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Chlorothalonil Exposure And Cancer Incidence Among Pesticideapplicator Participants In The Agricultural Health Study, Alicia M. Mozzachio, Jennifer A. Rusiecki, Jane A. Hoppin, Rajeev Mahajan, Rahulkumar Patel, Laura Beane-Freeman, Michael Cr Alavanja
Chlorothalonil Exposure And Cancer Incidence Among Pesticideapplicator Participants In The Agricultural Health Study, Alicia M. Mozzachio, Jennifer A. Rusiecki, Jane A. Hoppin, Rajeev Mahajan, Rahulkumar Patel, Laura Beane-Freeman, Michael Cr Alavanja
Uniformed Services University of the Health Sciences
Background: Chlorothalonil is a broad spectrum, non-systemic fungicide widely used to control diseases affecting over 50 fruit, vegetable, and agricultural crops. Despite its extensive use for over 30 years, little is known about the potential human carcinogenicity associated with the routine application of chlorothalonil. Rodent studies have shown evidence of renal tubular carcinomas and adenomas. We explored cancer incidence with chlorothalonil exposure using data from the Agricultural Health Study, a prospective cohort of licensed pesticide applicators in Iowa and North Carolina.
Methods: Licensed private and commercial pesticide applicators were recruited into this study from 1993 to 1997. Detailed information regarding …