Medicine and Health Sciences Commons^™

Salutogenesis And The Prevention Of Social Death: Cross-Cultural Lessons From Genocide-Impacted Rwandans And Indigenous Youth In Canada, Jobb D. Arnold

Genocide Studies and Prevention: An International Journal

Combining trans-disciplinary theories with cross-cultural ethnographic research, this paper explores community-based approaches to genocide prevention among Canadian-Indigenous groups as well as with Rwandan student genocide survivors. A Salutogenic framework is used to examine community responses to the micro-foundations of genocide (Antonovsky 1987). These processes are explored using first-hand accounts from “New Family” networks of student genocide survivors in Rwanda and members of a Canadian urban-Indigenous “Village.” These perspectives shed light on how locally adaptive, socially networked practices can help promote emergent forms of genocide prevention (Williams 1977). This paper focuses on three areas of local practice that have helped build …

Influences Of Reasoning And Achievement Motivation On Complex Problem Solving In A New Microworld Operationalization, Stephan Bartholdy, Ulrike Kipman

Journal of Global Education and Research

Complex Problem Solving (CPS) can be defined as those psychological processes that enable a person to achieve goals under complex conditions, which are characterized by their complexity, connectivity, dynamics, lack of transparency, and polytely. Although many hypothesized influences have previously been tested concerning their relevance for the process of solving complex problems (e.g., general intelligence), results were often found to be rather heterogeneous. As this was found to be partially caused by fundamental differences between measurements of CPS, a new operationalization was used in the present study: Following the Microworld approach, CPS was assessed in the simulation game Cities: Skylines …

Cancer-Related Risk Behaviors And Screening Intention Among Recreational Sport Athletes, Aldenise P. Ewing

USF Tampa Graduate Theses and Dissertations

The recreational sports arena provides a venue for young adults to increase physical activity and engage in a socially supportive environment. These are both important ways to decrease the risk for chronic diseases. It is assumed that physically active individuals lead healthier lifestyles and are more attuned to their long-term health needs. Recreational sport athletes also engage in risks for adverse cancer outcomes through increased sun exposure, intake of unhealthy diets, and recreational tobacco and alcohol use. It was of interest to assess cancer-related risk factors, cancer knowledge, and theory of planned behavior constructs in this group.

This study involved …

Perceived Discrimination And Cardiovascular Outcomes In Blacks: A Secondary Data Analysis Of The Heart Score Study, Marilyn Aluoch

USF Tampa Graduate Theses and Dissertations

Despite the consistent reduction in morbidity and mortality associated with cardiovascular disease (CVD) over the last four decades, CVD remains the leading cause of death globally. In the United States, Blacks are disproportionately affected by CVD compared to Whites. Blacks are also more likely to report incidence of perceived discrimination. Perceived discrimination has been linked to cardiovascular risk factors such as smoking, hypertension (HTN), hyperlipidemia, and obesity. However, the relationship between perceived discrimination and cardiovascular outcomes such as stroke, myocardial infarction, acute ischemic syndrome, coronary revascularization, and cardiac death remains unclear. The primary goal of this study was to examine …

Introducing A Mobile Health Care Platform In An Underserved Rural Population: Reducing Assimilations Gaps On Adoption And Use Via Nudges, Joseph Hodges

USF Tampa Graduate Theses and Dissertations

Rural communities are often overlooked when it comes to offering cutting edge consumer healthcare technologies. Mobile applications usually exclude populations in rural demographics due to the infrastructure requirements and available technology in the region. The population studied is a low income rural health plan in southwest Georgia. They are uniquely considered as they have the highest healthcare costs in the U.S. and are compared to healthcare costs among higher income populations like Vail, Colorado. Innovations, such as mobile healthcare applications, have the capacity to offset some of these costs, but even if adoption occurs, this does not guarantee use will …

The Role Of Atypical Protein Kinase C In Colorectal Cancer Cells Carcinogenesis, S M Anisul Islam

USF Tampa Graduate Theses and Dissertations

Colorectal cancer (CRC) is the third most common malignancy and the fourth most common cause of cancer-related death worldwide. CRC is a life-threatening disease due to therapy-resistant cancerous cells. The exact mechanisms of cell growth, survival, metastasis and inter & intracellular signaling pathways involved in CRC are still a significant challenge. Moreover, the treatment of metastatic CRC considered palliative for many years aimed for an improved life, with little hope of a cure, highlighting the need for developing novel targeted therapy for CRC. Hence, investigating new molecular mechanism(s) that lead to colorectal carcinogenesis may give insight into the therapeutic target. …

