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Full-Text Articles in Medicine and Health Sciences
Potential Association Of Blood Transfusion In Deceased Donors With Outcomes Of Liver Transplantation In The United States, Kenji Okumura, Abhay Dhand, Ryosuke Misawa, Hiroshi Sogawa, Gregory Veillette, Seigo Nishida
Potential Association Of Blood Transfusion In Deceased Donors With Outcomes Of Liver Transplantation In The United States, Kenji Okumura, Abhay Dhand, Ryosuke Misawa, Hiroshi Sogawa, Gregory Veillette, Seigo Nishida
NYMC Faculty Publications
BACKGROUND: Donor blood transfusion may potentially affect transplant outcomes through an inflammatory response, recipient sensitization, or transmission of infection. The aim of this study was to evaluate the association of donor blood transfusion with outcomes of liver transplantation (LT). METHODS: From January 2004 to December 2022, donor blood transfusion information was available for 113,017 adult recipients of LT in the United Network for Organ Sharing database and was classified into 4 levels of transfusion: no-transfusion (N = 68,130), transfusion of 1-5 units (N = 33,629), 6-10 units (N = 8067), and >10 units (N = 5329). Recipient survival analysis was …
Peripheral Nerve Stimulation For Treating Acute Pain Following Traumatic Fracture: A Case Report Of Rapid-Onset Analgesia Without Motor Blockade, Ammar Siddiqui, Nitin Sekhri, Irim Salik, Fang Yu, Jeff L. Xu
Peripheral Nerve Stimulation For Treating Acute Pain Following Traumatic Fracture: A Case Report Of Rapid-Onset Analgesia Without Motor Blockade, Ammar Siddiqui, Nitin Sekhri, Irim Salik, Fang Yu, Jeff L. Xu
NYMC Faculty Publications
Analgesia following acute traumatic fracture remains a clinical challenge. Pain relief via peripheral nerve stimulation (PNS) is a promising treatment modality due to its opioid-sparing effects and rapid, reversible sensory blockade without motor blockade. We present the case of a patient who suffered a traumatic tibial plateau fracture. A popliteal sciatic PNS device was placed on postoperative day 1 following inadequate pain control. The patient reported marked pain relief, a significant reduction in morphine milligram equivalent (MME) utilization, and improved early functional recovery. The PNS lead was removed at the patient's 2-month follow-up visit without any adverse events.
Braf Inhibitors In Braf-Mutated Colorectal Cancer: A Systematic Review, Wajeeha Aiman, Muhammad Ashar Ali, Samer Jumean, Ummul Asfeen, Jose Garcia, Murad Quirem, Amaar Ahmad, Mohammad Nabil Rayad, Osama Alkhlaifat, Bader Al Omour, Venkata S. Chemarthi, Michael Maroules, Gunwant Guron, Hamid Shaaban
Braf Inhibitors In Braf-Mutated Colorectal Cancer: A Systematic Review, Wajeeha Aiman, Muhammad Ashar Ali, Samer Jumean, Ummul Asfeen, Jose Garcia, Murad Quirem, Amaar Ahmad, Mohammad Nabil Rayad, Osama Alkhlaifat, Bader Al Omour, Venkata S. Chemarthi, Michael Maroules, Gunwant Guron, Hamid Shaaban
NYMC Faculty Publications
Colorectal cancer (CRC) is the second-leading cause of cancer-related deaths globally. BRAF mutation is present in about 10% of CRC patients and is associated with a poor response to chemotherapy. These patients have a relatively poor prognosis. This review aims to assess the efficacy and safety of BRAF inhibitors in BRAF-mutated CRC patients. A literature search was performed on PubMed and Embase, and clinical trials relevant to BRAF inhibitors in CRC were included. Data were extracted for efficacy and safety variables. Two randomized clinical trials (n = 765) and eight non-randomized trials (n = 281) were included based on inclusion …
Frequency, Characteristics, And Correlates Of Cognitive Complaints In A Cohort Of Individuals With Post-Acute Sequelae Of Covid-19, Cayla Muschel, Sean T. Lynch, Rhea Dornbush, Lidia Klepacz, Sivan Shahar, Stephen J. Ferrando
Frequency, Characteristics, And Correlates Of Cognitive Complaints In A Cohort Of Individuals With Post-Acute Sequelae Of Covid-19, Cayla Muschel, Sean T. Lynch, Rhea Dornbush, Lidia Klepacz, Sivan Shahar, Stephen J. Ferrando
NYMC Faculty Publications
