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Sensitization To Food And Inhalant Allergens In Healthy Children In Van, East Turkey, Mehmet Parlak, Ayteki̇n Çikman, Yasemi̇n Bayram, Nesri̇n Ceylan, Ulaş Çalişir, Mustafa Berktaş Jan 2016

Sensitization To Food And Inhalant Allergens In Healthy Children In Van, East Turkey, Mehmet Parlak, Ayteki̇n Çikman, Yasemi̇n Bayram, Nesri̇n Ceylan, Ulaş Çalişir, Mustafa Berktaş

Turkish Journal of Medical Sciences

Background/aim: The purpose of this study was to determine the most frequent food and inhalant allergens leading to allergic sensitization in children in Van Province of Turkey. Materials and methods: The study included 1052 serum samples with no diagnosis of allergy. The sera were tested with the Euroline Pediatric IgE test kit (EUROIMMUN, Germany). By using the EUROLineScan digital evaluation system, the intensity of bands was calculated with enzyme allergosorbent test classification. Results: Out of the 1052 tested sera, 143 were found to be cross-reactive carbohydrate determinant-positive and were discarded from the study. Of the remaining 909 sera, 513 (56%) …


Comparison Of Nasal Senses Following Open And Closed Rhinoplasty, Mehmet İhsan Okur, Onur Gökdemi̇r, Necmetti̇n Karasu, Alpagan Mustafa Yildirim Jan 2016

Comparison Of Nasal Senses Following Open And Closed Rhinoplasty, Mehmet İhsan Okur, Onur Gökdemi̇r, Necmetti̇n Karasu, Alpagan Mustafa Yildirim

Turkish Journal of Medical Sciences

Background/aim: The objective of this study was to compare the postoperative changes taking place in the nasal senses of patients who underwent a rhinoplasty through the open or closed incision method. Materials and methods: In a prospective study, 15 patients had a closed rhinoplasty surgery and 15 others had an open one. By pinpointing 9 spots in the nose, a sensory assessment was made by means of Semmes-Weinstein monofilaments prior to the surgery and 1 week and 1, 3, and 6 months after the surgery. Results: In the open and closed groups, there was hypoesthesia 1 week after the surgery …


How To Close Open Choledochotomy: Primary Closure, Primary Closurewith T-Tube Drainage, Or Choledochoduodenostomy?, Bülent Aydinli, Gürkan Öztürk, Sabri̇ Selçuk Atamanalp, Bünyami̇ Özoğul, Şükrü Arslan, Ercan Korkut, Abdullah Kisaoğlu, Abdulmeci̇t Kantarci, Rüstem Berhan Pi̇ri̇moğlu, Mehmet İlhan Yildirgan, Nurhak Aksungur Jan 2016

How To Close Open Choledochotomy: Primary Closure, Primary Closurewith T-Tube Drainage, Or Choledochoduodenostomy?, Bülent Aydinli, Gürkan Öztürk, Sabri̇ Selçuk Atamanalp, Bünyami̇ Özoğul, Şükrü Arslan, Ercan Korkut, Abdullah Kisaoğlu, Abdulmeci̇t Kantarci, Rüstem Berhan Pi̇ri̇moğlu, Mehmet İlhan Yildirgan, Nurhak Aksungur

Turkish Journal of Medical Sciences

Background/aim: Although common bile duct stones are generally treated endoscopically, surgery is required if endoscopic removal is impossible. The aim of this study was to compare the surgical options in such patients. Materials and methods: A total of 282 patients with common bile duct stones underwent open choledochotomy; primary closure was applied in 48 (17.0%), primary closure with T-tube drainage in 81 (28.7%), and choledochoduodenostomy in 153 (54.3%) patients. Results: Postoperative complications were seen in 8 (16.7%) patients in the primary closure, 33 (40.7%) patients in the primary closure with T-drainage, and 37 (24.2%) patients in the choledochoduodenostomy group. No …


The Effect Of Hip And Knee Exercises On Pain, Function, And Strength In Patientswith Patellofemoral Pain Syndrome: A Randomized Controlled Trial, Mehtap Şahi̇n, Fi̇kri̇ye Fi̇gen Ayhan, Pinar Borman, Hüseyi̇n Atasoy Jan 2016

The Effect Of Hip And Knee Exercises On Pain, Function, And Strength In Patientswith Patellofemoral Pain Syndrome: A Randomized Controlled Trial, Mehtap Şahi̇n, Fi̇kri̇ye Fi̇gen Ayhan, Pinar Borman, Hüseyi̇n Atasoy

