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Full-Text Articles in Medicine and Health Sciences

Improving The Palatability Of Colonoscopy Preparations, Phuong Anh Hoang Nguyen, Darnell Leon Cuylear, Heather Elizabeth Canavan Nov 2018

Improving The Palatability Of Colonoscopy Preparations, Phuong Anh Hoang Nguyen, Darnell Leon Cuylear, Heather Elizabeth Canavan

Shared Knowledge Conference

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. The most reliable screening method of CRC is a colonoscopy which requires a 4-Liter polymer with electrolytes preparation. Two in five patients are non-compliant to their colonoscopy schedules, with many patients who abstain reporting refusal due to significant discomfort associated with this preparation. Furthermore, there are distinct gender differences in the tolerance of colonoscopy preparations in male and female populations. We hypothesize the differences in clinic are a result of toxic effects of the drug associated with poor mixing by individual patients. PEG, the drug, …


An Engineer’S Take On The Bone-Ligament Interface: Utilizing Novel Technology To Improve Clinical Outcomes, Emma Garcia Nov 2018

An Engineer’S Take On The Bone-Ligament Interface: Utilizing Novel Technology To Improve Clinical Outcomes, Emma Garcia

Shared Knowledge Conference

Ligament repair is a common surgical practice with a significant lack of viable replacements. The current gold standard for repair is the use of tendon grafts from cadavers or from another place in the patient’s body; however, these often cause more problems than they solve including immune responses or a lack of mobility in another place in the body. Synthetic replacements are of growing interest, though the ability to mimic the complex structure of the ligament and how it connects to the bone remains an obstacle. Our lab built a 3D bioprinter combined with an electrospinner to address this complicated …


Computational Investigation Of The Interactions Between Bioactive Compounds And Biological Assemblies, Tye D. Martin Nov 2018

Computational Investigation Of The Interactions Between Bioactive Compounds And Biological Assemblies, Tye D. Martin

Shared Knowledge Conference

Design of small molecules is an ongoing focus for developing agents against pathogenic viruses and bacteria that are threats to worldwide health. Viruses such as Zika feature assemblies of repeat peptide subunits or capsid proteins which are potential targets for antiviral compounds. Other protein assemblies are implicated in pathology of Alzheimer’s Disease (AD) and additional neurodegenerative diseases characterized by large assemblies of misfolded proteins such as amyloid-beta (Aβ) and tau. Recent studies on a class of conjugated polyelectrolytes (CPEs) with phenylene ethynylene moieties and charged functional groups have shown potential both as bioactive antimicrobials and theragnostic sensing agents for tracking …


Targeted Exercise Therapy To Enhance Neural Activation, Terence Moriarty, Kelsey Bourbeau, Bryanne Bellovary, Micah Zuhl Nov 2018

Targeted Exercise Therapy To Enhance Neural Activation, Terence Moriarty, Kelsey Bourbeau, Bryanne Bellovary, Micah Zuhl

Shared Knowledge Conference

Various types of exercise therapies, have been implemented into treatment for those suffering from psychological disorders and traumatic brain injury. The prefrontal cortex (PFC), which houses key cognitive constructs is responsive to exercise, and is commonly measured using functional near infrared spectroscopy (fNIRS). Evidence suggests that exercise mediates neural adaptation through increased blood flow and neurogenesis, which enhances neural activation leading to improved cognitive performance. However, the intensity of exercise that has the most robust impact on brain blood flow is currently unknown. Purpose. Therefore, the primary aim of the study is to compare PFC activation during cognitive tasks performed …


Gender Differences In First Authors, Peer Reviewers, And Grand Rounds Presenters In Medicine, Parisa Mortaji Nov 2018

Gender Differences In First Authors, Peer Reviewers, And Grand Rounds Presenters In Medicine, Parisa Mortaji

