Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 8 of 8
Full-Text Articles in Medicine and Health Sciences
The Effect Of Pentylenetetrazole-Induced Seizures On Blood-Brain Barrier Integrity In A Rat Model Of Preeclampsia, Mutlu Küçük, Mehmet Kaya, Nurcan Orhan, Oğuzhan Eki̇zoğlu, Erol Arslan, Nadi̇r Arican, Rabi̇a Candan Gürses, İmdat Elmas, Ri̇vaze Kalayci, Bülent Ahishali
The Effect Of Pentylenetetrazole-Induced Seizures On Blood-Brain Barrier Integrity In A Rat Model Of Preeclampsia, Mutlu Küçük, Mehmet Kaya, Nurcan Orhan, Oğuzhan Eki̇zoğlu, Erol Arslan, Nadi̇r Arican, Rabi̇a Candan Gürses, İmdat Elmas, Ri̇vaze Kalayci, Bülent Ahishali
Turkish Journal of Veterinary & Animal Sciences
The pathophysiological mechanisms underlying blood-brain barrier (BBB) disruption in preeclampsia/eclampsia have not been elucidated. This study investigated the effect of pentylenetetrazole (PTZ)-induced seizures on the functional and structural properties of the BBB during N (omega)-nitro-L-arginine methyl ester (L-NAME)-induced hypertension and proteinuria in pregnant rats. Animals were treated with L-NAME for 10 days, beginning on day 10 of pregnancy. The BBB permeability was determined by measurements of sodium fluorescein (NaFlu) extravasation into the brain. Occludin and aquaporin (AQP)-4 immunoreactivities were evaluated in brain sections. Severe proteinuria and significantly increased arterial blood pressure were observed following L-NAME treatment. PTZ-induced seizures in pregnant …
Fecal Progesterone Analysis For Monitoring Reproductive Status In Dairy Goats, Amelia Miranda Morgiana Jack, Chao-Chin Chang, Huo-Cheng Peh, Jacky Peng-Wen Chan
Fecal Progesterone Analysis For Monitoring Reproductive Status In Dairy Goats, Amelia Miranda Morgiana Jack, Chao-Chin Chang, Huo-Cheng Peh, Jacky Peng-Wen Chan
Turkish Journal of Veterinary & Animal Sciences
The present study was undertaken to evaluate the use of fecal progesterone (FP_4) concentration for early pregnancy diagnosis, estrus detection, and predicting the litter size and parturition date in dairy goats. Fecal samples were collected from 17 hand-mated goats 3 times a week for 22-23 weeks, beginning on the day of mating. The levels of FP_4 were determined by enzyme-linked immunosorbent assay (ELISA). Significant positive correlations were found between the levels of serum P_4 and FP_4 (r = 0.8787, n = 13). Pregnancy diagnosis was performed at 2 months postmating with transabdominal ultrasonography and confirmed upon birth of the offspring. …
Iodine Deficiency In Pregnancy And In Women Of Reproductive Age In Erzurum, Turkey, Kadi̇r Çeti̇nkaya, Meti̇n İngeç, Semra Çeti̇nkaya, İbrahi̇m Kaplan
Iodine Deficiency In Pregnancy And In Women Of Reproductive Age In Erzurum, Turkey, Kadi̇r Çeti̇nkaya, Meti̇n İngeç, Semra Çeti̇nkaya, İbrahi̇m Kaplan
Turkish Journal of Medical Sciences
Aim: Iodine deficiency (ID) is an important public health problem and the most common cause of preventable mental retardation. The aims of this study were to determine the urinary iodine concentration (UIC) of pregnant women living in Erzurum, to assess the ID rate, and to find out whether iodine supplementation is necessary in pregnancy. Materials and methods: Spot urine was obtained from pregnant and nonpregnant women with no functional or organic thyroid disease. The UIC was studied using the Sandell-Kolthoff method. Results: The median UIC values of pregnant women in the first, second, and third trimesters and of the nonpregnant …
Maternal Smoking During Pregnancy And Effects On Neonatal Anthropometry: A Prospective Study, Fati̇h Bolat, Özge Eren, Güher Bolat, Emrah Can, Serdar Cömert, Hasan Si̇nan Uslu, Asi̇ye Nuhoğlu
Maternal Smoking During Pregnancy And Effects On Neonatal Anthropometry: A Prospective Study, Fati̇h Bolat, Özge Eren, Güher Bolat, Emrah Can, Serdar Cömert, Hasan Si̇nan Uslu, Asi̇ye Nuhoğlu
Turkish Journal of Medical Sciences