Turkish Journal of Medical Sciences

Background/aim: The role of hip muscles in the rehabilitation of patellofemoral pain syndrome has recently received interest. The aim of this study was to compare the efficiencies of hip exercises alongside knee exercises versus only knee exercises on pain, function, and isokinetic muscle strength in patients with this syndrome. Materials and methods: Fifty-five young female patients (mean age: 34.1 ± 6.2 years; mean BMI: 25.9 ± 3.9 kg/m2) with patellofemoral pain syndrome were included. The patients were randomized into groups of hip-and-knee exercises and knee-only exercise programs for 6 weeks with a total of 30 sessions at the clinic. Both …


Is The Nexfin Finger Cuff Method For Cardiac Output Measurement Reliableduring Coronary Artery Bypass Grafting? A Prospective Comparison With The Echocardiography And Flotrac/Vigileo Methods, Cem Aritürk, Meltem Açil, Hali̇m Ulugöl, Zehra Serpi̇l Ustalar Özgen, Eyüp Murat Ökten, Si̇nan Dağdelen, Eşref Hasan Karabulut, Hüseyi̇n Cem Alhan, Fevzi̇ Toraman Jan 2016

Is The Nexfin Finger Cuff Method For Cardiac Output Measurement Reliableduring Coronary Artery Bypass Grafting? A Prospective Comparison With The Echocardiography And Flotrac/Vigileo Methods, Cem Aritürk, Meltem Açil, Hali̇m Ulugöl, Zehra Serpi̇l Ustalar Özgen, Eyüp Murat Ökten, Si̇nan Dağdelen, Eşref Hasan Karabulut, Hüseyi̇n Cem Alhan, Fevzi̇ Toraman

Turkish Journal of Medical Sciences

Background/aim: The aim of the current study was to assess the accuracy of cardiac output (CO) measurements obtained by the Nexfin finger cuff method as compared with the FloTrac/Vigileo and echocardiography methods in coronary artery bypass grafting (CABG) patients. Materials and methods: First-time elective CABG patients were prospectively enrolled in this study and divided into three groups according to CO measurement method. CO measurements were performed simultaneously by three different contributors and were collected by the fourth one 24 h postoperative in the intensive care unit (ICU). Data were statistically analyzed. Results: Seventeen female and 13 male patients between 42 …


Effect Of Exposure To Violence On The Development Of Burnoutsyndrome In Ambulance Staff, Turgut Deni̇z, Meral Saygun, Oğuz Eroğlu, Hüseyi̇n Ülger, Burcu Azapoğlu Jan 2016

Effect Of Exposure To Violence On The Development Of Burnoutsyndrome In Ambulance Staff, Turgut Deni̇z, Meral Saygun, Oğuz Eroğlu, Hüseyi̇n Ülger, Burcu Azapoğlu

Turkish Journal of Medical Sciences

Background/aim: The aim of this study is to determine the condition of ambulance staff (AS) who have been exposed to any kind of violence and to predict risk of development of burnout syndrome. Materials and methods: Our study was performed with 120 AS working for the Kırıkkale Ambulance Services. During the research, questionnaires collecting descriptive information and the extent of violence to which the AS were exposed were administered; participants were asked to fill out the questionnaire themselves. Results: It was found that 81 (67.5%) participants had been subjected to at least one type of violence (verbal or physical). Sixty-two …


The Role Of Human Papilloma Virus And Herpes Viruses In The Etiology Of Nasal Polyposis, Mücahi̇de Esra Koçoğlu, Firat Zafer Mengeloğlu, Tayfun Apuhan, Şeyda Özsoy, Beyhan Yilmaz Jan 2016

The Role Of Human Papilloma Virus And Herpes Viruses In The Etiology Of Nasal Polyposis, Mücahi̇de Esra Koçoğlu, Firat Zafer Mengeloğlu, Tayfun Apuhan, Şeyda Özsoy, Beyhan Yilmaz

Turkish Journal of Medical Sciences

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Retinopathy Of Prematurity: Incidence, Risk Factors, And Evaluation Of Screening Criteria, Arzu Gebeşçe, Haşi̇m Uslu, Esengül Keleş, Aydin Yildirim, Bülent Gürler, Hamza Yazgan, Bülent Baştürk, Mehmet Demi̇rdöven, Alparslan Tonbul Jan 2016

