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Full-Text Articles in Medicine and Health Sciences
Molecular Analysis Of Group B Protective Surface Protein, A New Cell Surface Protective Antigen Of Group B Steptococci, Sezgin Erdogan, Peter K. Fagan, Susanne R. Talay, Manfred Rohde, Patricia Ferrieri, Aurea E. Flores, Carlos A. Guzman, Mark J. Walker, Gursharan S. Chhatwal
Molecular Analysis Of Group B Protective Surface Protein, A New Cell Surface Protective Antigen Of Group B Steptococci, Sezgin Erdogan, Peter K. Fagan, Susanne R. Talay, Manfred Rohde, Patricia Ferrieri, Aurea E. Flores, Carlos A. Guzman, Mark J. Walker, Gursharan S. Chhatwal
Faculty of Science, Medicine and Health - Papers: part A
Group B streptococci (GBS) express various surface antigens designated c, R, and X antigens. A new R-like surface protein from Streptococcus agalactiae strain Compton R has been identified by using a polyclonal antiserum raised against the R protein fraction of this strain to screen a lambda Zap library. DNA sequence analysis of positive clones allowed the prediction of the primary structure of a 105-kDa protein designated BPS protein (group B protective surface protein) that exhibited typical features of streptococcal surface proteins such as a signal sequence and a membrane anchor region but did not show significant similarity with other known …