BACKGROUND: Cognitive complaints are among the most frequent symptoms of post-acute sequelae of COVID-19 (PASC). This study aimed to investigate the frequency, characteristics, and clinical correlates of cognitive complaints (CC) in PASC, particularly in relation to objective neuropsychological (NP) performance. METHODS: Seventy-four participants underwent psychiatric, medical, and NP testing approximately 7 months after acute COVID-19. The Patient Assessment of Own Functioning Inventory (PAOFI) was used to characterize the frequency and severity of CC in domains of memory, language, and cognitive/executive function. The associations of CC with sociodemographic, medical, psychiatric, and NP variables were assessed utilizing correlational analysis, logistic regression, and …
Early Postnatal Expression Of Tgfβ-1 And Fgf-2 Correlates With Regenerative Functions Of Unrestricted Somatic Stem Cell Infusion After Rabbit Gmh-Ivh, Dina A. Finkel, Ana Malfa, Yanling Liao, Deepti Purohit, Furong Hu, Davud Sulaymankhil, Sai Abhishek Narra, Karen Hussein, Selvakumar Subbian, Mitchell S. Cairo, Govindaiah Vinukonda, Edmund F. La Gamma
Early Postnatal Expression Of Tgfβ-1 And Fgf-2 Correlates With Regenerative Functions Of Unrestricted Somatic Stem Cell Infusion After Rabbit Gmh-Ivh, Dina A. Finkel, Ana Malfa, Yanling Liao, Deepti Purohit, Furong Hu, Davud Sulaymankhil, Sai Abhishek Narra, Karen Hussein, Selvakumar Subbian, Mitchell S. Cairo, Govindaiah Vinukonda, Edmund F. La Gamma
NYMC Faculty Publications
Intraventricular hemorrhage (IVH) is a severe complication of preterm birth associated with white matter injury (WMI) and reduced neurogenesis. IVH commonly arises from the germinal matrix, a highly cellular, transient structure, where all precursor cells are born, proliferate, and migrate during brain development. IVH leads to reduced progenitor cell proliferation and maturation and contributes to WMI. Interruption of oligodendrocyte lineage (OL) proliferation and maturation after IVH will prevent myelination. We evaluated whether unrestricted somatic stem cells (USSCs) could recover OL lineage, as USSC release multiple relevant growth factors and cytokines. The effects of USSC infusion at 24 hours after IVH …
Rare Median And Musculocutaneous Nerve Fusion With Intraoperative Electrical Confirmation: Illustrative Case, Audrey Huang, Sima Vazquez, Jose Dominguez, Avinash Mohan, Jin Li, Jared M. Pisapia
Rare Median And Musculocutaneous Nerve Fusion With Intraoperative Electrical Confirmation: Illustrative Case, Audrey Huang, Sima Vazquez, Jose Dominguez, Avinash Mohan, Jin Li, Jared M. Pisapia
NYMC Faculty Publications
BACKGROUND: Nerve transfer is a surgical technique in which a redundant or expendable fascicle is transferred or coapted to an injured nerve distal to the site of injury for the purpose of reinnervation. Successful nerve transfer is dependent on correct intraoperative identification of donor and recipient nerves. OBSERVATIONS: An 8-year-old male was recommended for ulnar nerve fascicle to biceps branch of musculocutaneous nerve transfer to restore elbow flexion weakness after a demyelinating spinal cord injury. The biceps branch was identified approximately midway along the upper arm. Proximal musculocutaneous nerve stimulation induced hand movement and electromyography activity in the median nerve …
Higher Dose Alglucosidase Alfa Is Associated With Improved Overall Survival In Infantile-Onset Pompe Disease (Iopd): Data From The Pompe Registry, Priya S. Kishnani, David Kronn, Shugo Suwazono, Alexander Broomfield, Juan Llerena, Zuhair Nasser Al-Hassnan, Julie L. Batista, Kathryn M. Wilson, Magali Periquet, Nadia Daba, Andreas Hahn, Yin-Hsiu Chien
Higher Dose Alglucosidase Alfa Is Associated With Improved Overall Survival In Infantile-Onset Pompe Disease (Iopd): Data From The Pompe Registry, Priya S. Kishnani, David Kronn, Shugo Suwazono, Alexander Broomfield, Juan Llerena, Zuhair Nasser Al-Hassnan, Julie L. Batista, Kathryn M. Wilson, Magali Periquet, Nadia Daba, Andreas Hahn, Yin-Hsiu Chien
NYMC Faculty Publications
BACKGROUND: Studies indicate that doses of alglucosidase alfa (ALGLU) higher than label dose (20 mg/kg every other week) improve clinical outcomes in infantile-onset Pompe disease (IOPD). We investigated data from the Pompe Registry to determine the association between ALGLU dose and survival in IOPD. RESULTS: We included 332 IOPD patients from the Registry as of January 2022 who had cardiomyopathy and were first treated at age < 1 year. We used Cox proportional hazards models to estimate hazard ratios (HR) and 95% confidence intervals (CI) for the association between ALGLU as a time-varying exposure and survival, adjusting for age at first treatment, sex, and cross-reactive immunologic material (CRIM)/immune tolerance induction (ITI) status. Dose was measured as average relative dose received over time (in multiples of label dose, range > 0 to 4 times label dose), current dose, and lagged dose. 81% patients received label dose at treatment initiation. Over time, 52% received a higher dose. Higher ALGLU dose over time was associated with …