Retinopathy Of Prematurity: Incidence, Risk Factors, And Evaluation Of Screening Criteria, Arzu Gebeşçe, Haşi̇m Uslu, Esengül Keleş, Aydin Yildirim, Bülent Gürler, Hamza Yazgan, Bülent Baştürk, Mehmet Demi̇rdöven, Alparslan Tonbul

Turkish Journal of Medical Sciences

Background/aim: The goal of this study was to investigate the incidence of retinopathy of prematurity (ROP) and the relationship between risk factors and disease in premature newborns in our neonatal intensive care unit. Materials and methods: A total of 219 premature subjects were retrospectively evaluated for retinopathy. Demographic information, clinical data, and risk factors were reviewed. Results: The gestational ages of the infants included in the study ranged between 25 and 36 weeks, and the birth weights ranged between 670 and 4460 g. In this study, the incidence of ROP was 20.1% (44) in preterm infants: 16 had stage 1 …


Intraoperative Application Of 5-Fluorouracil And Mitomycin C Aschemoadjuvants In Primary Pterygium Surgery, Yeşi̇m Altay, Özgür Balta Jan 2016

Intraoperative Application Of 5-Fluorouracil And Mitomycin C Aschemoadjuvants In Primary Pterygium Surgery, Yeşi̇m Altay, Özgür Balta

Turkish Journal of Medical Sciences

Background/aim: To compare the effectiveness of intraoperative 5 fluorouracil (5-FU) and mitomycin C (MMC) application in preventing recurrence following primary pterygium excision. Materials and methods: This was a prospective clinical trial that included 93 patients with primary pterygia assigned to three treatment groups in which 29 patients received an intraoperative application of 25 mg/mL 5-FU for 5 min, 32 patients received an intraoperative application of 0.02% MMC for 5 min, and 32 patients underwent only surgical excision (the control group). Follow-up visits were done on postoperative days 1, 3, 7, 15, and 30, and then every month. Results: After a …


Comparison Of Galactomannan, Beta-D-Glucan, And Aspergillus Dna In Sera Of High-Risk Adult Patients With Hematological Malignancies For The Diagnosis Of Invasive Aspergillosis, Gülçi̇n Bölük, Esra Kazak, Fahi̇r Özkalemkaş, Beyza Ener, Hali̇s Akalin, Harun Ağca, Yildiz Okuturlar, Kürşad Keski̇n, Başak Burgazlioğlu, Ridvan Ali̇ Jan 2016

Comparison Of Galactomannan, Beta-D-Glucan, And Aspergillus Dna In Sera Of High-Risk Adult Patients With Hematological Malignancies For The Diagnosis Of Invasive Aspergillosis, Gülçi̇n Bölük, Esra Kazak, Fahi̇r Özkalemkaş, Beyza Ener, Hali̇s Akalin, Harun Ağca, Yildiz Okuturlar, Kürşad Keski̇n, Başak Burgazlioğlu, Ridvan Ali̇

Turkish Journal of Medical Sciences

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Fully Automated Morphological Analysis Of Patients With Obstructive Sleep Apnea, Oktay Alğin, Burak Akin, Gökhan Ocakoğlu, Evri̇m Özmen Jan 2016

Fully Automated Morphological Analysis Of Patients With Obstructive Sleep Apnea, Oktay Alğin, Burak Akin, Gökhan Ocakoğlu, Evri̇m Özmen

Turkish Journal of Medical Sciences

Background/aim: Obstructive sleep apnea syndrome (OSAS) is a disease characterized by episodic hypoxia. We aimed to use the Freesurfer program for global evaluation of morphological changes in OSAS patients. Materials and methods: Three-dimensional T1-weighted images were obtained, and intracranial morphology was assessed in 18 patients with OSAS and 20 controls. Results of the volume and the cortical thickness analyses of both groups were compared statistically. Results: The total cortical, left-right hemispheres gray matter (GM), corpus callosum, and total GM volumes were lower in OSAS patients when compared with the control group (P < 0.001). The average cortical thickness was lower in OSAS patients bilaterally in pars orbitalis, paracentral, rostral middle frontal, middle frontal, orbital, and superior frontal gyri when compared with the control group (P < 0.05). Furthermore, the volume and average cortical thickness of multiple anatomic regions, apart from the brain parts mentioned above, were decreased unilaterally (e.g., hippocampus, cingulum, putamen, thalamus) in OSAS patients (P < 0.05). Conclusion: Multiple morphologic changes occur in the cerebral structures of OSAS patients due to intermittent ischemia episodes. Detection of those areas with Freesurfer is easier. New studies with large series would be needed for these subjects.