Health-Promoting Behaviors And Subjective Well-Being Among High School Students, Nicholas David W. Smith

USF Tampa Graduate Theses and Dissertations

In positive psychology, a greater emphasis is placed on the presence of indicators of both physical and mental health. This study examined the relationship between 12 health-promoting behaviors and subjective well-being (SWB; e.g., happiness) in a sample of 450 high school aged youth from five high schools in two states. Participants reported on their dietary habits, physical activity, abstinence from tobacco products, abstinence from alcohol, and sleep hygiene (i.e., 8 unique components) as well as a multidimensional assessment of SWB (i.e., life satisfaction, positive affect, and negative affect). It was hypothesized that increased engagement in each of the health-promoting behaviors …

Least Of My Worries: Food Security, Diet Quality, And Antiretroviral Adherence Among People Living With Hiv, Charlotte Ann Noble

USF Tampa Graduate Theses and Dissertations

More than forty years into the epidemic, HIV continues to impact the health and well-being of millions of people – nearly 37 million across the globe and in excess of 1 million in the U.S. – more than 44% of which live in the Southern United States. HIV continues to disproportionally affect marginalized populations, and vast amounts of money, time, and effort have been spent to understand how to slow the rate of new infections and improve health outcomes for People Living with HIV (PLWH). This study aims to understand the experience of living with and managing HIV while on …

A Comparison Of Different Modeling Techniques To Establish Token Reinforcers In Classroom Settings, Spencer B. Gauert

USF Tampa Graduate Theses and Dissertations

Prior research has supported the use of reinforcer-based methods in school settings. Video based modeling methods for establishing conditioned reinforcers without the need for explicit pairing with primary reinforcers can help to extend the use of these resources into new contexts. The use of video based conditioning has potential applications in school settings to increase academic skills without the use of more costly-to-implement reinforcer systems. However, conditioning of this kind might be restricted by the need to individually condition stimuli with different participants. The current study evaluated effects of video based conditioning on relative rate of sight word reading across …

Exploration Of Gratitude In Cardiovascular Health: Mediators, Medication Adherence And Psychometrics, Lakeshia A. Cousin

USF Tampa Graduate Theses and Dissertations

The purpose of this dissertation was to explore the effect of gratitude on cardiovascular health outcomes using mediators, medication adherence, and psychometrics. The specific aims were to (1) establish the state of the science for gratitude and cardiovascular health outcomes via a state-of-the-science literature review, (2) explore mediators affecting gratitude and medication adherence using a structural equation model in patients with cardiovascular disease, and (3) analyze the psychometric properties of the Gratitude Questionnaire-6, a self-report questionnaire designed to assess individual differences to express dispositional gratitude, to provide evidence for the validity and reliability of the instrument in African Americans at …

“Man Plans But Ultimately, God Decides”: A Phenomenological Investigation Of The Contextual Family Planning Beliefs Of Recently Resettled Congolese Refugee Women In West Central Florida., Linda Bomboka Wilson

USF Tampa Graduate Theses and Dissertations

Existent demographic changes in the United States are largely a result of the current international refugee crisis. Within the past three years, there has been an influx of refugees who were affected by the wars in the Democratic Republic of Congo (DRC). Congolese refugees were the highest number of all refugee groups to arrive in the United States in Fiscal Years 2016-2018, yet little is known about their lived experiences, particularly as they apply to reproductive health and family planning in general. Congolese refugee women who resettle in the United States are unique because many lived in refugee camps for …

“We Can Learn Some Things From Them, But They Can Learn Some Things From Us Too”: Intergenerational Perceptions Of Shared Infant Feeding Information, Alexis L. Woods Barr

USF Tampa Graduate Theses and Dissertations

Breastfeeding is associated with unparalleled benefits for infants, mothers, families and society. In light of the breastfeeding disparities and health disparities experienced by the African American community, their women and children stand to gain the most from breastfeeding practices compared to other first-food feeding methods. Moreover, African American mothers are constantly exposed to messages, images, and stereotypes about motherhood (from multiple channels of communication) which influences their infant feeding practices. Many of these exposures send mixed messages and tend to be cultural contradictions of Black motherhood. What complicates this issue is the shortage of research that investigates the intergenerational infant …

Understanding The Family Planning Care Experiences Of Young Black Women Using An Intersectionality Mixed Methods Approach, Rachel G. Logan

USF Tampa Graduate Theses and Dissertations

Introduction: Black women in the U.S. disproportionately experience unintended pregnancy, particularly as compared to their white counterparts. When racial and ethnic disparities in reproductive health are combined with other marginalized identities, such as low social status and young age, Black women’s risk of negative health outcomes may increase and further produce disadvantage.

