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Articles 1 - 5 of 5
Full-Text Articles in Medicine and Health Sciences
Tgf-Beta1 In Aplysia: Role In Long-Term Changes In The Excitability Of Sensory Neurons And Distribution Of Tbetar-Ii-Like Immunoreactivity, J Chin, A Angers, L J. Cleary, A Eskin, J H. Byrne
Tgf-Beta1 In Aplysia: Role In Long-Term Changes In The Excitability Of Sensory Neurons And Distribution Of Tbetar-Ii-Like Immunoreactivity, J Chin, A Angers, L J. Cleary, A Eskin, J H. Byrne
Journal Articles
Exogenous recombinant human transforming growth factor beta-1 (TGF-beta1) induced long-term facilitation of Aplysia sensory-motor synapses. In addition, 5-HT-induced facilitation was blocked by application of a soluble fragment of the extracellular portion of the TGF-beta1 type II receptor (TbetaR-II), which presumably acted by scavenging an endogenous TGF-beta1-like molecule. Because TbetaR-II is essential for transmembrane signaling by TGF-beta, we sought to determine whether Aplysia tissues contained TbetaR-II and specifically, whether neurons expressed the receptor. Western blot analysis of Aplysia tissue extracts demonstrated the presence of a TbetaR-II-immunoreactive protein in several tissue types. The expression and distribution of TbetaR-II-immunoreactive proteins in the central …
A Cbfa1-Dependent Genetic Pathway Controls Bone Formation Beyond Embryonic Development, P Ducy, M Starbuck, M Priemel, J Shen, G Pinero, V Geoffroy, M Amling, G Karsenty
A Cbfa1-Dependent Genetic Pathway Controls Bone Formation Beyond Embryonic Development, P Ducy, M Starbuck, M Priemel, J Shen, G Pinero, V Geoffroy, M Amling, G Karsenty
Journal Articles
The molecular mechanisms controlling bone extracellular matrix (ECM) deposition by differentiated osteoblasts in postnatal life, called hereafter bone formation, are unknown. This contrasts with the growing knowledge about the genetic control of osteoblast differentiation during embryonic development. Cbfa1, a transcriptional activator of osteoblast differentiation during embryonic development, is also expressed in differentiated osteoblasts postnatally. The perinatal lethality occurring in Cbfa1-deficient mice has prevented so far the study of its function after birth. To determine if Cbfa1 plays a role during bone formation we generated transgenic mice overexpressing Cbfa1 DNA-binding domain (DeltaCbfa1) in differentiated osteoblasts only postnatally. DeltaCbfa1 has a higher …
Predicting The Risk Of Obesity Using A Bayesian Network, Christopher C. Bunn, Min Du, Keyi Niu, Todd R. Johnson, Walker S. Poston, John P. Foreyt
Predicting The Risk Of Obesity Using A Bayesian Network, Christopher C. Bunn, Min Du, Keyi Niu, Todd R. Johnson, Walker S. Poston, John P. Foreyt
Journal Articles
No abstract provided.
Web Browser Implements Unobtrusive Randomized Comparisons Of Instruction In Health Informatics Classroom, Craig W. Johnson
Web Browser Implements Unobtrusive Randomized Comparisons Of Instruction In Health Informatics Classroom, Craig W. Johnson
Journal Articles
No abstract provided.
Intelligent Support Of Gait Analysis, Kathy A. Johnson, Sheldon R. Simon, Philip J. Smith, Jack W. Smith
Intelligent Support Of Gait Analysis, Kathy A. Johnson, Sheldon R. Simon, Philip J. Smith, Jack W. Smith
Journal Articles
No abstract provided.