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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Thomas Jefferson University

2014

Department of Neurosurgery Faculty Papers

Aneurysm rupture; anticoagulant therapy; artery reconstruction; brain hematoma; brain hemorrhage; brain ischemia; clinical effectiveness; device safety; drug substitution; drug withdrawal; endovascular aneurysm repair; equipment design; flow diversion method; human; intermethod comparison; intracranial aneurysm; morbidity; mortality; patient safety; pipeline embolization device; postoperative complication; review; self expanding stent; surgical technique; treatment indication; unruptured intracranial aneurysm

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Flow-Diversion Panacea Or Poison?, Mario Zanaty, Nohra Chalouhi, Md, Stavropoula I. Tjoumakaris, Robert H. Rosenwasswer Md, L. Fernando Gonzalez, Pascal Jabbour Md Feb 2014

Flow-Diversion Panacea Or Poison?, Mario Zanaty, Nohra Chalouhi, Md, Stavropoula I. Tjoumakaris, Robert H. Rosenwasswer Md, L. Fernando Gonzalez, Pascal Jabbour Md

Department of Neurosurgery Faculty Papers

Endovascular therapy is now the treatment of choice for intracranial aneurysms (IAs) for its efficacy and safety profile. The use of flow diversion (FD) has recently expanded to cover many types of IAs in various locations. Some institutions even attempt FD as first line treatment for unruptured IAs. The most widely used devices are the pipeline embolization device (PED), the SILK flow diverter (SFD), the flow redirection endoluminal device (FRED), and Surpass. Many questions were raised regarding the long-term complications, the optimal regimen of dual antiplatelet therapy, and the durability of treatment effect. We reviewed the literature to address these …