Nitroglycerin Induces Middle Cerebral Artery Vasodilatation In Young, Healthy Adults, Jenna M. Schulz, Baraa K. Al-Khazraji, J. Kevin Shoemaker
Sodium Nitroglycerin Induces Middle Cerebral Artery Vasodilatation In Young, Healthy Adults, Jenna M. Schulz, Baraa K. Al-Khazraji, J. Kevin Shoemaker
Bone and Joint Institute
© 2018 The Authors Experimental Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society New Findings: What is the central question of this study? Nitric oxide causes dilatation in peripheral vessels; however, whether nitric oxide affects basal cerebral artery dilatation has not been explored. What is the main finding and its importance? This study demonstrated that vasodilatation occurs in the right middle cerebral artery in response to exogenous nitric oxide. However, blood velocity decreased and, therefore, overall cerebral blood flow remained unchanged. This study provides new insight into the role of nitric oxide in cerebral …
Cerebrovascular Compliance Within The Rigid Confines Of The Skull, Mair Zamir, M. Erin Moir, Stephen A. Klassen, Christopher S. Balestrini, J. Kevin Shoemaker
Cerebrovascular Compliance Within The Rigid Confines Of The Skull, Mair Zamir, M. Erin Moir, Stephen A. Klassen, Christopher S. Balestrini, J. Kevin Shoemaker
Bone and Joint Institute
© 2018 Zamir, Moir, Klassen, Balestrini and Shoemaker. Pulsatile blood flow is generally mediated by the compliance of blood vessels whereby they distend locally and momentarily to accommodate the passage of the pressure wave. This freedom of the blood vessels to exercise their compliance may be suppressed within the confines of the rigid skull. The effect of this on the mechanics of pulsatile blood flow within the cerebral circulation is not known, and the situation is compounded by experimental access difficulties. We present an approach which we have developed to overcome these difficulties in a study of the mechanics of …
Dual-Energy Computed Tomography Using A Gantry-Based Preclinical Cone-Beam Microcomputed Tomography Scanner, Justin J. Tse, Joy Dunmore-Buyze, Maria Drangova, David W. Holdsworth
Dual-Energy Computed Tomography Using A Gantry-Based Preclinical Cone-Beam Microcomputed Tomography Scanner, Justin J. Tse, Joy Dunmore-Buyze, Maria Drangova, David W. Holdsworth
Bone and Joint Institute
© The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. Dual-energy microcomputed tomography (DECT) can provide quantitative information about specific materials of interest, facilitating automated segmentation, and visualization of complex three-dimensional tissues. It is possible to implement DECT on currently available preclinical gantry-based cone-beam micro-CT scanners; however, optimal decomposition image quality requires customized spectral shaping (through added filtration), optimized acquisition protocols, and elimination of misregistration artifacts. We present a method for the fabrication of customized …
Health Information On Firefighter Websites: Structured Analysis, Mostin A. Hu, Joy C. Macdermid, Shannon Killip, Margaret Lomotan
Health Information On Firefighter Websites: Structured Analysis, Mostin A. Hu, Joy C. Macdermid, Shannon Killip, Margaret Lomotan
Bone and Joint Institute
© Mostin A Hu, Joy C MacDermid, Shannon Killip, Margaret Lomotan, FIREWELL. Background: Owing to the fact that firefighters have unique health risks, access to firefighter-specific internet-based health information is a potential mechanism for achieving better health and work outcomes. Objective: The objective of our study was to identify the amount and nature of health information resources available on Canadian firefighter-specific websites and the extent to which resources are consistent across websites as a surrogate indicator of diffusion of information. Methods: A search of health resources on firefighter websites (union and employer) for all Canadian provinces, major cities and a …
Appraisal Of Clinical Practice Guideline: American Academy Of Orthopaedic Surgeons Clinical Practice Guideline On The Management Of Osteoarthritis Of The Hip, Ze Lu, Joy C. Macdermid
Appraisal Of Clinical Practice Guideline: American Academy Of Orthopaedic Surgeons Clinical Practice Guideline On The Management Of Osteoarthritis Of The Hip, Ze Lu, Joy C. Macdermid
Bone and Joint Institute
No abstract provided.