Training Postural Balance Control With Pelvic Force Field At The Boundary Of Stability, Isirame Omofuma, Victor Santamaria, Xupeng Ai, Sunil Agrawal
Training Postural Balance Control With Pelvic Force Field At The Boundary Of Stability, Isirame Omofuma, Victor Santamaria, Xupeng Ai, Sunil Agrawal
NYMC Faculty Publications
This study characterizes the effects of a postural training program on balance and muscle control strategies in a virtual reality (VR) environment. The Robotic Upright Stand Trainer (RobUST), which applies perturbative forces on the trunk and assistive forces on the pelvis, was used to deliver perturbation-based balance training (PBT) in a sample of 10 healthy participants. The VR task consisted of catching, aiming, and throwing a ball at a target. All participants received trunk perturbations during the VR task with forces tailored to the participant's maximum tolerance. A subgroup of these participants additionally received assistive forces at the pelvis during …
Reduction Of Th2 Inflammation And Fibrosis In Eosinophilic Esophagitis In A Murine Model By Citri Reticulatae Pericarpium, Mingzhuo Cao, Zeqian Wang, Yuan Wang, Heyun Jing, Yijia Meng, Yu Geng, Xiu-Min Li, Mingsan Miao
Reduction Of Th2 Inflammation And Fibrosis In Eosinophilic Esophagitis In A Murine Model By Citri Reticulatae Pericarpium, Mingzhuo Cao, Zeqian Wang, Yuan Wang, Heyun Jing, Yijia Meng, Yu Geng, Xiu-Min Li, Mingsan Miao
NYMC Faculty Publications
ETHNOPHARMACOLOGICAL RELEVANCE: Inflammation and subepithelial fibrosis play major roles in the early pathology of eosinophilic esophagitis (EoE). However, there are currently no pharmacotherapeutic interventions that directly target eosinophilic esophagitis. Citri Reticulatae Pericarpium (CRP, known as Chen-Pi) is one of most frequently used qi-regulating drugs in Chinese medicine and nutrition. CRP is rich with flavonones and polymethoxy flavones, both of which exhibit superior anti-inflammatory, anti-allergic and anti-fibrosis effects. This study is to investigate intervention effect of CRP on EoE, to identify its active compounds and to explore its underlying mechanisms. METHODS: The CRP extract was obtained by liquid-liquid extraction with 70% …
Groin Wound Management After Decannulation Of Veno-Arterial Extracorporeal Membrane Oxygenation In Heart Transplantation: Role Of Sartorius Muscle Flap, Ameesh Isath, Vasiliki Gregory, Suguru Ohira, Avi Levine, Abhay Dhand, Igor Laskowski, Romeo Mateo, Sateesh Babu, David Spielvogel, Masashi Kai
Groin Wound Management After Decannulation Of Veno-Arterial Extracorporeal Membrane Oxygenation In Heart Transplantation: Role Of Sartorius Muscle Flap, Ameesh Isath, Vasiliki Gregory, Suguru Ohira, Avi Levine, Abhay Dhand, Igor Laskowski, Romeo Mateo, Sateesh Babu, David Spielvogel, Masashi Kai
NYMC Faculty Publications
BACKGROUND: The management of complex groin wounds following VA-ECMO after heart transplant (HT) is uncertain due to limited experience. Sartorius muscle flaps (SMF) have been used in vascular surgery for groin wound complications. However, their use in HT recipients with perioperative VA-ECMO is unclear. This study aims to describe characteristics and outcomes of HT patients with groin complications after arterial decannulation for femoral VA-ECMO. METHODS: We retrospectively reviewed HT patients who underwent peri-transplant femoral VA-ECMO at our institution from April 2011 to February 2023. Patients were categorized into two groups based on the presence of cannulation-related wound complications. RESULTS: Among …
Assessment Of Cerebral Autoregulatory Function And Inter-Hemispheric Blood Flow In Older Adults With Internal Carotid Artery Stenosis Using Transcranial Doppler Sonography-Based Measurement Of Transient Hyperemic Response After Carotid Artery Compression, Rita Magyar-Stang, Hanga Pál, Borbála Csányi, Anna Gaál, Zsuzsanna Mihály, Zsófia Czinege, Tamas Csipo, Zoltan Ungvari, Péter Sótonyi, Andrea Varga, Tamás Horváth, Dániel Bereczki, Akos Koller, Róbert Debreczeni