Objective: The overall objective of this research was to understand the family planning care experiences of young Black women.

Methods: This study used a transformative mixed methods design to understand young Black women’s most recent family planning care experience in the last 12 months through Intersectionality, Psychological Reactance, …

An Assessment Of The Role Of Florida Pharmacists In The Administration Of Inactivated Influenza Vaccine To Pregnant Women, Oluyemisi O. Falope

USF Tampa Graduate Theses and Dissertations

The influenza vaccine is a safe and effective vaccine in preventing influenza infection in the general population. The Centers for Disease Control (CDC) recommend that pregnant women receive influenza inactivated vaccine (IIV) due to the high morbidity and mortality associated with influenza infection in pregnant women. Despite the recommendation, the U.S. national influenza vaccine uptake rates among pregnant women continue to remain low. Studies have shown barriers to influenza vaccine uptake in pregnant women to include issues with access, unavailability of vaccine, and lack of time during prenatal visits. These barriers can be overcome using pharmacists because, among healthcare providers, …

Epidemiological Analysis Of Malaria Decrease In El Salvador From 1955 Until 2017, Tatiana I. Gardellini Guevara

USF Tampa Graduate Theses and Dissertations

The disease of malaria is complex, with clinical presentation that ranges from severe and complicated to mild and uncomplicated or even to asymptomatic malaria. A recent effort made by several world organizations has shown important advances in the effort to control and eradicate malaria. Following the general ordinance established by the trans-border organizations, each country has tried to define, according to their local geopolitical scenario, individual ¨road maps¨ to succeed in reducing the morbidity and mortality caused by malaria. Moreover, it is now accepted universally that these road maps need to be revised and appropriated in order to correct actions …

Multimodal Treatment And Neoadjuvant Chemotherapy Trends, Utilization And Survival Effects In Intrahepatic Cholangiocarcinoma – A Propensity Score Analysis, Ovie Utuama

USF Tampa Graduate Theses and Dissertations

Intrahepatic Cholangiocarcinomas (ICC) are fatal malignancies common among the elderly. Patients are diagnosed late and often relapse, even after curative-intent surgery (CIS). In this context, additional systemic chemotherapy (multimodal treatment) is recommended for most patients but reported survival benefits are minimal and are limited to small single institutional studies. For this reason, using a national cancer registry, we sought to characterize multimodal treatment trends and utilization in general and neoadjuvant chemotherapy, specifically, as well as evaluate their survival effects among the larger population. We hypothesized that, 1). Elderly ICC patients would have survival benefits equivalent to younger patients, 2). Neoadjuvant …

Understanding The Influence Of The Cancer Microenvironment On Metabolism And Metastasis, Shonagh Russell

USF Tampa Graduate Theses and Dissertations

Cancer is a complex and heterogeneous disease. Not only is there considerable variability between different cancer types, but there is enormous variability between and within patients who have the same type of cancer. Within tumors, there are multiple cell types, including cancer cells, stromal cells, and immune cells. The tumor microenvironment often induces the healthy cells to become pro-tumorigenic. Cell metabolism is exquisitely sensitive to changes in the tumor microenvironment and can be measured to infer the aggressiveness of cancer and predict response to therapy. In this dissertation, we aim to understand how the microenvironment, specifically low pH, affects the …

Interventions To Improve Older Driver Safety, Bernadette A. Fausto

USF Tampa Graduate Theses and Dissertations

Increased longevity coupled with age-related declines that compromise driving safety and fragility render older adults as vulnerable road users (Oxley & Whelan, 2008). To address this public health concern, researchers continue to investigate interventions to improve older driver safety. The current dissertation consists of two papers examining: a) the state of the literature on older driver interventions and b) the efficacy of one approach, Useful Field of View cognitive training, to reduce at-fault crash involvement. The first paper sought to identify and quantify the effects of different interventions among older adults on outcomes of crashes, on-road driving performance, self-reported outcomes …