Hybrid Polyester Self-Immolative Polymer Nanoparticles For Controlled Drug Release, Michael T. Gambles, Bo Fan, Aneta Borecki, Elizabeth R. Gillies
Hybrid Polyester Self-Immolative Polymer Nanoparticles For Controlled Drug Release, Michael T. Gambles, Bo Fan, Aneta Borecki, Elizabeth R. Gillies
Bone and Joint Institute
© 2018 American Chemical Society. Delivery systems have been developed to address problematic properties of drugs, but the specific release of drugs at their targets is still a challenge. Polymers that depolymerize end-to-end in response to the cleavage of stimuli-responsive end-caps from their termini, commonly referred to as self-immolative polymers, offer high sensitivity to stimuli and have potential for the development of new high-performance delivery systems. In this work, we prepared hybrid particles composed of varying ratios of self-immolative poly(ethyl glyoxylate) (PEtG) and slowly degrading poly(d,l-lactic acid) (PLA). These systems were designed to provide a dual release mechanism consisting of …
Are Large Clinical Trials In Orthopaedic Trauma Justified?, Sheila Sprague, Paul Tornetta, Gerard P. Slobogean, Nathan N. O'Hara, Paula Mckay, Brad Petrisor, Kyle J. Jeray, Emil H. Schemitsch, David Sanders, Mohit Bhandari, Gordon H. Guyatt, Stephen Walter, Jeff Anglen, Michael Bosse, Susan Liew, Parag Sancheti, Kerry Tai, Diane Heels-Ansdell, Lisa Buckingham, Aravin Duraikannan, Stephanie L. Tanner, Rebecca G. Snider, Douglas Altman, Rajiv Gandhi, Markus Bischoff, Gregory J. Della Rocca, Bill Ristevski, Krishan Rajaratnam, Dale Williams, Matthew Denkers, Drew Bednar, John Sadler, Desmond Kwok
Are Large Clinical Trials In Orthopaedic Trauma Justified?, Sheila Sprague, Paul Tornetta, Gerard P. Slobogean, Nathan N. O'Hara, Paula Mckay, Brad Petrisor, Kyle J. Jeray, Emil H. Schemitsch, David Sanders, Mohit Bhandari, Gordon H. Guyatt, Stephen Walter, Jeff Anglen, Michael Bosse, Susan Liew, Parag Sancheti, Kerry Tai, Diane Heels-Ansdell, Lisa Buckingham, Aravin Duraikannan, Stephanie L. Tanner, Rebecca G. Snider, Douglas Altman, Rajiv Gandhi, Markus Bischoff, Gregory J. Della Rocca, Bill Ristevski, Krishan Rajaratnam, Dale Williams, Matthew Denkers, Drew Bednar, John Sadler, Desmond Kwok
Bone and Joint Institute
© 2018 The Author(s). Background: The objective of this analysis is to evaluate the necessity of large clinical trials using FLOW trial data. Methods: The FLOW pilot study and definitive trial were factorial trials evaluating the effect of different irrigation solutions and pressures on re-operation. To explore treatment effects over time, we analyzed data from the pilot and definitive trial in increments of 250 patients until the final sample size of 2447 patients was reached. At each increment we calculated the relative risk (RR) and associated 95% confidence interval (CI) for the treatment effect, and compared the results that would …
Synergic Trial (Synchronizing Exercises, Remedies In Gait And Cognition) A Multi-Centre Randomized Controlled Double Blind Trial To Improve Gait And Cognition In Mild Cognitive Impairment, Manuel Montero-Odasso, Quincy J. Almeida, Amer M. Burhan, Richard Camicioli, Julien Doyon, Sarah Fraser, Karen Li, Teresa Liu-Ambrose, Laura Middleton, Susan Muir-Hunter, William Mcilroy, José A. Morais, Frederico Pieruccini-Faria, Kevin Shoemaker, Mark Speechley, Akshya Vasudev, G. Y. Zou, Nicolas Berryman, Maxime Lussier, Leanne Vanderhaeghe, Louis Bherer