Assessment Of Cerebral Autoregulatory Function And Inter-Hemispheric Blood Flow In Older Adults With Internal Carotid Artery Stenosis Using Transcranial Doppler Sonography-Based Measurement Of Transient Hyperemic Response After Carotid Artery Compression, Rita Magyar-Stang, Hanga Pál, Borbála Csányi, Anna Gaál, Zsuzsanna Mihály, Zsófia Czinege, Tamas Csipo, Zoltan Ungvari, Péter Sótonyi, Andrea Varga, Tamás Horváth, Dániel Bereczki, Akos Koller, Róbert Debreczeni
NYMC Faculty Publications
Unhealthy vascular aging promotes atherogenesis, which may lead to significant internal carotid artery stenosis (CAS) in 5 to 7.5% of older adults. The pathogenic factors that promote accelerated vascular aging and CAS also affect the downstream portion of the cerebral microcirculation in these patients. Primary treatments of significant CAS are eversion endarterectomy or endarterectomy with patch plasty. Factors that determine adequate hemodynamic compensation and thereby the clinical consequences of CAS as well as medical and surgical complications of carotid reconstruction surgery likely involve the anatomy of the circle of Willis (CoW), the magnitude of compensatory inter-hemispheric blood flow, and the …
Global And Endothelial G-Protein Coupled Receptor 75 (Gpr75) Knockout Relaxes Pulmonary Artery And Mitigates Hypoxia-Induced Pulmonary Hypertension, Catherine A. D'Addario, Shun Matsumura, Atsushi Kitagawa, Gregg M. Lainer, Frank Zhang, Melinee D'Silva, Mohammad Y. Khan, Ghezal Froogh, Artiom Gruzdev, Darryl C. Zeldin, Michal L. Schwartzman, Sachin A. Gupte
Global And Endothelial G-Protein Coupled Receptor 75 (Gpr75) Knockout Relaxes Pulmonary Artery And Mitigates Hypoxia-Induced Pulmonary Hypertension, Catherine A. D'Addario, Shun Matsumura, Atsushi Kitagawa, Gregg M. Lainer, Frank Zhang, Melinee D'Silva, Mohammad Y. Khan, Ghezal Froogh, Artiom Gruzdev, Darryl C. Zeldin, Michal L. Schwartzman, Sachin A. Gupte
NYMC Faculty Publications
RATIONALE: Pulmonary hypertension (PH) is a multifactorial disease with a poor prognosis and inadequate treatment options. We found two-fold higher expression of the orphan G-Protein Coupled Receptor 75 (GPR75) in leukocytes and pulmonary arterial smooth muscle cells from idiopathic PH patients and from lungs of C57BL/6 mice exposed to hypoxia. We therefore postulated that GPR75 signaling is critical to the pathogenesis of PH. METHODS: To test this hypothesis, we exposed global (Gpr75) and endothelial cell (EC) GPR75 knockout (EC-Gpr75) mice and wild-type (control) mice to hypoxia (10% oxygen) or normal atmospheric oxygen for 5 weeks. We then recorded echocardiograms and …
Assessment Of Comorbid Symptoms In Pediatric Autonomic Dysfunction, Sally E. Tarbell, Erin L. Olufs, Philip R. Fischer, Gisela Chelimsky, Mohammed T. Numan, Marvin Medow, Hasan Abdallah, Shelley Ahrens, Jeffrey R. Boris, Ian J. Butler, Thomas C. Chelimsky, Craig Coleby, John E. Fortunato, Raewyn Gavin, Janice Gilden, Renato Gonik, Kelsey Klaas, Lauren Marsillio, Erin Marriott, Laura A. Pace, Paul Pianosi, Pippa Simpson, Julian Stewart, Natalie Van Waning, Debra E. Weese-Mayer
Assessment Of Comorbid Symptoms In Pediatric Autonomic Dysfunction, Sally E. Tarbell, Erin L. Olufs, Philip R. Fischer, Gisela Chelimsky, Mohammed T. Numan, Marvin Medow, Hasan Abdallah, Shelley Ahrens, Jeffrey R. Boris, Ian J. Butler, Thomas C. Chelimsky, Craig Coleby, John E. Fortunato, Raewyn Gavin, Janice Gilden, Renato Gonik, Kelsey Klaas, Lauren Marsillio, Erin Marriott, Laura A. Pace, Paul Pianosi, Pippa Simpson, Julian Stewart, Natalie Van Waning, Debra E. Weese-Mayer
NYMC Faculty Publications
PURPOSE: Pediatric patients with autonomic dysfunction and orthostatic intolerance (OI) often present with co-existing symptoms and signs that might or might not directly relate to the autonomic nervous system. Our objective was to identify validated screening instruments to characterize these comorbidities and their impact on youth functioning. METHODS: The Pediatric Assembly of the American Autonomic Society reviewed the current state of practice for identifying symptom comorbidities in youth with OI. The assembly includes physicians, physician-scientists, scientists, advanced practice providers, psychologists, and a statistician with expertise in pediatric disorders of OI. A total of 26 representatives from the various specialties engaged …
Devaluing Babies: Neonatal Implications Of Proposed Changes In Pediatric Residency Training, Shetal Shah, Nicolle Fernández Dyess, Patrick J. Myers
Devaluing Babies: Neonatal Implications Of Proposed Changes In Pediatric Residency Training, Shetal Shah, Nicolle Fernández Dyess, Patrick J. Myers
NYMC Faculty Publications
No abstract provided.