Shared Knowledge Conference

Women are underrepresented in senior academic positions that depend on accomplishments like presentations and publications, and gender bias has shown to be a factor. We studied whether gender differences existed in multiple internal medicine venues: first authorship in a national trainee poster competition; first authorship in a national specialty-specific poster competition; peer reviewer-ship in three prestigious medical journals; and in presentations at UNM grand rounds. We found some progress in gender parity overall, but not yet enough. We first studied gender differences in authorship among residents in a 2015 national internal medicine resident poster competition; we found more authors were …


Effectiveness Of Therapy Interventions For Heterotopic Ossification About The Elbow: A Systematic Review, Cole Burns Nov 2018

Effectiveness Of Therapy Interventions For Heterotopic Ossification About The Elbow: A Systematic Review, Cole Burns

Shared Knowledge Conference

Heterotopic ossification (HO) is the presence of bone where bone normally does not exist. HO forms frequently at the elbow from various conditions including: Fracture, orthopedic surgery, certain genetic disorders, neurological injuries, amputation, and brain injury. A diagnosis of HO at the elbow can lead to decreases in range of motion which effects the person’s functional independence. Surgical excision to remove the bone can be done to improve functional outcomes, but is typically not performed until a year has passed from the time of injury. Even then, there have been instances where people have experienced recurrent HO post-surgery. Because of …


Improving The Palatability Of Colonoscopy Preparations, Phuong Anh Hoang Nguyen, Sarah Mounho, Darnell Cuylear, Heather Canavan Nov 2018

Improving The Palatability Of Colonoscopy Preparations, Phuong Anh Hoang Nguyen, Sarah Mounho, Darnell Cuylear, Heather Canavan

Shared Knowledge Conference

Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. The most reliable screening method of CRC is a colonoscopy which requires a 4-Liter polymer with electrolytes preparation. Two in five patients are non-compliant to their colonoscopy schedules, with many patients who abstain reporting refusal due to significant discomfort associated with this preparation. Furthermore, there are distinct gender differences in the tolerance of colonoscopy preparations in male and female populations. We hypothesize the differences in clinic are a result of toxic effects of the drug associated with poor mixing by individual patients. PEG, the drug, …


Trying To Cover The Sun With Your Thumb: A Critical Ethnography Of Maternity Care Provision In Rural Northern New Mexico, Abigail Reese Nov 2018

Trying To Cover The Sun With Your Thumb: A Critical Ethnography Of Maternity Care Provision In Rural Northern New Mexico, Abigail Reese

Shared Knowledge Conference

Access to maternity care is disappearing for women across rural America. In New Mexico, women often travel long distances in order to access hospitals and providers that offer childbirth services, as these resources are primarily concentrated in metropolitan areas. Although data on provider distribution is available, very few studies have explored the maternity care access crisis from the perspectives of the midwives and physicians who work in rural areas. The purpose of this study was to explore barriers and facilitators to the provision of childbirth services from providers’ perspectives with the intent of informing policy debates around the maintenance of …


3d Bioprinting And Near-Field Electrospinning Composite Scaffolds For The Bone-Ligament Interface, Emma Garcia, Christina Salas, Matthew N. Rush, Christopher Buksa, Marissa Perez, Ava Mauser, Steven Nery, Fermin Prieto, Darielys Morales Nov 2018

3d Bioprinting And Near-Field Electrospinning Composite Scaffolds For The Bone-Ligament Interface, Emma Garcia, Christina Salas, Matthew N. Rush, Christopher Buksa, Marissa Perez, Ava Mauser, Steven Nery, Fermin Prieto, Darielys Morales

Shared Knowledge Conference

3D bioprinting is an additive manufacturing technique that can utilize a range of bioactive materials to construct specific architectures that mimic native tissue. Near-field electrospinning (NFE) offers precise alignment control to create non-woven mats with high tensile strengths. We built a custom E-spin printer that enables layer-by-layer alternating deposition between 3D bioprinting and NFE to create composite scaffolds for the bone-ligament interface. This complex region is difficult to simulate due to its functionally graded mechanical and biochemical properties. We created NFE poly(caprolactone) highly aligned micro-fibers which formed collagen fibril-like bundles. Poly(ethylene glycol) diacrylate with decellularized bone was encased in the …