Synergic Trial (Synchronizing Exercises, Remedies In Gait And Cognition) A Multi-Centre Randomized Controlled Double Blind Trial To Improve Gait And Cognition In Mild Cognitive Impairment, Manuel Montero-Odasso, Quincy J. Almeida, Amer M. Burhan, Richard Camicioli, Julien Doyon, Sarah Fraser, Karen Li, Teresa Liu-Ambrose, Laura Middleton, Susan Muir-Hunter, William Mcilroy, José A. Morais, Frederico Pieruccini-Faria, Kevin Shoemaker, Mark Speechley, Akshya Vasudev, G. Y. Zou, Nicolas Berryman, Maxime Lussier, Leanne Vanderhaeghe, Louis Bherer
Bone and Joint Institute
© 2018 The Author(s). Background: Physical exercise, cognitive training, and vitamin D are low cost interventions that have the potential to enhance cognitive function and mobility in older adults, especially in pre-dementia states such as Mild Cognitive Impairment (MCI). Aerobic and progressive resistance exercises have benefits to cognitive performance, though evidence is somewhat inconsistent. We postulate that combined aerobic exercise (AE) and progressive resistance training (RT) (combined exercise) will have a better effect on cognition than a balance and toning control (BAT) intervention in older adults with MCI. We also expect that adding cognitive training and vitamin D supplementation to …
Clinimetrics: Upper Extremity Functional Index, Vanitha Arumugam, Joy C. Macdermid
Clinimetrics: Upper Extremity Functional Index, Vanitha Arumugam, Joy C. Macdermid
Bone and Joint Institute
No abstract provided.
Appraisal Of Clinical Practice Guideline: Management Of Neck Pain, Pavlos Bobos, Joy C. Macdermid
Appraisal Of Clinical Practice Guideline: Management Of Neck Pain, Pavlos Bobos, Joy C. Macdermid
Bone and Joint Institute
No abstract provided.
Beneficial Pleiotropic Antidepressive Effects Of Cardiovascular Disease Risk Factor Interventions In The Metabolic Syndrome, Stephanie J. Frisbee, Sarah S. Singh, Dwayne N. Jackson, Kent A. Lemaster, Samantha A. Milde, J. Kevin Shoemaker, Jefferson C. Frisbee
Beneficial Pleiotropic Antidepressive Effects Of Cardiovascular Disease Risk Factor Interventions In The Metabolic Syndrome, Stephanie J. Frisbee, Sarah S. Singh, Dwayne N. Jackson, Kent A. Lemaster, Samantha A. Milde, J. Kevin Shoemaker, Jefferson C. Frisbee
Bone and Joint Institute
© 2018 The Authors. Background--Although the increased prevalence and severity of clinical depression and elevated cardiovascular disease risk represent 2 vexing public health issues, the growing awareness of their combined presentation compounds the challenge. The obese Zucker rat, a model of the metabolic syndrome, spontaneously develops significant depressive symptoms in parallel with the progression of the metabolic syndrome and, thus, represents a compelling model for study. The primary objective was to assess the impact on both cardiovascular outcomes, specifically vascular structure and function, and depressive symptoms in obese Zucker rats after aggressive treatment for cardiovascular disease risk factors with long-term …
