Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Publication
- Publication Type
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Traumatic Brain Injury Increases Levels Of Mir-21 In Extracellular Vesicles: Implications For Neuroinflammation, Emily B. Harrison, Colleen G. Hochfelder, Benjamin G. Lamberty, Brittney M. Meays, Brenda M. Morsey, Matthew L. Kelso, Howard S. Fox, Sowmya V. Yelamanchili
Traumatic Brain Injury Increases Levels Of Mir-21 In Extracellular Vesicles: Implications For Neuroinflammation, Emily B. Harrison, Colleen G. Hochfelder, Benjamin G. Lamberty, Brittney M. Meays, Brenda M. Morsey, Matthew L. Kelso, Howard S. Fox, Sowmya V. Yelamanchili
Journal Articles: Pharmacology & Experimental Neuroscience
No abstract provided.
Expression And Function Of Inflammation-Associated Micrornas In Traumatic Brain Injury, Emily Harrison
Expression And Function Of Inflammation-Associated Micrornas In Traumatic Brain Injury, Emily Harrison
Theses & Dissertations
MicroRNAs (miRNAs) are important regulators of gene expression. Many neurological diseases, including traumatic brain injury alter expression of miRNAs in the brain. However, the function of these molecules in the context of TBI is largely unknown. Here we report multiple potential roles for miRNAs in TBI, some of which extend beyond the traditional model of post-transcriptional regulation, highlighting that these RNA molecules may have broader implications for the neurobiology of disease. We found that miR-155 plays an essential role in interferon expression after CCI and that miR-155 contributes to TBI induced anxiety, potentially through regulation of interferons. Expression of miR-155 …