Restrictive Points Of Entry Into Abortion Care In Ireland: A Qualitative Study Of Expectations And Experiences With The Service, Dyuti Chakravarty, Joanna Mishtal, Lorraine Grimes, Karli Reeves, Bianca Stifani, Deirdre Duffy, Mark Murphy, Mary Favier, Patricia Horgan, Wendy Chavkin, Antonella Lavelanet
Restrictive Points Of Entry Into Abortion Care In Ireland: A Qualitative Study Of Expectations And Experiences With The Service, Dyuti Chakravarty, Joanna Mishtal, Lorraine Grimes, Karli Reeves, Bianca Stifani, Deirdre Duffy, Mark Murphy, Mary Favier, Patricia Horgan, Wendy Chavkin, Antonella Lavelanet
NYMC Faculty Publications
This article focuses on access to early medical abortion care under Section 12 of the Health (Regulation of Termination of Pregnancy) Act 2018, in Ireland and identifies existing barriers resulting from gaps in current policy design. The article draws primarily on qualitative interviews with 24 service users, 20 primary healthcare providers in the community and 27 key informants, including from grassroots groups that work with women from different migrant communities, to examine service users' experiences accessing early medical abortions on request up to 12 weeks gestation. The interviews were part of a wider mixed-methods study from 2020-2021 examining the barriers …
Saliva As A Diagnostic Tool To Measure Polycyclic Aromatic Hydrocarbon Exposure In Dental Patients Exposed To Intimate Partner Violence (Ipv), Aramandla Ramesh, Leslie R. Halpern, Janet H. Southerland, Samuel E. Adunyah, Pandu R. Gangula
Saliva As A Diagnostic Tool To Measure Polycyclic Aromatic Hydrocarbon Exposure In Dental Patients Exposed To Intimate Partner Violence (Ipv), Aramandla Ramesh, Leslie R. Halpern, Janet H. Southerland, Samuel E. Adunyah, Pandu R. Gangula
NYMC Faculty Publications
BACKGROUND: Social habits such as tobacco use, alcohol consumption, and chemically contaminated diet contribute to poor oral health. Intimate Partner Violence (IPV) is a global public health epidemic which can exacerbate the prevalence of health conditions affecting a victim's lifespan. This study investigates using saliva as a biomarker for detecting levels of benzo(a)pyrene [B(a)P]; a toxicant present in cigarette smoke and barbecued meat in a population of IPV + female patients. METHODS: A cross-sectional IRB-approved study utilized 63 female participants (37 African Americans [AA], and 26 non-African Americans [NAA]), who provided consent for the study. Participants submitted samples of saliva, …
Editor-In-Chief Foreword: Can We Engage In Evidence-Based Medicine By Using Practice-Based Evidence?, Leslie Citrome
Editor-In-Chief Foreword: Can We Engage In Evidence-Based Medicine By Using Practice-Based Evidence?, Leslie Citrome
NYMC Faculty Publications
No abstract provided.