Factors Associated With Health-Related Quality Of Life, Hip Function, And Health Utility After Operative Management Of Femoral Neck Fractures, S. Sprague, M. Bhandari, M. J. Heetveld, S. Liew, T. Scott, S. Bzovsky, D. Heels-Ansdell, Q. Zhou, M. Swiontkowski, E. H. Schemitsch
Factors Associated With Health-Related Quality Of Life, Hip Function, And Health Utility After Operative Management Of Femoral Neck Fractures, S. Sprague, M. Bhandari, M. J. Heetveld, S. Liew, T. Scott, S. Bzovsky, D. Heels-Ansdell, Q. Zhou, M. Swiontkowski, E. H. Schemitsch
Bone and Joint Institute
© 2018 The British Editorial Society of Bone & Joint Surgery. Aims The primary aim of this prognostic study was to identify baseline factors associated with physical health-related quality of life (HRQL) in patients after a femoral neck fracture. The secondary aims were to identify baseline factors associated with mental HRQL, hip function, and health utility. Patients and Methods Patients who were enrolled in the Fixation using Alternative Implants for the Treatment of Hip Fractures (FAITH) trial completed the 12-item Short Form Health Survey (SF-12), Western Ontario and McMaster Universities Arthritis Index, and EuroQol 5-Dimension at regular intervals for 24 …
Position Statement Of The Arthroscopy Association Of Canada (Aac) Concerning Arthroscopy Of The Knee Joint—September 2017, Ivan Wong, Laurie Hiemstra, Olufemi R. Ayeni, Alan Getgood, Cole Beavis, Monika Volesky, Ross Outerbridge, Brendan Sheehan, Robert Mccormack, Robert Litchfield, Daniel Whelan, Nicholas Mohtadi, Catherine Coady, Peter B. Macdonald
Position Statement Of The Arthroscopy Association Of Canada (Aac) Concerning Arthroscopy Of The Knee Joint—September 2017, Ivan Wong, Laurie Hiemstra, Olufemi R. Ayeni, Alan Getgood, Cole Beavis, Monika Volesky, Ross Outerbridge, Brendan Sheehan, Robert Mccormack, Robert Litchfield, Daniel Whelan, Nicholas Mohtadi, Catherine Coady, Peter B. Macdonald
Bone and Joint Institute
No abstract provided.
Patient Perspectives On Improving Osteoarthritis Management In Urban And Rural Communities, Shabana Amanda Ali, Kathleen Ellen Walsh, Marita Kloseck
Patient Perspectives On Improving Osteoarthritis Management In Urban And Rural Communities, Shabana Amanda Ali, Kathleen Ellen Walsh, Marita Kloseck
Bone and Joint Institute
© 2018 Ali et al. Introduction: Although there is no cure for osteoarthritis (OA), there are lifestyle modifications that can mitigate symptoms such as pain, and improve management of the disease. This information is not always translated to community-dwelling seniors. Individuals in rural areas often face additional challenges due to geographic isolation and decreased access to community services. Methods: We used qualitative research methodology (hermeneutic phenomenology) to better understand the lived experiences of urban and rural community-dwelling seniors diagnosed with OA. We explored their sources of information about OA, how they manage their OA pain, and how OA management could …
An Evaluation Of The Structural Validity Of The Shoulder Pain And Disability Index (Spadi) Using The Rasch Model, Christina Jerosch-Herold, Rachel Chester, Lee Shepstone, Joshua I. Vincent, Joy C. Macdermid
An Evaluation Of The Structural Validity Of The Shoulder Pain And Disability Index (Spadi) Using The Rasch Model, Christina Jerosch-Herold, Rachel Chester, Lee Shepstone, Joshua I. Vincent, Joy C. Macdermid
