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Articles 1 - 8 of 8
Full-Text Articles in Medicine and Health Sciences
Moving Forward With Ketamine Therapy: Ensuring Safety, Efficacy, And Accessibility In Depression Treatment, Julienne Desanto
Moving Forward With Ketamine Therapy: Ensuring Safety, Efficacy, And Accessibility In Depression Treatment, Julienne Desanto
Undergraduate Honors Theses
Ketamine, a medication long used in anesthesia, has emerged as a promising treatment for depression and other mental health disorders. Its rapid onset of action and mechanism, which differs from traditional antidepressants by targeting NMDA receptors, offers a novel approach to managing depressive symptoms. Despite its potential, ketamine's use outside anesthesia, particularly in off-label ketamine clinics, is fraught with regulatory, safety, and accessibility challenges. This paper explores the historical medical use of ketamine and its emerging role in mental health treatment. It compares the efficacies and administration routes of different forms of ketamine, including intravenous (IV) and intranasal (nasal spray) …
Algorithmic Bias: Causes And Effects On Marginalized Communities, Katrina M. Baha
Algorithmic Bias: Causes And Effects On Marginalized Communities, Katrina M. Baha
Undergraduate Honors Theses
Individuals from marginalized backgrounds face different healthcare outcomes due to algorithmic bias in the technological healthcare industry. Algorithmic biases, which are the biases that arise from the set of steps used to solve or analyze a problem, are evident when people from marginalized communities use healthcare technology. For example, many pulse oximeters, which are the medical devices used to measure oxygen saturation in the blood, are not able to accurately read people who have darker skin tones. Thus, people with darker skin tones are not able to receive proper health care due to their pulse oximetry data being inaccurate. This …
Making The Case For Psychedelics: Comparing Alternative Treatment Options For Depression, Nicole Amavisca
Making The Case For Psychedelics: Comparing Alternative Treatment Options For Depression, Nicole Amavisca
Undergraduate Honors Theses
Given the number of people who are treated for depression each year and the knowledge that treatments work differently for everyone, there is a pressing need to provide a variety of treatment options. Although psychedelic research had been halted for a few decades due to recreational abuse, there has been revived interest due to its therapeutic potential in the treatment of mood disorders and addiction. As an example, the hallucinogen ketamine has recently been approved as a treatment for depression, which has opened the door for broadening the discussion on psychedelic research. Although the research is limited, psilocybin mimics ketamine …
Examining Perceptions Of Anorexia Nervosa, Polly Mcgonigle
Examining Perceptions Of Anorexia Nervosa, Polly Mcgonigle
Undergraduate Honors Theses
Anorexia nervosa (AN) is an eating disorder characterized by a restriction of energy intake, an intense fear of gaining weight, and often distorted body image. AN has the second highest mortality rate of all psychiatric disorders, due to high suicide rates and medical complications associated with malnutrition. An estimated 10% of those who have AN die because of the disorder (Insel, 2012). Interacting factors—genetic, biological, environmental, and psychosocial—contribute to the etiology and maintenance of AN. However, outside of research settings, AN is misunderstood as having primarily environmental roots (Salafia, et. al). Blame is placed on societal expectations and the disorder …
The Life-Saving Drug That No One Knows About: Naloxone Education And The Health Belief Model, Sarah Tilford
The Life-Saving Drug That No One Knows About: Naloxone Education And The Health Belief Model, Sarah Tilford
Undergraduate Honors Theses
Naloxone hydrochloride, popularly known by the brand name Narcan, is an emergency treatment used to reverse an overdose on opioid drugs. The CDC reports upwards of 26,000 individuals saved by naloxone between 1996 and 2014 (Centers for Disease Control and Prevention, 2015). Despite this success rate, those outside of the medical field largely remain unaware of what naloxone is or how they can use it in an emergency, leading to needless loss of life. Many studies focusing on naloxone access and education have been unable to offer findings meant to increase the use and ownership of the drug by lay …
The Role Of Dopamine In Decision Making Processes In Drosophila Melanogaster, Michelle C. Bowers
The Role Of Dopamine In Decision Making Processes In Drosophila Melanogaster, Michelle C. Bowers
Undergraduate Honors Theses
Understanding the neural processes that mediate decision making is a relatively new field of investigation in the scientific community. With the ultimate goal of understanding how humans decide between one path and another, simpler models such as Drosophila Melanogaster, the common fruit fly, are often utilized as a way of determining the neural circuits involved in these decision-making processes. One of the most important decisions flies make is the decision of where to lay their eggs (oviposit). Choosing the proper substrate upon which to lay eggs is a crucial decision that can ultimately impact their fecundity. This paper investigates the …
Gaze-Driven Video Games As Vision Training: A Case Study In Cerebral Palsy, Mckenna Wade
Gaze-Driven Video Games As Vision Training: A Case Study In Cerebral Palsy, Mckenna Wade
Undergraduate Honors Theses
Cerebral Palsy is a disorder that primarily affects motor control, but frequently impacts gaze behavior as well. Due to the primary therapeutic emphasis on motor symptoms, there is a dearth of therapies available for gaze behavior in Cerebral Palsy. Based on research suggesting that video games and Augmented Reality have been useful for improvement of gaze behavior and rehabilitation for other impaired individuals, this case study applies a set of therapeutic gaze-dependent Augmented Reality video games to an adolescent male with Spastic Diplegic Cerebral Palsy. The video games were determined to be a good fit for the participant by the …
Light Dependent Endolysosomal Defects In A Photoreceptor Model Of Alzheimer's Disease, Michelle S. Smith
Light Dependent Endolysosomal Defects In A Photoreceptor Model Of Alzheimer's Disease, Michelle S. Smith
Undergraduate Honors Theses
Alzheimer’s disease (AD) is a neurodegenerative disease which is the 6th leading cause of death in the US. AD pathology is thought to be linked to the accumulation and aggregation of toxic proteins, amyloid-beta and tau. AD development and neurodegeneration is proposed to be caused by the toxic effects of these protein accumulations, specifically amyloid-beta, as postulated by the amyloid-cascade hypothesis. To study the relationship between amyloid-beta and overall neuronal health, a study was carried out using an amyloid-expressing fruit fly photoreceptor model. Using this model, toxicity of amyloid in a stressed lysosomal system induced by light, an established …