Evaluating The Effect Of Temperature On A Human Parasite And Its Intermediate Snail Host: Implications For A Changing Climate, Karena H. Nguyen

USF Tampa Graduate Theses and Dissertations

Global climate change is impacting the emergence, re-emergence, prevalence, and incidence of infectious diseases worldwide, including parasitic diseases of humans (Blum and Hotez 2018). Neglected tropical diseases, defined as a group of parasitic diseases affecting developing countries in the tropics (Hotez et al. 2007), are of particular concern because these diseases occur in areas that are also expected to experience rapid population growth and agricultural development in the coming decades. As human population and food demand increase, the greater the likelihood of humans encountering intermediate hosts that either inhabit agricultural areas or are impacted by agricultural development, which will influence …

Isokinetic Sampling Efficiency Differences For Blunt Edge Vs Sharp Edge Sampling Probes, Cory A. Treloar

USF Tampa Graduate Theses and Dissertations

This project aims to determine if sampling efficiency differences are present between a sharp edge probe and a blunt edge probe during isokinetic sampling. To answer this question, isokinetic sampling was performed inside a wind tunnel. Sampling was performed with the sharp edge probe and compared to data previously obtained using the blunt edge probe. Two different particle sizes were used, 0.50 m and 2.00 m, at air velocities of 0.5 m/s, 1.0 m/s and 2.0 m/s in the wind tunnel. Results showed that there is a difference in sampling efficiency between the two probes and a larger difference in …

Sundaas Story: A Mixed-Methods Study Of Household Sanitation Provisioning In Urban Informal Housing In India, Sarita Vijay Panchang

USF Tampa Graduate Theses and Dissertations

The aims of this research were to examine sanitation insecurity in urban informal housing through the lens of the built environment, social disparities, and health implications. While the Millennium Development Goals for halving the global proportion of people without access to safe drinking water were met ahead of schedule, progress fell short for sanitation, creating new objectives for the Sustainable Development Goals to be met in 2030. Much research in the Global South is dedicated to community-level sanitation promotion, but often presumes a rural rather than urban setting. Urban informal housing settings constitute a unique challenge due to the range …

Associations Between Mental Health, Academic Success, And Perceived Stress Among High School Freshman In Accelerated Coursework, Andrew S. Jenkins

USF Tampa Graduate Theses and Dissertations

Youth in accelerated curricula programs are an understudied population in relation to groups who struggle academically. To date, few studies have been conducted examining relationships between psychopathology symptomology, life satisfaction, academic achievement, and perceived stress. To address this, the current study completed a secondary analysis of an archival dataset in order to expand upon previous research into the predictive relationships between mental health (psychopathology and life satisfaction; beginning of year) and students’ subsequent academic achievement and perceived stress (assessed mid-year). Furthermore, the current study investigated the predictive effects of mid-year academic achievement (course grades) and perceived stress on students’ subsequent …

Autonomy, Suffering, And The Practice Of Medicine: A Relational Approach, Michael A. Stanfield

USF Tampa Graduate Theses and Dissertations

In this project, I argue that the conventional view of personal autonomy that is operational in contemporary American culture, bioethics and medical practice places undue emphasis on individualism and a limited range of personal qualities and attributes (such as self-sufficiency). Instead, I argue in favor of a relational approach to autonomy which recognizes that each person that exists has certain minimal connections or relations to others, and these connections/relations are identity-forming. Unfortunately, current medical practices have tended to overemphasize individuality and choice (consistent with the conventional view) while minimizing or excluding these relational aspects. As a result, informed consent and …

The Relationship Between Continuous Glucose Monitor (Cgm) Derived Metrics And Indices Of Glycemic Control, Ryan Bailey

USF Tampa Graduate Theses and Dissertations

Introduction: Both hypoglycemia (low blood glucose) and hyperglycemia (high blood glucose) are common among individuals with type 1 diabetes and are associated with severe medical complications, therefore it is essential that health care providers are able to accurately measure glycemic control. Measures derived from continuous glucose monitoring (CGM) may provide more accurate measurements of glycemia than the commonly used HbA1c blood test.