Bone and Joint Institute
© 2017, Springer International Publishing AG, part of Springer Nature. Purpose: The shoulder pain and disability index (SPADI) has been extensively evaluated for its psychometric properties using classical test theory (CTT). The purpose of this study was to evaluate its structural validity using Rasch model analysis. Methods: Responses to the SPADI from 1030 patients referred for physiotherapy with shoulder pain and enrolled in a prospective cohort study were available for Rasch model analysis. Overall fit, individual person and item fit, response format, dependence, unidimensionality, targeting, reliability and differential item functioning (DIF) were examined. Results: The SPADI pain subscale initially demonstrated …
The Contribution Of Health And Psychological Factors In Patients With Chronic Neck Pain And Disability: A Cross-Sectional Study, Pavlos Bobos, Goris Nazari, Stephania Palimeris, Evdokia Billis, Joy C. Macdermid
The Contribution Of Health And Psychological Factors In Patients With Chronic Neck Pain And Disability: A Cross-Sectional Study, Pavlos Bobos, Goris Nazari, Stephania Palimeris, Evdokia Billis, Joy C. Macdermid
Bone and Joint Institute
© 2018, Journal of Clinical and Diagnostic Research. All rights reserved. Introduction: One approach to reduce the burden of neck pain is the management of the prognostic factors that are associated with greater disability. Studies which quantify these predictors can support interventions that attempt to modify these trajectories. Aim: The aim of the present study to determine the contribution of psychological and health factors that are commonly associated with neck pain and disability levels. Materials and Methods: Patients between 18-65 years old were recruited to participate in the present study if they had neck pain for more than three months, …
A Pilot Hole Does Not Reduce The Strains Or Risk Of Fracture To The Lateral Cortex During And Following A Medial Opening Wedge High Tibial Osteotomy In Cadaveric Specimens, K. Bujnowski, A. Getgood, K. Leitch, J. Farr, C. Dunning, T. A. Burkhart
A Pilot Hole Does Not Reduce The Strains Or Risk Of Fracture To The Lateral Cortex During And Following A Medial Opening Wedge High Tibial Osteotomy In Cadaveric Specimens, K. Bujnowski, A. Getgood, K. Leitch, J. Farr, C. Dunning, T. A. Burkhart
Bone and Joint Institute
© 2018 Bujnowski et al. Aim: It has been suggested that the use of a pilot-hole may reduce the risk of fracture to the lateral cortex. Therefore the purpose of this study was to determine the effect of a pilot hole on the strains and occurrence of fractures at the lateral cortex during the opening of a high tibial osteotomy (HTO) and post-surgery loading. Materials and Methods: A total of 14 cadaveric tibias were randomized to either a pilot hole (n = 7) or a no-hole (n = 7) condition. Lateral cortex strains were measured while the osteotomy was opened …
Comparing The Anterior, Posterior And Lateral Approach: Gait Analysis In Total Hip Arthroplasty, Stephen Petis, James Howard, Brent Lanting
Comparing The Anterior, Posterior And Lateral Approach: Gait Analysis In Total Hip Arthroplasty, Stephen Petis, James Howard, Brent Lanting
Bone and Joint Institute
No abstract provided.