Exploring Hematoma Expansion Shift With Recombinant Factor Viia: A Pooled Analysis Of 4 Randomized Controlled Trials, Vignan Yogendrakumar, Stephan A. Mayer, Thorsten Steiner, Joseph P. Broderick, Dar Dowlatshahi
Exploring Hematoma Expansion Shift With Recombinant Factor Viia: A Pooled Analysis Of 4 Randomized Controlled Trials, Vignan Yogendrakumar, Stephan A. Mayer, Thorsten Steiner, Joseph P. Broderick, Dar Dowlatshahi
NYMC Faculty Publications
BACKGROUND: Hematoma expansion shift (HES) analysis can be used to assess the biological effect of a hemostatic therapy for intracerebral hemorrhage. In this study, we applied HES analysis to individual patient data from 4 randomized controlled trials evaluating rFVIIa (recombinant factor VIIa) 80 μg/kg to placebo. METHODS: We generated polychotomous strata of HES using absolute growth thresholds (≤0/<6/≥6 mL) and quintiles of percent volume change. The relationship between treatment and HES was assessed using proportional odds models. Differences in subgroups based on baseline volume (≥ or <20 mL), and time from symptom onset to treatment (≤ or >2 hours) were explored with testing for interactions. RESULTS: The primary analysis included 721 patients. At 24 hours, 36% (134/369) of rFVIIa-treated patients exhibited no hematoma expansion as compared with 25% of placebo (88/352)-treated patients. Significant expansion (≥6 mL) was reduced by …
Rare Tumors: Opportunities And Challenges From The Children's Oncology Group Perspective, Kris Ann Schultz, Murali Chintagumpala, Jin Piao, Kenneth S. Chen, Rachana Shah, Robyn D. Gartrell, Emily Christison-Lagay, Farzana Pashnakar, Jesse L. Berry, Allison F. O'Neill, Lauren M. Vasta, Ashley Flynn, Sarah G. Mitchell, Brittani Kn Seynnaeve, Jeremy Rosenblum, Samara L. Potter, Junne Kamihara, Carlos Rodriguez-Galindo, Douglas S. Hawkins, Theodore W. Laetsch
Rare Tumors: Opportunities And Challenges From The Children's Oncology Group Perspective, Kris Ann Schultz, Murali Chintagumpala, Jin Piao, Kenneth S. Chen, Rachana Shah, Robyn D. Gartrell, Emily Christison-Lagay, Farzana Pashnakar, Jesse L. Berry, Allison F. O'Neill, Lauren M. Vasta, Ashley Flynn, Sarah G. Mitchell, Brittani Kn Seynnaeve, Jeremy Rosenblum, Samara L. Potter, Junne Kamihara, Carlos Rodriguez-Galindo, Douglas S. Hawkins, Theodore W. Laetsch
NYMC Faculty Publications
While all childhood cancers are rare, tumors that are particularly infrequent or underrepresented within pediatrics are studied under the umbrella of the Children's Oncology Group Rare Tumor committee, divided into the Retinoblastoma and Infrequent Tumor subcommittees. The Infrequent Tumor subcommittee has traditionally included an emphasis on globally rare tumors such as adrenocortical carcinoma, nasopharyngeal carcinoma, or those tumors that are rare in young children, despite being common in adolescents and young adults, such as colorectal carcinoma, thyroid carcinoma, and melanoma. Pleuropulmonary blastoma, gonadal stromal tumors, pancreatic tumors including pancreatoblastoma, gastrointestinal stromal tumor, nonmelanoma skin cancers, neuroendocrine tumors, and desmoplastic small …
Assessment Of Myocardial Viability In Ischemic Cardiomyopathy-Scarred By The Data But Still Alive, Julio A. Panza
Assessment Of Myocardial Viability In Ischemic Cardiomyopathy-Scarred By The Data But Still Alive, Julio A. Panza
NYMC Faculty Publications
No abstract provided.
Standing Tests Lack Reliability To Diagnose All Adolescents Who Have Postural Tachycardia Syndrome, Julian M. Stewart, Paul Visintainer, Marvin S. Medow
Standing Tests Lack Reliability To Diagnose All Adolescents Who Have Postural Tachycardia Syndrome, Julian M. Stewart, Paul Visintainer, Marvin S. Medow
NYMC Faculty Publications
No abstract provided.