Early Interventions Providers’ Knowledge Of Evidence-Based Practices For Working With Children With Autism, Mariah Groll Nov 2018

Early Interventions Providers’ Knowledge Of Evidence-Based Practices For Working With Children With Autism, Mariah Groll

Shared Knowledge Conference

Autism spectrum disorder (ASD) is developmental disability that is associated with social communication deficits and repetitive or restrictive behaviors. Research has systematically identified evidence-based strategies for working with individuals with ASD. It has demonstrated the importance of early intervention. There is, however, limited research on early intervention providers’ (e.g., speech-language pathologists (SLPs) and developmental specialists (DS)) knowledge of evidence-based strategies for working with individuals with ASD. To further explore this issue, we conducted an online survey that examined the ASD knowledge of early intervention DSs and SLPs in the state of NM. The survey included a demographics section, a section …


The Association Between Negative Socioeconomic Determinants Of Health And Poor Nutritional Status In Children Of Low Income Families Living In New Mexico, Molly A. Morrison Nov 2018

The Association Between Negative Socioeconomic Determinants Of Health And Poor Nutritional Status In Children Of Low Income Families Living In New Mexico, Molly A. Morrison

Shared Knowledge Conference

When evaluating the prevalence of obesity rates throughout New Mexico (NM), it appears these rates have reached a plateau. A recent study conducted by the NM Department of Health (DOH) found that NM was among 19 other states that have had a first time decrease in child obesity rates among low income families. However, when examined deeper, when looking at geographical areas throughout NM, hidden geography of weight disparities become apparent. Although obesity rates may have decreased in some areas, they have increased in others. The purpose of this study is to effectively evaluate variability in weight trends between geographical …


Cost-Effectiveness Analysis Of Enzalutamide, Abiraterone Acetate Plus Prednisone, Cabazitaxel Plus Prednisone For The Treatment Of Visceral Metastatic Castration Resistant Prostate Cancer (Mcrpc) After Docetaxel Therapy, Yazan K. Barqawi Nov 2018

Cost-Effectiveness Analysis Of Enzalutamide, Abiraterone Acetate Plus Prednisone, Cabazitaxel Plus Prednisone For The Treatment Of Visceral Metastatic Castration Resistant Prostate Cancer (Mcrpc) After Docetaxel Therapy, Yazan K. Barqawi

Shared Knowledge Conference

Background: Prostate cancer is the second leading cause of death after lung cancer among men in the US. The America Cancer Society predicts 164,690 new cases and 29,430 prostate cancer deaths in 2018. In 2014, nearly US $13.4 billion was spent on prostate cancer in the US and expected to reach US $15.4 billion by 2020. Objective: To conduct a cost-effective analysis of visceral mCRPC therapies post-docetaxel failure from a US healthcare payer perspective utilizing life-time horizon Markov model. These medications received highest National Comprehensive Cancer Network guideline recommendation to treat visceral mCRPC post-docetaxel failure. Methods: A pharmacoeconomic model was …


The Critical Need For Mental Health Education To Be Mandated In New Mexico's Public Schools, Bonnie L. Murphy Nov 2018

The Critical Need For Mental Health Education To Be Mandated In New Mexico's Public Schools, Bonnie L. Murphy

Shared Knowledge Conference

Based on a review of research and best practices in mental health awareness and skills, this inquiry project argues for state legislative policies that would require mental health awareness and skills in the K-12 curriculum. Mental health affects individual accomplishments in every stage of people’s lives beginning in early childhood and throughout the life cycle. Prevention and treatment of mental illness plays a key role in the ability of an individual to cope with loss and develop resiliency and perseverance in challenging times and to make better decisions that improve the individual’s life and the lives of those around them. …