The Role Of Fdg Pet/Ct In Detection Of Distant Metastasis In Theinitial Staging Of Breast Cancer, Anar Aliyev, Sabi̇re Yilmaz Aksoy, Meftune Özhan, Özgül Ekmekçi̇oğlu, Betül Vatankulu, Pinar Çi̇ğdem Kocael, Muhammet Sai̇t Sağer, Meli̇h Engi̇n Erkan, Keri̇m Sönmezoğlu, Meti̇n Halaç Jan 2016

The Role Of Fdg Pet/Ct In Detection Of Distant Metastasis In Theinitial Staging Of Breast Cancer, Anar Aliyev, Sabi̇re Yilmaz Aksoy, Meftune Özhan, Özgül Ekmekçi̇oğlu, Betül Vatankulu, Pinar Çi̇ğdem Kocael, Muhammet Sai̇t Sağer, Meli̇h Engi̇n Erkan, Keri̇m Sönmezoğlu, Meti̇n Halaç

Turkish Journal of Medical Sciences

Background/aim: We aimed to evaluate the role of FDG PET/CT in the detection of extraaxillary regional nodal/distant metastasis in breast cancer patients and to assess the value of FDG PET/CT for detecting distant metastases in patient subgroups. Materials and methods: A total of 254 patients with breast cancer (248 female, 6 male) who underwent PET/CT for initial staging were enrolled. Patients were divided into four groups: Group 1 consisted of 154 patients diagnosed by tru-cut/core/FNAB, Group 2 comprised 32 patients diagnosed by excisional biopsy, Group 3 included 62 patients who had mastectomy-axillary lymph node dissection, and Group 4 consisted of …


Association Analysis Of Five Snp Variants With Gout In The Minnan Population In China, Chenna Zheng, Huiyong Yang, Qingyao Wang, Huachun Rao, Yong Diao Jan 2016

Association Analysis Of Five Snp Variants With Gout In The Minnan Population In China, Chenna Zheng, Huiyong Yang, Qingyao Wang, Huachun Rao, Yong Diao

Turkish Journal of Medical Sciences

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Does The Course Of Laboratory Parameters Help Us To Predict The Outcome Of Cchf?, Sümeyye Kazancioğlu, Esragül Akinci, Ali̇ye Baştuğ, Bi̇rcan Kayaaslan, Ayşe But, Hali̇de Aslaner, Seli̇m Sirri Eren, Meltem Arzu Yetki̇n, Hurrem Bodur Jan 2016

Does The Course Of Laboratory Parameters Help Us To Predict The Outcome Of Cchf?, Sümeyye Kazancioğlu, Esragül Akinci, Ali̇ye Baştuğ, Bi̇rcan Kayaaslan, Ayşe But, Hali̇de Aslaner, Seli̇m Sirri Eren, Meltem Arzu Yetki̇n, Hurrem Bodur

Turkish Journal of Medical Sciences

Abstrat Background/aim: This study was performed to identify the characteristics distinguishing fatal and nonfatal cases of patients diagnosed with Crimean-Congo hemorrhagic fever (CCHF). Materials and methods: A total of 92 patients with confirmed diagnosis of CCHF in 2009-2013 were included in the study. Results: A high level of urea and aPTT on the third day of hospital stay, diarrhea, somnolence, and the interval from the beginning of the symptoms to hospital admission were independently associated with fatality. Each 10-unit increase in aPTT and urea levels increased the fatality rate by 3.379-fold and 1.236-fold, respectively. Delay in hospital admission increased the …


Prevalence And Related Factors Of Psoriasis And Seborrheic Dermatitis: A Community Based Study, Yalçin Baş, Havva Yildiz Seçki̇n, Göknur Kalkan, Zennure Takci, Riza Çitil, Yalçin Önder, Şafak Şahi̇n, Ayşe Kevser Demi̇r Jan 2016

Prevalence And Related Factors Of Psoriasis And Seborrheic Dermatitis: A Community Based Study, Yalçin Baş, Havva Yildiz Seçki̇n, Göknur Kalkan, Zennure Takci, Riza Çitil, Yalçin Önder, Şafak Şahi̇n, Ayşe Kevser Demi̇r

Turkish Journal of Medical Sciences

No abstract provided.