Utilization Of Hepatitis C Virus Infected Donors In Heart Transplant Recipients With Elevated Meld-Xi Score, Rahim Hirani, Kenji Okumura, Ameesh Isath, Vasiliki Gregory, Shazli Khan, Abhay Dhand, Gregg M. Lanier, David Spielvogel, Masashi Kai, Suguru Ohira
Utilization Of Hepatitis C Virus Infected Donors In Heart Transplant Recipients With Elevated Meld-Xi Score, Rahim Hirani, Kenji Okumura, Ameesh Isath, Vasiliki Gregory, Shazli Khan, Abhay Dhand, Gregg M. Lanier, David Spielvogel, Masashi Kai, Suguru Ohira
NYMC Faculty Publications
BACKGROUND: The advent of direct-acting antivirals has helped to increase the safe utilization of organs from hepatitis C virus positive (HCV+) donors. However, the outcomes of heart transplantation (HT) using an HCV+ donor are unclear in recipients with underlying liver disease represented by an elevated model for end-stage liver disease excluding international normalized ratio (MELD-XI). METHODS: The United Network of Organ Sharing database was queried from Jan 2016 to Dec 2021. Post-transplant outcomes stratified by recipient MELD-XI score (low <10.37, medium, 10.38-13.39, and high >13.4) was compared between patients with HT from HCV+ (N = 792) and patients with HT from HCV-negative donors (N = …
Extra-Cardiac Uptake Of 99mtc-Pyrophosphate Scan Leading To The Diagnosis Of Stage Iv Metastatic Prostatic Adenocarcinoma, Maharshi Raval, Sajid Siddiq
Extra-Cardiac Uptake Of 99mtc-Pyrophosphate Scan Leading To The Diagnosis Of Stage Iv Metastatic Prostatic Adenocarcinoma, Maharshi Raval, Sajid Siddiq
NYMC Faculty Publications
No abstract provided.
A Case Study On The Dermatoscopic Findings Of Darier's Disease In Skin Type Vi, Samavia Khan, Banu Farabi, Alina Zufall, Anjelica Peacock, Kenneth Helmandollar, Kenneth Shulman, Bijan Safai
A Case Study On The Dermatoscopic Findings Of Darier's Disease In Skin Type Vi, Samavia Khan, Banu Farabi, Alina Zufall, Anjelica Peacock, Kenneth Helmandollar, Kenneth Shulman, Bijan Safai
NYMC Faculty Publications
We present dermatoscopic findings of long-standing, untreated Darier's disease (DD) in skin type VI that differs from current findings in literature. Robust hyperkeratotic polygonal-shaped plugs without a surrounding white halo and classic vascular features were noted on the anterior scalp, neck, axilla, midline trunk, and extensors. Through this case, we aim to contribute to emerging literature in describing features of DD under dermatoscopy to augment diagnosis.
Quilting Suture Technique After Mastectomy: A Meta-Analysis, Eleni Drivas, Mahir Gachabayov, Agon Kajmolli, Zehavya Stadlan, Daniel Moritz Felsenreich, Maria Castaldi
Quilting Suture Technique After Mastectomy: A Meta-Analysis, Eleni Drivas, Mahir Gachabayov, Agon Kajmolli, Zehavya Stadlan, Daniel Moritz Felsenreich, Maria Castaldi
NYMC Faculty Publications
BACKGROUND: There is no level 1a evidence testing quilting suture (QS) technique after mastectomy on wound outcomes. The aim of this systematic review and meta-analysis evaluates QS and association with surgical site occurrences as compared to conventional closure (CC) for mastectomy. METHODS: MEDLINE, PubMed, and Cochrane Library were systematically searched to include adult women with breast cancer undergoing mastectomy. The primary endpoint was postoperative seroma rate. Secondary endpoints included rates of hematoma, surgical site infection (SSI), and flap necrosis. The Mantel-Haenszel method with random-effects model was used for meta-analysis. Number needed to treat was calculated to assess clinical relevance of …
Leukemic Retinopathy: A Diagnostic Clue For Initial Detection And Prognosis Of Leukemia, Tatyana Beketova, Emanuel Mordechaev, Brian Murillo, Max D. Schlesinger
Leukemic Retinopathy: A Diagnostic Clue For Initial Detection And Prognosis Of Leukemia, Tatyana Beketova, Emanuel Mordechaev, Brian Murillo, Max D. Schlesinger
NYMC Faculty Publications
Leukemia is a systemic malignancy that can compromise various physiological functions, including vision. We report a case of a 37-year-old male presenting with worsening bilateral central vision loss, fatigue, shortness of breath, and ankle edema. Ophthalmic examination revealed extensive retinal hemorrhages, Roth spots, and subhyaloid hemorrhages, consistent with leukemic retinopathy. Further hematologic workup confirmed chronic eosinophilic leukemia. The patient showed systemic and visual improvement after prompt treatment with imatinib. This case highlights the importance of ophthalmological assessment in diagnosing leukemia, as ocular manifestations may often be the first sign of hematological disease.
