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University of Kentucky

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

2021

Carbapenem-resistance; carbapenemase; Enterobacteriaceae; healthcare-acquired infection; intensive care unit; sink drain

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Risk Factors Of Carbapenem-Resistant Enterobacteriaceae Acquisition Among Adult Intensive Care Unit Patients At A Kentucky Academic Medical Center, Jason Eric Wilson, Jason Wilson Jan 2021

Risk Factors Of Carbapenem-Resistant Enterobacteriaceae Acquisition Among Adult Intensive Care Unit Patients At A Kentucky Academic Medical Center, Jason Eric Wilson, Jason Wilson

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Background: This study aimed to identify risk factors of carbapenem-resistant Enterobacteriaceae (CRE) acquisition among adult intensive care unit (ICU) patients at a Kentucky academic medical center and to evaluate sink drains as a possible environmental reservoir of carbapenem-resistant organism (CRO) transmission.

Methods: A retrospective cohort study was conducted from October 1, 2013 through October 31, 2016. Intensive care unit patients were screened for CRE at admission and weekly until discharge. Cases were defined as patients who tested positive for CRE on ICU admission day 3 or greater. Sink drains were sampled for CROs in selected units from January 2018 through …