Serological Prevalence Of Human Parvovirus B19 In Diseases Or Disordersrelated To Different Human Body Systems, Osman Aktaş, Hakan Aydin, Hakan Uslu Jan 2016

Serological Prevalence Of Human Parvovirus B19 In Diseases Or Disordersrelated To Different Human Body Systems, Osman Aktaş, Hakan Aydin, Hakan Uslu

Turkish Journal of Medical Sciences

Background/aim: Human parvovirus B19 is a pathogen that affects different parts of the body. We planned this study because of the lack of data on B19 seroprevalence based on different body-system diseases. Materials and methods: The prevalence of parvovirus B19 antibodies was investigated retrospectively in 1239 patients by review of medical records from 2009-2012, according to their diseases classified under general titles in compliance with the International Classification of Diseases (ICD-10). Parvovirus B19-specific antibodies were detected by quantitative enzyme immunoassays. Results: The positivity rate was 27.8% for only IgG, 8.5% for only IgM, and 2.6% for both IgG and IgM. …


Determination Of Regional Screening Criteria For Retinopathy Ofprematurity In The Eastern Black Sea Region Of Turkey, Mehmet Kola, Di̇lek Hacioğlu, Hi̇dayet Erdöl, Adem Türk, Yakup Aslan Jan 2016

Determination Of Regional Screening Criteria For Retinopathy Ofprematurity In The Eastern Black Sea Region Of Turkey, Mehmet Kola, Di̇lek Hacioğlu, Hi̇dayet Erdöl, Adem Türk, Yakup Aslan

Turkish Journal of Medical Sciences

Background/aim: To establish a regional screening protocol for retinopathy of prematurity (ROP). Materials and methods: Data were analyzed from the hospital records of 1241 infants with gestational age (GA) at birth ≤36 weeks and birth weight (BW) of ≤3600 g. Results: The mean GA of the infants was 32.05 ± 2.7 weeks and the mean BW was 1780.5 ± 576 g. ROP at any stage was detected in 703 of the 1241 infants (555 female). Eleven infants with type 1 ROP were treated with 810 nm diode laser photocoagulation. No treatment was needed in infants born after 33 weeks of …


Initial Experience With Delivery Of Palliative Care To Terminal Cancer Patients, Mustafa Süren, İsmai̇l Okan, Zi̇ya Kaya, Serkan Karaman, Semi̇h Arici, Mevlüt Çömlekçi̇, Murat Ayan, Mehmet Esen, Serkan Doğru, Aynur Şahi̇n, Tuğba Karaman Jan 2016

Initial Experience With Delivery Of Palliative Care To Terminal Cancer Patients, Mustafa Süren, İsmai̇l Okan, Zi̇ya Kaya, Serkan Karaman, Semi̇h Arici, Mevlüt Çömlekçi̇, Murat Ayan, Mehmet Esen, Serkan Doğru, Aynur Şahi̇n, Tuğba Karaman

Turkish Journal of Medical Sciences

No abstract provided.


Distribution Of Ldl Subgroups In Patients With Hyperlipidemia, Ebru Taylan, Emi̇ne Pinar Tuncel Jan 2016

Distribution Of Ldl Subgroups In Patients With Hyperlipidemia, Ebru Taylan, Emi̇ne Pinar Tuncel

Turkish Journal of Medical Sciences

Background/aim: Low-density lipoproteins (LDLs) have been shown to be a major risk factor for coronary artery disease. Multiple distinct subspecies have been identified among LDL particles on the basis of differences in size, density, and chemical composition. Particles with a diameter of


Management Of Hyperbilirubinemia In Preterm Infants In Turkey, Ni̇lüfer Güzoğlu, Ümi̇t Ayşe Tandircioğlu, Di̇dem Ali̇efendi̇oğlu Jan 2016

Management Of Hyperbilirubinemia In Preterm Infants In Turkey, Ni̇lüfer Güzoğlu, Ümi̇t Ayşe Tandircioğlu, Di̇dem Ali̇efendi̇oğlu

Turkish Journal of Medical Sciences

Background/aim: Prematurity is a significant risk factor for developing unconjugated hyperbilirubinemia. This study investigated the current approach to managing hyperbilirubinemia in preterm newborns in Turkey. Materials and methods: A study-specific questionnaire on the management of jaundice in preterm infants was sent to 100 level III neonatal intensive care units in Turkey. Results: Responses were obtained from 84 centers from all regions of Turkey. Of the centers, 75.3% used the Turkish Neonatology Society guidelines for deciding to start phototherapy, and 24.7% used different guidelines. The monitoring of bilirubin varied among the participants. Of the participants, 53.6% believed that prophylactic phototherapy was …