Still Not Safe? A Propensity Score Matched Analysis Of Colloid Use In Traumatic Brain Injury, Matthew Li, Ilya Shnaydman, David Samson, Jenna Littmann, Thejas Hiremath, Jia Sun, Alexandra J. Lee, Hannah Litwa, Caitlin M. Gaudio, Salvatore Affrunti, Anrew Villion
Still Not Safe? A Propensity Score Matched Analysis Of Colloid Use In Traumatic Brain Injury, Matthew Li, Ilya Shnaydman, David Samson, Jenna Littmann, Thejas Hiremath, Jia Sun, Alexandra J. Lee, Hannah Litwa, Caitlin M. Gaudio, Salvatore Affrunti, Anrew Villion
NYMC Faculty Publications
No abstract provided.
Nephrotic Syndrome Following Covid-19 Vaccination: A Systematic Review, Charmy Parikh, Henil Upadhyay, Suyog Patel, Ramaswamy Sundararajan, Dhairya Shah, Ayush Anand, Bhavana Baraskar, Tulsi Bhatt, Deepak Verma, Shubham Agrawal, Amol Mittal, Sanjeev Gupta
Nephrotic Syndrome Following Covid-19 Vaccination: A Systematic Review, Charmy Parikh, Henil Upadhyay, Suyog Patel, Ramaswamy Sundararajan, Dhairya Shah, Ayush Anand, Bhavana Baraskar, Tulsi Bhatt, Deepak Verma, Shubham Agrawal, Amol Mittal, Sanjeev Gupta
NYMC Faculty Publications
BACKGROUND: Severe acute respiratory syndrome coronavirus 2 infection has caused significant morbidity and mortality. Vaccines produced against this virus have proven highly effective. However, adverse events following vaccination have also been reported. One of them is nephrotic syndrome, that can be associated with different pathologic pictures. This review aims to provide a wider understanding of incidence, etiopathogenesis, and management of nephrotic syndrome following vaccination against SARS-CoV-2. METHODS AND RESULTS: A literature search was undertaken using appropriate keywords in various databases like PubMed, Google Scholar, Europe PMC, and Science Direct. Twenty-one articles were included following qualitative assessment. Data of 74 patients …
Intrasellar Hemorrhagic Chordoma Masquerading As Pituitary Apoplexy: Case Report And Review Of The Literature, Boyi Li, Michael G. Kim, Jose F. Dominguez, Eric Feldstein, George Kleinman, Fawaz Al-Mufti, Matthew Kim, Simon Hanft
Intrasellar Hemorrhagic Chordoma Masquerading As Pituitary Apoplexy: Case Report And Review Of The Literature, Boyi Li, Michael G. Kim, Jose F. Dominguez, Eric Feldstein, George Kleinman, Fawaz Al-Mufti, Matthew Kim, Simon Hanft
NYMC Faculty Publications
BACKGROUND AND IMPORTANCE: Chordomas are centrally located, expansile soft tissue neoplasms that arise from the remnants of the embryological notochord. Hemorrhagic presentation is exceedingly rare and can resemble pituitary apoplexy. Moreover, a purely intrasellar location of a chordoma is extremely uncommon. We report a case of a hemorrhagic intrasellar chordoma in an adult male, which presented similarly to pituitary apoplexy and was resolved with surgical resection. CLINICAL PRESENTATION: A 69-year-old male presented with a 4 week history of acute onset headache and concurrent diplopia, with significantly reduced testosterone and slightly reduced cortisol. His left eye demonstrated a sixth cranial nerve …
Dietary Patterns And Associated Lifestyle Factors Among University Students In Qatar, Sohaila Cheema, Patrick Maisonneuve, Amit Abraham, Karima Chaabna, Wajiha Yousuf, Tasnim Mushannen, Hania Ibrahim, Abdallah Tom, Albert B. Lowenfels, Ravinder Mamtani
Dietary Patterns And Associated Lifestyle Factors Among University Students In Qatar, Sohaila Cheema, Patrick Maisonneuve, Amit Abraham, Karima Chaabna, Wajiha Yousuf, Tasnim Mushannen, Hania Ibrahim, Abdallah Tom, Albert B. Lowenfels, Ravinder Mamtani
NYMC Faculty Publications
We aimed to investigate the association between university students' dietary patterns, their demographics and lifestyle in a cross-sectional study in Qatar. 370 students in eight universities in Qatar enrolled between February 2017 and February 2018. Based on a structured questionnaire, dietary patterns were identified using principal component analysis, and their associations with student characteristics were assessed using logistic regression. Four dietary patterns were identified. The 'fast food' pattern was associated with being younger and male (p-values ≤ 0.1). The 'traditional diet' pattern was associated with not skipping meals or eating when bored (p-values = 0.1). The 'healthy diet' pattern was …