Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
The Relation Of The Intestinal Cell Surface To Vitamin B₁₂ Absorption, Robert M. Donaldson Jr.
The Relation Of The Intestinal Cell Surface To Vitamin B₁₂ Absorption, Robert M. Donaldson Jr.
MCV/Q, Medical College of Virginia Quarterly
I have tried to indicate that it is now possible to separate out events occurring at the surface of intestinal absorptive cells. Previous work has shown that intestinal brush borders contain diverse enzymatic activity and that the surface of the intestinal cell is a site for active glucose accumulation. Furthermore, brush border and microvillous membrane preparations now provide direct evidence that intrinsic factor acts at the intestinal cell surface. These studies directly support the concept that a specific receptor for the IF-B₁₂ complex is located on the surface of ileal, but not jejunal absorptive cells. Studies with antibodies against pure …
Amino-Acid Absorption, Bertram Fleshler
Amino-Acid Absorption, Bertram Fleshler
MCV/Q, Medical College of Virginia Quarterly
Most, if not all, ingested protein is transported across the gut as its constituent amino acids. Thus, the way the gut handles amino acids is an important physiologic problem, and their mishandling by the gut in disease states represents an important threat to general body activities. I propose to discuss some of the knowledge that has been gathered over the past 10 to 15 years concerning the mechanisms of amino acid absorption. The data to be presented have been gathered from three major kinds of studies: the studies of in vitro model systems, physiologic studies of humans, and studies of …