The Effect Of Enteral Immunonutrition In Upper Gastrointestinalsurgery For Cancer: A Prospective Study, Seli̇m Yi̇ği̇t Yildiz, Murat Burç Yazicioğlu, Çağri Ti̇ryaki̇, Ali̇ Çi̇ftçi̇, Zehra Boyacioğlu, Mehmet Özyildiz, Murat Coşkun, Özkan Subaşi Jan 2016

The Effect Of Enteral Immunonutrition In Upper Gastrointestinalsurgery For Cancer: A Prospective Study, Seli̇m Yi̇ği̇t Yildiz, Murat Burç Yazicioğlu, Çağri Ti̇ryaki̇, Ali̇ Çi̇ftçi̇, Zehra Boyacioğlu, Mehmet Özyildiz, Murat Coşkun, Özkan Subaşi

Turkish Journal of Medical Sciences

Background/aim: Enteral feeding and immunonutrition (ImN) have been shown to be associated with a number of favorable effects in patients undergoing cancer surgery. In this prospective study, we aimed to assess the perioperative use of enteral immunonutrition in patients undergoing radical gastrointestinal surgery for malignancy. Materials and methods: Forty-one patients with malignancy were included in this study and were randomized into one of the two following nutritional strategies: enteral only (EN) or enteral with enteral immunonutrition (ENIN). These regimens were followed for 7 days perioperatively by all patients. Nutritional parameters and postoperative morbidity, mortality, and length of hospital stay (LHS) …


Evaluation And Identification Of Idua Gene Mutations In Turkishpatients With Mucopolysaccharidosis Type I, Nazente Atçeken, Riza Köksal Özgül, Di̇dem Yücel Yilmaz, Ayşegül Tokatli, Turgay Coşkun, Hati̇ce Serap Si̇vri̇, Ali̇ Dursun, Mehmet Karaca Jan 2016

Evaluation And Identification Of Idua Gene Mutations In Turkishpatients With Mucopolysaccharidosis Type I, Nazente Atçeken, Riza Köksal Özgül, Di̇dem Yücel Yilmaz, Ayşegül Tokatli, Turgay Coşkun, Hati̇ce Serap Si̇vri̇, Ali̇ Dursun, Mehmet Karaca

Turkish Journal of Medical Sciences

Background/aim: This study aimed to identify IDUA gene mutations in Turkish patients morphologically (phenotypic) diagnosed with MPS type I. It also sought to discuss the possible effects of detected mutations on alpha-L-iduronidase enzyme function based on current knowledge. Materials and methods: Genetic analysis was carried out in 15 patients using direct DNA sequencing. Moreover, segregation analysis was performed among family members to predict the pathogenic effect of novel mutations, and computational programs were used to predict their functional impact. Results: Nine different mutations (c.494-1G>A, c.793-6C>G, c.793-5C>A, p.M1L, p.Y64X, p.A327P, p.W402X, p.P533L, and p.R628X) were identified. Computational analysis …


The Role Of Baseline Ga-68 Dotatate Positron Emission Tomography/Computed Tomography In The Prediction Of Response To Fixed-Dose Peptide Receptor Radionuclide Therapy With Lu-177 Dotatate*, Çi̇ğdem Soydal, Ahmet Peker, Elgi̇n Özkan, Nuri̇ye Özlem Küçük, Kemal Meti̇n Kir Jan 2016

The Role Of Baseline Ga-68 Dotatate Positron Emission Tomography/Computed Tomography In The Prediction Of Response To Fixed-Dose Peptide Receptor Radionuclide Therapy With Lu-177 Dotatate*, Çi̇ğdem Soydal, Ahmet Peker, Elgi̇n Özkan, Nuri̇ye Özlem Küçük, Kemal Meti̇n Kir

Turkish Journal of Medical Sciences

Background/aim: To describe the role of baseline gallium (Ga)-68 DOTATATE positron emission tomography (PET)/computed tomography (CT) in the prediction of the response to peptide receptor radionuclide therapy (PRRT) using lutetium (Lu)-177 DOTATATE. Materials and methods: Analysis was made of baseline Ga-68 DOTATATE PET/CT images of 29 patients (17 females and 12 males; mean age: 50.7 ± 14.6 years) with metastatic neuroendocrine tumors who received PRRT with Lu-177 DOTATATE. Maximum standardized uptake values (SUVmax) of reference lesions and their ratios to physiological uptake organs were calculated. The relationship between these values and the radiological response was analyzed. Results: Partial response was …


