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Full-Text Articles in Medicine and Health Sciences

The Protective Effect Of Capparis Ovata In Acute Hepatotoxicity Induced By Paracetamol, Nurcan Doğan, Mustafa Akçam, Tuğba Koca, Duygu Kumbul Doğuç, Meltem Özgöçmen Jan 2016

The Protective Effect Of Capparis Ovata In Acute Hepatotoxicity Induced By Paracetamol, Nurcan Doğan, Mustafa Akçam, Tuğba Koca, Duygu Kumbul Doğuç, Meltem Özgöçmen

Turkish Journal of Medical Sciences

Background/aim: To investigate the efficiency of Capparis ovata as a protective agent against acute paracetamol toxicity of the liver. Materials and methods: A total of 36 Wistar albino rats were divided into 4 groups: 1) paracetamol, 2) Capparis ovata + paracetamol, 3) Capparis ovata, and 4) control. Groups 2 and 3 were given Capparis ovata and Groups 1 and 4 distilled water for 8 days. On day 8, 3000 mg kg-1 paracetamol was administered orally to Groups 1 and 2. Samples were taken on day 9. AST, ALT, total bilirubin, direct bilirubin, GGT, and ALP levels were assessed. Lipid peroxidation …


The Antioxidant And Antimutagenic Activities Of Ankaferd Blood Stopper,A Natural Hemostatic Agent Used In Dentistry, Aysel Uğur, Nurdan Saraç, Di̇lek Aynur Çankal, Murat Özle Jan 2016

The Antioxidant And Antimutagenic Activities Of Ankaferd Blood Stopper,A Natural Hemostatic Agent Used In Dentistry, Aysel Uğur, Nurdan Saraç, Di̇lek Aynur Çankal, Murat Özle

Turkish Journal of Medical Sciences

Background/aim: This study investigated the antioxidant and antimutagenic properties of Ankaferd blood stopper (ABS), a plant-based topical hemostatic agent used in Turkey to treat external hemorrhages and bleeding during dental surgery. While previous studies have examined the antimicrobial, antiinflammatory, and anticarcinogenic properties of ABS, to our knowledge, this is the first study to report on the antioxidant and antimutagenic activities of this drug. Materials and methods: Antioxidant activity was evaluated using DPPH radical-scavenging and β-carotene-linoleic acid tests. Antimutagenic activity was assessed using the Ames Salmonella/microsome mutagenicity test with the bacterial mutant strains Salmonella typhimurium TA98 and TA100. Results: Although ABS …


Prospects Of Curcumin As An Additive In Storage Solutions: A Study On Erythrocytes, Soumya Ravikumar, Carl Hsieh, Vani Rajashekharaiah Jan 2016

Prospects Of Curcumin As An Additive In Storage Solutions: A Study On Erythrocytes, Soumya Ravikumar, Carl Hsieh, Vani Rajashekharaiah

Turkish Journal of Medical Sciences

Background/aim: Curcumin, a naturally occurring antioxidant, shows a wide variety of medicinal properties. The possibility of utilizing curcumin as an additive in storage solutions of blood has not been explored. The purpose of this study was to analyze the effect of curcumin on erythrocytes during storage. Materials and methods: Blood obtained from rats was stored (4 °C) for 20 days in citrate-phosphate-dextrose-adenine-1 solution. Samples were divided into four groups: 1) Controls; 2) Curcumin 10 mM; 3) Curcumin 30 mM; and 4) Curcumin 60 mM. Every fifth day, hemoglobin, superoxide, antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase (GSH-Px)), lipid peroxidation …


Effect Of Dietary Orange Peel Extract On Physiological, Biochemical, And Metabolic Responses Of Japanese Quail Reared Under Low Ambient Temperature, Mehmet Çi̇ftçi̇, Ülkü Gülci̇han Şi̇mşek, Bestami̇ Dalkiliç, Mehmet Ali̇ Azman, Ökkeş Yilmaz, Seda İflazoğlu Mutlu, Mehtap Özçeli̇k, Yasi̇n Baykalir, Fadi̇me Tonbak, Muammer Bahşi̇ Jan 2016

Effect Of Dietary Orange Peel Extract On Physiological, Biochemical, And Metabolic Responses Of Japanese Quail Reared Under Low Ambient Temperature, Mehmet Çi̇ftçi̇, Ülkü Gülci̇han Şi̇mşek, Bestami̇ Dalkiliç, Mehmet Ali̇ Azman, Ökkeş Yilmaz, Seda İflazoğlu Mutlu, Mehtap Özçeli̇k, Yasi̇n Baykalir, Fadi̇me Tonbak, Muammer Bahşi̇

Turkish Journal of Veterinary & Animal Sciences

The effects of dietary orange peel extract (OPE) supplementation on growth performance, carcass traits, serum biochemical parameters, antioxidant status of tissues, and fatty acid composition of breast meat in Japanese quails reared under low ambient temperature were investigated in the present study. A total of 108 quails of 15 days old were assigned to 3 groups with 3 replicates. Animals were fed with a corn/soy-based standard diet in the control group and a standard diet supplemented with either 100 or 200 ppm of OPE in the experimental groups (control, OPE-100, and OPE-200 groups, respectively). Room temperature was gradually lowered at …