To identify risk factors associated with cigarette smoking during pregnancy and to evaluate the effect of smoking on anthropometric measurements. Materials and methods: This study was carried out prospectively in selected women who gave birth to a healthy, term infant at Şişli Etfal Education and Research Hospital from January 2009 to January 2010. Smoking status during pregnancy was categorized into 3 groups: nonsmoker; smoker; passive smoker. Regression analysis was performed to compare risk factors with cigarette smoking. Results: A total of 1175 mothers were enrolled. Active and passive smoking rates were 14.9% and 32.3%, respectively. In univariate analysis, maternal active …
Sigmoid Volvulus In Pregnancy, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk
Sigmoid Volvulus In Pregnancy, Sabri̇ Selçuk Atamanalp, Gürkan Öztürk
Turkish Journal of Medical Sciences
To review the clinical outcomes of 9 patients with sigmoid volvulus (SV), a rare complication during pregnancy. Materials and methods: The clinical records of the patients were reviewed retrospectively. Results: The age range of the patients was 24-39 years (mean: 30.6 years). All patients were multiparous, and 6 patients (66.7%) were in the third trimester when diagnosed with SV. The main clinical features were abdominal pain/tenderness, obstipation, and distention in all patients (100.0%). The correct diagnosis was achieved based on clinical examination in 66.7% of the cases. Endoscopic detorsion was attempted in 6 patients (66.7%), with an 83.3% success rate. …
Mean Platelet Volume As A Marker Of Future Cardiovascular Disease Risk In Pregnant Women With Impaired Fasting Glucose And Impaired Glucose Tolerance, Nermi̇n Köşüş, Aydin Köşüş, Ni̇lgün Turhan
Mean Platelet Volume As A Marker Of Future Cardiovascular Disease Risk In Pregnant Women With Impaired Fasting Glucose And Impaired Glucose Tolerance, Nermi̇n Köşüş, Aydin Köşüş, Ni̇lgün Turhan
Turkish Journal of Medical Sciences
To compare the mean platelet volume (MPV) of pregnant women with mild glycemic disorders with that of healthy pregnant women to find whether these disorders are risk factors for future cardiovascular disease. Materials and methods: Fasting blood glucose and 50-g oral glucose loading were measured. A 100-g, 3-h oral glucose tolerance test was done when plasma glucose was ≥140 mg/dL, following a loading test. According to the test results, 4 groups were formed: control, impaired fasting glucose, false positive loading test, and impaired glucose tolerance. The hematologic parameters were compared in all of the groups. Results: The mean MPV of …
Ileosigmoid Knotting In Pregnancy, Sabri̇ Selçuk Atamanalp
Ileosigmoid Knotting In Pregnancy, Sabri̇ Selçuk Atamanalp
Turkish Journal of Medical Sciences
Aim: Ileosigmoid knotting (ISK) is a rare event in pregnancy. This study reviewed the clinical outcomes of 3 pregnant patients with ISK and compared the characteristics of these pregnant women with 16 nonpregnant women. Materials and methods: The clinical records were reviewed retrospectively. Results: Three pregnant patients accounted for 4.2% of 72 total ISK patients and 15.8% of 19 female ISK patients. The ages of the patients were 35, 38, and 31 years (mean: 34.7 years). All of the patients were multiparous. Two patients (66.7%) were in the 3rd trimester and 1 (33.3%) was in the 2nd trimester. The mean …
Effect Of Prenatal Exposure To Cigarette Smoke On The Conduction Of Sensory Nerve Fibers In The Rat, Jumah Shakhanbeh
Effect Of Prenatal Exposure To Cigarette Smoke On The Conduction Of Sensory Nerve Fibers In The Rat, Jumah Shakhanbeh
Turkish Journal of Medical Sciences
Aim: To investigate the effect of prenatal exposure to cigarette smoke (CS) on the conduction of sensory nerve fibers in the adult rat offspring. Materials and methods: Pregnant rats were exposed to CS by inhalation during the gestation period. The saphenous nerve in the adult offspring was exposed in vivo, and the conduction parameters of the threshold, maximum strength of stimulation, conduction velocity, and amplitude of compound action potentials (CAPs) of A\alpha\beta-, A\delta-, and C-fibers were examined. Results: Prenatal exposure to CS induced significant reduction (P < 0.005) in the peak amplitude of CAPs of A\alpha\beta- and A\delta-fibers. The conduction velocity of A\alpha\beta-fibers and C-fibers was significantly (P < 0.025-0.05) increased after prenatal exposure to CS. Conclusion: Prenatal exposure to CS attenuates the conduction of sensory nerve fibers in the rat saphenous nerve.