Genetic Association Of The Col1a1 Gene Promoter ?1997 G/T (Rs1107946) Andsp1 +1245 G/T (Rs1800012) Polymorphisms And Keloid Scars In A Jeddah Population, Sabah A. Linjawi, Sanaa E. Tork, Risa M. Shabiah Jan 2016

Genetic Association Of The Col1a1 Gene Promoter ?1997 G/T (Rs1107946) Andsp1 +1245 G/T (Rs1800012) Polymorphisms And Keloid Scars In A Jeddah Population, Sabah A. Linjawi, Sanaa E. Tork, Risa M. Shabiah

Turkish Journal of Medical Sciences

Background/aim: Scars develop at the end of the natural wound-healing process and are characterized by excessive collagen deposition, particularly types I and III collagen. This study aimed to investigate the genetic association of COL1A1 ?1997 G/T (rs1107946) and COL1A1 Sp1 +1245 G/T (rs1800012) polymorphisms with the incidence of scars. Materials and methods: A case-control association study was conducted with 84 volunteers from Jeddah, Saudi Arabia (47 patients and 37 controls). The allele frequency distribution and nucleotide genotypes of ?1997 G/T, +1245 G/T were ascertained by polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) analysis. Results: Our results indicated …


Posterior Laminoforaminotomy In The Treatment Of Lateralcervical Herniated Disc And Foraminal Stenosis, Hakan Yilmaz, Ali̇ Riza Ertürk, Ayşe Karataş, İbrahi̇m Burak Atci, Alaetti̇n Yurt Jan 2016

Posterior Laminoforaminotomy In The Treatment Of Lateralcervical Herniated Disc And Foraminal Stenosis, Hakan Yilmaz, Ali̇ Riza Ertürk, Ayşe Karataş, İbrahi̇m Burak Atci, Alaetti̇n Yurt

Turkish Journal of Medical Sciences

Background/aim: Posterior cervical laminoforaminotomy is an effective surgical treatment in selected cases of cervical radiculopathy caused by posterolateral herniated discs or foraminal stenosis. The aim of the present study was to evaluate the surgical techniques, rates of complications, long-term outcomes, advantages, and disadvantages of keyhole foraminotomy retrospectively. Materials and methods: Keyhole foraminotomy was performed in 83 patients. In 51 patients (61.5%) soft disc herniation was removed, and in 32 of them (38.5%) osteophytes were evident. The clinical data were evaluated according to Odom's criteria, and the mean follow-up time was 6 months. Results: Postoperative results were classed as excellent in …


Common Variable Immunodeficiency In Adults Requires Reserved Protocols For Long-Term Follow-Up, Ahmet Zafer Çalişkaner, İsmai̇l Rei̇sli̇, Şevket Arslan, Ramazan Uçar, Hüseyi̇n Ataseven, Nedi̇m Yilmaz Selçuk Jan 2016

Common Variable Immunodeficiency In Adults Requires Reserved Protocols For Long-Term Follow-Up, Ahmet Zafer Çalişkaner, İsmai̇l Rei̇sli̇, Şevket Arslan, Ramazan Uçar, Hüseyi̇n Ataseven, Nedi̇m Yilmaz Selçuk

Turkish Journal of Medical Sciences

Background/aim: The aim of this study is to establish follow-up protocols for adult patients with common variable immunodeficiency (CVID) in a recently founded adult immunology clinic in the Central Anatolia Region of Turkey, where a clinical immunology center for adults was not available previously. Materials and methods: A total of 25 patients with CVID aged 18 years and older were included in this study. The file format consisted of 13 pages and was developed for the purpose of the study. Separate sections were designated for identity information, medical history, disease course, previous and current laboratory and imaging studies, follow-up plans, …


Is Silicone Stent Insertion A Clinically Useful Option For Tracheobronchomalacia?, Levent Dalar, Seda Tural Önür, Cengi̇z Özdemi̇r, Si̇nem Nedi̇me Sökücü, Ahmet Levent Karasulu, Sedat Altin Jan 2016

