Medicine and Health Sciences Commons^™

Efficacy Of Morning-Only Compared With Split-Dose Polyethylene Glycol Electrolyte Solution For Afternoon Colonoscopy: A Randomized Controlled Single-Blind Study., Rebecca Matro, Md, Anastasia Shnitser, Md, Maya Spodik, Md, Constantine Daskalakis, Sc.D, Leo Katz, Md, Alexandra Murtha, Ba, David Kastenberg, Md

Division of Internal Medicine Faculty Papers & Presentations

OBJECTIVES: Administering a purgative close to the time of colonoscopy is optimal for cleansing. The aim of this study was to compare the efficacy and tolerability of morning-only (AM-only) polyethylene glycol electrolyte solution (PEG-ELS) to split-dose (PM/AM) PEG-ELS for afternoon colonoscopy.

METHODS: This was a single-center, prospective, randomized, investigator-blinded, non-inferiority study comparing AM-only to PM/AM PEG-ELS for afternoon outpatient colonoscopy. The primary end point was whole colon prep adequacy. Tolerance and polyp detection were secondary outcomes.

RESULTS: Overall, 125 patients were randomized and 9 withdrew without taking any prep. Of 116 analyzed, 62 received AM-only prep and 54 received PM/AM …

Pulmonary Hypertension Is A Frequent Event In Patients With Chronic Myeloid Leukemia Treated With Tyrosine Kinase Inhibitors, Sameh Gaballa, Aref Al-Kali, Hagop Kantarjian, Elias Jabbour, Alfonso Quintas-Cardama, Mohamad Ayoubi, Gautam Borthakur, S. M. O'Brien, J. E. Cortes

Division of Internal Medicine Faculty Papers & Presentations

Poster presented at American Society of Clinical Oncology in Chicago Illinois.

Background: Tyrosine kinase inhibitors (TKI) are the current standard therapy for patients with chronic myeloid leukemia (CML). Fluid retention and pleural effusions have been reported in patients treated with TKIs, particularly with dasatinib. Although TKIs have been shown to reverse pulmonary hypertension (PH) in animal models, there have been some reports of development of reversible PH with dasatinib.

Methods: We conducted a retrospective analysis on 401 patients diagnosed with CML in chronic phase (CP) who were treated with TKIs (imatinib, dasatinib, or nilotinib) as initial therapy for CML and …

Evaluation Of A Novel Method For Measuring Cea Levels From Pancreas Cyst Aspirates, Vinay K. Katukuri, Md, Darren Andrade, Md, David E. Loren, Md, Thomas E. Kowalski, Md

Division of Internal Medicine Faculty Papers & Presentations

Conclusions:

The novel commercial method of cyst fluid analysis allows for accurate measurement of cyst fluid CEA even on cyst fluid aspirates of less than 1ml, and potentially less than 100ul of fluid.

This measurement tool increases the yield of EUS FNA for pancreatic cysts, particularly for those in whom cyst fluid volumes are small.

By optimizing specimen handling, it is possible to satisfy information needs more effectively thereby contributing to more comprehensive and better diagnosis and management.

The Incidence, Severity And Distribution Of Colonic Bubbles After Bowel Preparation With Split Dose 2l Polyethylene Glycol-Electrolyte Solution With Sodium Sulfate, Sodium Ascorbate And Ascorbic Acid (Peg-Els): A Pilot Study, Carly Rubin, Constantine Daskalakis, Vicki Gordon, Rebecca Matro, David Kastenberg

Division of Internal Medicine Faculty Papers & Presentations

Conclusions:

1. Colonic bubbles that could interfere with polyp detection are present in 35% of patients receiving split dose PEG-ELS.

2. Most bubbles occur in the right and transverse colon.

3. Advanced age is an independent risk for bubbles.