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Trajectories In Muscular Strength And Physical Function Among Men With And Without Prostate Cancer In The Health Aging And Body Composition Study, Alexander R. Lucas, Rhonda L. Bitting, Jason Fanning, Scott Isom, W. Jack Rejeski, Heidi D. Klepin, Stephen B. Kritchevsky
Trajectories In Muscular Strength And Physical Function Among Men With And Without Prostate Cancer In The Health Aging And Body Composition Study, Alexander R. Lucas, Rhonda L. Bitting, Jason Fanning, Scott Isom, W. Jack Rejeski, Heidi D. Klepin, Stephen B. Kritchevsky
Health Behavior and Policy Publications
Objectives
To examine and compare changes in strength and physical function from pre- to post-diagnosis among men with prostate cancer (PC, [cases]) and matched non-cancer controls identified from the Health, Aging and Body Composition (Health ABC) study.
Materials and methods
We conducted a longitudinal analysis of 2 strength and 3 physical function-based measures among both cases and controls, identified from a large cohort of community living older adults enrolled in the Health ABC study. We plotted trajectories for each measure and compared cases vs. controls from the point of diagnosis onwards using mixed-effects regression models. For cases only, we examined …