Is Silicone Stent Insertion A Clinically Useful Option For Tracheobronchomalacia?, Levent Dalar, Seda Tural Önür, Cengi̇z Özdemi̇r, Si̇nem Nedi̇me Sökücü, Ahmet Levent Karasulu, Sedat Altin

Turkish Journal of Medical Sciences

Background/aim: Tracheobronchomalacia (TBM) leads to the obstruction of expiratory airflow and interference with secretion clearance. Stabilization of the airway wall using a silicon stent or laser coagulation of the posterior wall may be treatment options.1397645907This study aimed to retrospectively analyze which interventional bronchoscopic method could be used to provide airway stabilization and gain control of symptoms and for whom this method could be used. Materials and methods: Fifteen patients who had received treatment in our interventional pulmonology unit were analyzed. We analyzed the techniques used, stent duration, complications, and long-term treatment success retrospectively. Results: Stents were used in 10 patients: …


Physical Activity And Physical Fitness In Obese, Overweight, And Normal-Weight Children, Juozas Raistenskis, Aurelija Sidlauskiene, Birute Strukcinskiene, Serpi̇l Uğur Baysal, Raimondas Buckus Jan 2016

Physical Activity And Physical Fitness In Obese, Overweight, And Normal-Weight Children, Juozas Raistenskis, Aurelija Sidlauskiene, Birute Strukcinskiene, Serpi̇l Uğur Baysal, Raimondas Buckus

Turkish Journal of Medical Sciences

Background/aim: The aim was to assess the differences between physical activity and physical fitness in obese, overweight, and normal-weight children. Materials and methods: The cross-sectional study was accomplished using cluster sampling method at 3 Lithuanian schools. An analysis of anthropometric data for 532 Lithuanian children was performed. Height, weight, waist and hip circumferences, and skinfold thickness were measured. Body mass index, waist-to-hip ratio, and body fat percentage were calculated. The Youth Physical Activity Questionnaire and a 6-min walk test (6MWT) were administered to evaluate physical activity and physical fitness. Maximal oxygen consumption was calculated to assess the children's aerobic capacity. …


The Prevalence Of Tularemia In Occupational Groups That Have Contact With Animals, Fati̇h Büyük, Özgür Çelebi̇, Eli̇f Çeli̇k, Beki̇r Çelebi̇, Selçuk Kiliç, Ali̇ye Gülmez Sağlam, Doğan Akça, Mehmet Doğanay, Sali̇h Otlu, Mi̇tat Şahi̇n Jan 2016

The Prevalence Of Tularemia In Occupational Groups That Have Contact With Animals, Fati̇h Büyük, Özgür Çelebi̇, Eli̇f Çeli̇k, Beki̇r Çelebi̇, Selçuk Kiliç, Ali̇ye Gülmez Sağlam, Doğan Akça, Mehmet Doğanay, Sali̇h Otlu, Mi̇tat Şahi̇n

Turkish Journal of Medical Sciences

Background/aim: The aim of the current study was to investigate the presence of antibodies against Francisella tularensis in individuals in different occupations that have contact with animals in the Kars region of northeastern Turkey. Materials and methods: A total of 201 blood samples specifically including 103 farmers, 45 clinical veterinarians, 42 butchers, and 11 hunters were analyzed. The results of the study were reported in relation to some sociodemographic features (age, sex, occupation, and experience) of the volunteers. The presence of antibodies was determined by a microagglutination (MA) test. In addition, positive sera were confirmed using an ELISA kit. Results: …


Review Of 306 Evisceration Surgeries Performed Between 2005 And 2013, Özgür Balta, Uğur Acar, Fatma Akbaş Kocaoğlu, Fi̇rdevs Örnek Jan 2016

Review Of 306 Evisceration Surgeries Performed Between 2005 And 2013, Özgür Balta, Uğur Acar, Fatma Akbaş Kocaoğlu, Fi̇rdevs Örnek

Turkish Journal of Medical Sciences

Background/aim: The purpose of the present study was to evaluate the reasons for eye evisceration surgeries performed from 2005 to 2013 in our clinic. Materials and methods: The medical records of patients who underwent evisceration surgery over the past 9 years were retrospectively evaluated. Detailed data were reviewed, with a focus on the first precipitating factor for evisceration. Results: Of the 306 patients who underwent evisceration surgery in the studied period, 111 (36.27%) were female (with a mean age of 41.56 ± 21.38 years) and 195 (63.73%) were male (with a mean age of 37.76 ± 21.92 years). The most …