Intervention With Citrus Flavonoids Reverses Obesity And Improves Metabolic Syndrome And Atherosclerosis In Obese Ldlr / Mice, Amy C. Burke, Brian G. Sutherland, Dawn E. Telford, Marisa R. Morrow, Cynthia G. Sawyez, Jane Y. Edwards, Maria Drangova, Murray W. Huff
Intervention With Citrus Flavonoids Reverses Obesity And Improves Metabolic Syndrome And Atherosclerosis In Obese Ldlr / Mice, Amy C. Burke, Brian G. Sutherland, Dawn E. Telford, Marisa R. Morrow, Cynthia G. Sawyez, Jane Y. Edwards, Maria Drangova, Murray W. Huff
Bone and Joint Institute
Copyright © 2018 Burke et al. Obesity and its associated metabolic dysfunction and cardiovascular disease risk represent a leading cause of adult morbidity worldwide. Currently available pharmacological therapies for obesity have had limited success in reversing existing obesity and metabolic dysregulation. Previous prevention studies demonstrated that the citrus flavonoids, naringenin and nobiletin, protect against obesity and metabolic dysfunction in Ldlr/ mice fed a high-fat cholesterol-containing (HFHC) diet. However, their effects in an intervention model are unknown. In this report, we show that, in Ldlr/ mice with diet-induced obesity, citrus flavonoid supplementation to a HFHC diet reversed existing obesity and adipocyte …
Psychometric Properties Of The Zephyr Bioharness Device: A Systematic Review, Goris Nazari, Pavlos Bobos, Joy C. Macdermid, Kathryn E. Sinden, Julie Richardson, Ada Tang
Psychometric Properties Of The Zephyr Bioharness Device: A Systematic Review, Goris Nazari, Pavlos Bobos, Joy C. Macdermid, Kathryn E. Sinden, Julie Richardson, Ada Tang
Bone and Joint Institute
© 2018 The Author(s). Background: Technological development and improvements in Wearable Physiological Monitoring devices, have facilitated the wireless and continuous field-based monitoring/capturing of physiologic measures in healthy, clinical or athletic populations. These devices have many applications for prevention and rehabilitation of musculoskeletal disorders, assuming reliable and valid data is collected. The purpose of this study was to appraise the quality and synthesize findings from published studies on psychometric properties of heart rate measurements taken with the Zephyr Bioharness device. Methods: We searched the Embase, Medline, PsycInfo, PuMed and Google Scholar databases to identify articles. Articles were appraised for quality using …
Biomechanical Analysis Using Fea And Experiments Of Metal Plate And Bone Strut Repair Of A Femur Midshaft Segmental Defect, Jason Coquim, Joseph Clemenzi, Mohsen Salahi, Abdurahman Sherif, Pouria Tavakkoli Avval, Suraj Shah, Emil H. Schemitsch, Z. Shaghayegh Bagheri, Habiba Bougherara, Radovan Zdero
Biomechanical Analysis Using Fea And Experiments Of Metal Plate And Bone Strut Repair Of A Femur Midshaft Segmental Defect, Jason Coquim, Joseph Clemenzi, Mohsen Salahi, Abdurahman Sherif, Pouria Tavakkoli Avval, Suraj Shah, Emil H. Schemitsch, Z. Shaghayegh Bagheri, Habiba Bougherara, Radovan Zdero
Bone and Joint Institute
© 2018 Jason Coquim et al. This investigation assessed the biomechanical performance of the metal plate and bone strut technique for fixing recalcitrant nonunions of femur midshaft segmental defects, which has not been systematically done before. A finite element (FE) model was developed and then validated by experiments with the femur in 15 deg of adduction at a subclinical hip force of 1 kN. Then, FE analysis was done with the femur in 15 deg of adduction at a hip force of 3 kN representing about 4 x body weight for a 75 kg person to examine clinically relevant cases, …
Wound Irrigation Does Not Affect Healthrelated Quality Of Life After Open Fractures: Results Of A Randomized Controlled Trial, S. Sprague, B. Petrisor, K. Jeray, P. Mckay, D. Heels-Ansdell, E. Schemitsch, S. Liew, G. Guyatt, S. D. Walter, M. Bhandari
Wound Irrigation Does Not Affect Healthrelated Quality Of Life After Open Fractures: Results Of A Randomized Controlled Trial, S. Sprague, B. Petrisor, K. Jeray, P. Mckay, D. Heels-Ansdell, E. Schemitsch, S. Liew, G. Guyatt, S. D. Walter, M. Bhandari
Bone and Joint Institute