Methods: Data from the Juvenile Diabetes Research Foundation (JDRF) clinical trial to assess the efficacy of continuous glucose monitoring was used to estimate the ability of CGM composite scores to predict time in range, time in hyperglycemia and …

Hybrid Fusion Protein For Inhibition Of Multiple Proteases For Chronic Wound Healing, Graham L. Strauss

USF Tampa Graduate Theses and Dissertations

Many diseases display a multitude of relevant factors that contribute to the persistence of the disease and difficulty treating it. The multifactorial characteristics of some diseases lead to the requirement of combination of treatments in order to restore health. The latter may necessitate the mixing of treatments, medications, and therapeutics to first halt the disease, then assist the human body in returning itself to a state of normality. For example, chronic wounds exhibit this multifactor characteristic in which there exist many factors that lead to the body’s inability to properly heal in a timely manner. This presents a further threat …

The Impact Of Calculators On A Test Of Clinician Numeracy: A Randomized Controlled Trial, Anne A. Taylor, Douglas R. Corfield, Lucie M. Byrne-Davis

Numeracy

Clinician numeracy (CN), the ability to use and understand quantitative data in patient care, is an important skill for healthcare professionals. Nonetheless, it is recognized that many healthcare professionals, including doctors, have deficiencies in CN, and that this may affect patient safety. In our previous research using the Medical Interpretation and Numeracy Test (MINT), we found that many doctors in training in the UK had low CN. However, participants were not permitted to use calculators when taking the MINT, even though staff has access to calculators in clinical practice. Therefore, our original study may have underestimated doctors’ CN, compared to …

Mitigating Barriers To Chronic Disease Risk Factor Prevention And Management In Disadvantaged Communities, Krys M. Johnson

USF Tampa Graduate Theses and Dissertations

Background: The incidence and prevalence of chronic disease (CD) has increased in recent decades due to the advent of CD management and life-extending technologies. To address this burden on the population and healthcare system, evidence-based CD prevention programs have been developed to reduce the incidence and therefore the prevalence of these diseases. Despite the development and dissemination of effective interventions, African-Americans and Hispanics have disproportionately higher prevalence of CD and associated risk factors and disproportionately lower participation in CD prevention programs. Overweight/obesity and CDs may have intergenerational effects, with overweight adults being more likely to have overweight children who are …

Mapping Reward Values To Cues, Locations, And Objects: The Influence Of Reward Associations On Visual Attention, Constanza De Dios

USF Tampa Graduate Theses and Dissertations

Previous work has attempted to fit reward-driven attentional selection as being exogenous (stimulus-driven) or endogenous (goal-driven). However, recent work suggests that reward’s effects on attention depend on the type of stimulus feature that the motivational information is imparted during learning (incentive salience). If true, then reward should not be limited to solely impacting early perceptual or late categorization processes attention. The current study used event-related potentials (ERPs) to test the idea that reward’s effects on attention depend on the process that the reward information is embedded – early perceptual or late categorization. Results demonstrated reward-driven effects on perceptual representation when …

Targeting Pten For Therapy In Cancer And Ptenopathies, Emily Palumbo

USF Tampa Graduate Theses and Dissertations

PTEN, a dual protein and lipid phosphatase, regulates a myriad of cellular functions including PI3K pathway signaling, cell migration, proliferation, invasion and apoptosis. PTEN mutations often lead to multiple malignancies, including prostate, breast, endometrial, skin and brain cancers, associated with hyperactive PI3K signaling. PTEN mutations have also been associated with a variety of other diseases, classified as PTEN Hamartoma Tumor Syndromes (PHTS). In addition, compromised function or reduced expression of PTEN due to non-genomic mechanisms are associated with many types of hyperproliferative diseases, such as restenosis and neoplastic diseases, including melanoma, lung, breast, prostate and colon cancers. Although PI3K pathway …

An Eye Opener In Stroke: Mitochondrial Dysfunction And Stem Cell Repair In Stroke-Induced Retinal Ischemia, Hung Vu Thien Nguyen

USF Tampa Graduate Theses and Dissertations

Stoke is a leading cause of disability and mortality across the globe, making it a global health crisis. However, treatments for stroke remain limited with narrow therapeutic time window. Visual impairment negatively affects patients’ quality of life. During stroke, the disruption in blood flow might affect both brain and eye resulting in cerebral and retinal ischemia. Currently, there is a lack of treatment option that targets both cerebral and retinal ischemia. Ischemic stroke pathology is complex and multiphasic. The ischemic event is followed by a secondary cascade of inflammatory cytokines exacerbating the initial focal injury and expanding into the penumbra. …