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Does Psychological Status Influence Clinical Outcomes In Patients With Inflammatory Bowel Disease (Ibd) And Other Chronic Gastroenterological Diseases: An Observational Cohort Prospective Study, Antonina A. Mikocka-Walus, Deborah Turnbull, Nicole T. Moulding, Ian G. Wilson, Gerald J. Holtmann, Jane M. Andrews
Does Psychological Status Influence Clinical Outcomes In Patients With Inflammatory Bowel Disease (Ibd) And Other Chronic Gastroenterological Diseases: An Observational Cohort Prospective Study, Antonina A. Mikocka-Walus, Deborah Turnbull, Nicole T. Moulding, Ian G. Wilson, Gerald J. Holtmann, Jane M. Andrews
Graduate School of Medicine - Papers (Archive)
Background: Whether there is a temporal relationship between psychological problems and clinical outcomes in patients with diseases of the digestive tract has not been widely researched. Thus, our aims were 1) To observe and compare prospectively clinical outcomes in relation to psychological co-morbidity in patients with inflammatory bowel disease (IBD), irritable bowel syndrome (IBS) and chronic hepatitis C (HCV) and, 2) To test the hypothesis that patients with psychological co-morbidities are less likely to have a satisfactory response to standard treatment at 12 months. Methods: Overall, 139 patients were enrolled in this observational cohort prospective study. Over the ensuing year, …
"It Doesn't Do Any Harm, But Patients Feel Better": A Qualitative Exploratory Study On Gastroenterologists' Perspectives On The Role Of Antidepressants In Inflammatory Bowel Disease, Antonina A. Mikocka-Walus, Deborah Turnbull, Nicole T. Moulding, Ian G. Wilson, Jane M. Andrews, Gerald J. Holtmann
"It Doesn't Do Any Harm, But Patients Feel Better": A Qualitative Exploratory Study On Gastroenterologists' Perspectives On The Role Of Antidepressants In Inflammatory Bowel Disease, Antonina A. Mikocka-Walus, Deborah Turnbull, Nicole T. Moulding, Ian G. Wilson, Jane M. Andrews, Gerald J. Holtmann
Graduate School of Medicine - Papers (Archive)
Background: Interest in psychological factors in patients with inflammatory bowel disease (IBD) has increased in recent years. It has even been proposed that treating psychological co-morbidities with antidepressants may control disease activity and improve quality of life. Despite this, there is no data on gastroenterologists' attitudes to, and experiences with, antidepressant therapy in patients with IBD. Methods: We conducted semi-structured interviews with 18 gastroenterologists associated with metropolitan teaching hospitals. Qualitative content analysis was used to examine their responses. Results: Seventy-eight percent of gastroenterologists had treated IBD patients with antidepressants for pain, depression and/or anxiety, and insomnia. Antidepressants were reported to …
Antidepressants And Inflammatory Bowel Disease: A Systematic Review, Antonina A. Mikocka-Walus, Deborah Turnbull, Nicole T. Moulding, Ian G. Wilson, Jane M. Andrews, Gerald J. Holtmann
Antidepressants And Inflammatory Bowel Disease: A Systematic Review, Antonina A. Mikocka-Walus, Deborah Turnbull, Nicole T. Moulding, Ian G. Wilson, Jane M. Andrews, Gerald J. Holtmann
Graduate School of Medicine - Papers (Archive)
Background: A number of studies have suggested a link between the patient's psyche and the course of inflammatory bowel disease (IBD). Although pharmacotherapy with antidepressants has not been widely explored, some investigators have proposed that treating psychological comorbidities with antidepressants may help to control disease activity. To date a systematic analysis of the available studies assessing the efficacy of antidepressants for the control of somatic symptoms in IBD patients has not been performed. Methods: We searched electronic databases, without any language restriction. All relevant papers issued after 1990 were examined. Results: 12 relevant publications were identified. All of them referred …