Medicine and Health Sciences Commons^™

Celiac Disease Prevalence And The Characteristics Of Celiac Patients In The United Arab Emirates, Two Centers Study, Asma Hamed Alnababteh

Dissertations

Celiac Disease (CD) is a chronic autoimmune gastrointestinal disorder caused by genetic susceptibility to gluten and affects around 1% of the population worldwide. CD can occur at any age and is diagnosed by detecting specific serological biomarkers and histopathological changes in the duodenal biopsy. In the United Arab Emirates, there is a lack of studies describing CD in children or adults; this thesis aimed at researching the epidemiology of celiac disease in among the populations in the United Arab Emirates.

Two Studies were conducted to achieve the research objectives, study one was conducted in Cleveland Clinic Abu Dhabi (CCAD) and …

Experimental Investigation On The Relationship Between Lead Exposure And Thyroids In Diabetes, Salah Sumar Ali Al-Zadjali

Dissertations

Lead exposure can cause multiple systemic toxicities, particularly affecting the hematopoietic, nervous and renal systems. However, its effects on the thyroid functions are not well elucidated and the published studies are controversial. In addition, although there are several experimental thyroid models, each one of them has its own limitations. Accordingly, in this dissertation, we investigated the possible relationship between lead exposure, thyroid functions and short-term systemic toxicity in two animal models, namely normal (non-diabetic) and diabetic animals. We also investigated the possibility of developing a hormonal thyroid model. In the non-diabetic model, Wistar rats were divided into five groups and …

Experimental Investigation On The Relationship Between Lead Exposure And Thyroids In Diabetes., Salah Sumar Ali Al-Zadjali

Dissertations

Lead exposure can cause multiple systemic toxicities, particularly affecting the hematopoietic, nervous and renal systems. However, its effects on the thyroid functions are not well elucidated and the published studies are controversial. In addition, although there are several experimental thyroid models, each one of them has its own limitations. According, in this dissertation, we investigated the possible relationship between lead exposure, thyroid functions and short-term systemic toxicity in two animal models, namely normal (non-diabetic) and diabetic animals. We also investigated the possibility of developing a hormonal thyroid model.

In the non-diabetic model, Wistar rats were divided into five groups and …