© 2018 Sprague et al. Aims The Fluid Lavage in Open Fracture Wounds (FLOW) trial was a multicentre, blinded, randomized controlled trial that used a 2 3 factorial design to evaluate the effect of irrigation solution (soap versus normal saline) and irrigation pressure (very low versus low versus high) on health-related quality of life (HRQL) in patients with open fractures. In this study, we used this dataset to ascertain whether these factors affect whether HRQL returns to pre-injury levels at 12-months post-injury. Patients and Methods Participants completed the Short Form-12 (SF-12) and the EuroQol-5 Dimensions (EQ-5D) at baseline (pre-injury recall), …
Optimizing Outpatient Total Hip Arthroplasty: Perspectives Of Key Stakeholders, L Churchill, M Pollock, Y Lebedeva, N Pasic
Optimizing Outpatient Total Hip Arthroplasty: Perspectives Of Key Stakeholders, L Churchill, M Pollock, Y Lebedeva, N Pasic
Bone and Joint Institute
Background Advances in surgical techniques combined with multimodal analgesia and early rehabilitation have potentiated early mobilization in patients undergoing total hip arthroplasty (THA). Given an increasing push from patients to accelerate recovery and health care budgetary limitations, there has been growing interest in the implementation of outpatient THA in selected patients. Understanding the patient and primary caregiver experience of outpatient THA is important to optimize care. We aimed to gain insight into patient and caregiver perspectives regarding the perceived advantages and disadvantages of same-day discharge to identify areas of care that can be improved. Method Using a qualitative descriptive approach, …
Validity And Internal Consistency Of The New Knee Society Knee Scoring System, Se Culliton, Dm Bryant, Sj Macdonald, Kathryn Hibbert
Validity And Internal Consistency Of The New Knee Society Knee Scoring System, Se Culliton, Dm Bryant, Sj Macdonald, Kathryn Hibbert
Bone and Joint Institute
BackgroundIn 2012, a new Knee Society Knee Scoring System (KSS) was developed and validated to address the needs for a scoring system that better encompasses the expectations, satisfaction, and physical involvement of a younger, more active population of patients undergoing TKA. Revalidating this tool in a separate population by individuals other than the developers of the scoring system seems important, because such replication would tend to confirm the generalizability of this tool.Questions/purposesThe purposes of this study were (1) to validate the KSS using a separate sample of patients undergoing primary TKA; and (2) to evaluate the internal consistency of the …
Corrigendum To: Erbium-Based Perfusion Contrast Agent For Small-Animal Microvessel Imaging (Contrast Media And Molecular Imaging (2017) 2017 (7368384) Doi: 10.1155/2017/7368384), Justin J. Tse, P. Joy Dunmore-Buyze, Maria Drangova, David W. Holdsworth
Corrigendum To: Erbium-Based Perfusion Contrast Agent For Small-Animal Microvessel Imaging (Contrast Media And Molecular Imaging (2017) 2017 (7368384) Doi: 10.1155/2017/7368384), Justin J. Tse, P. Joy Dunmore-Buyze, Maria Drangova, David W. Holdsworth
Bone and Joint Institute
Copyright © 2018 Justin J. Tse et al. In the article titled "Erbium-Based Perfusion Contrast Agent for Small-Animal Microvessel Imaging" [1], there were errors in the scale bars in Figure 3, which should be corrected as follows: (Figure Presented).
Appraisal Of: Management Of Neck Pain And Associated Disorders: A Clinical Practice Guideline From The Ontario Protocol For Traffic Injury Management (Optima) Collaboration, Saravanan Esakki, Joy C. Macdermid
Appraisal Of: Management Of Neck Pain And Associated Disorders: A Clinical Practice Guideline From The Ontario Protocol For Traffic Injury Management (Optima) Collaboration, Saravanan Esakki, Joy C. Macdermid
Bone and Joint Institute
No abstract provided.
Pain-Quilt: A User-Friendly Tool For The Self-Report And Tracking Of Pain, Chitra Lalloo, Joy Macdermid
Pain-Quilt: A User-Friendly Tool For The Self-Report And Tracking Of Pain, Chitra Lalloo, Joy Macdermid
Bone and Joint Institute
No abstract provided.