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Full-Text Articles in Medicine and Health Sciences
Association Of Cardiovascular Factors And Alzhemer's Disease Plasma Amyloid-Beta Protein In Subjective Memory Complainers, Kristyn Bates, Hamid Sohrabi, Mark Rodrigues, John Beilby, Satvinda Dhaliwal, Kevin Taddei, Arthur Criddle, Megan Wraith, Matthew Howard, Georgia Martins, Athena Paton, Pankaj Mehta, Jonathan Foster, Ian Martins, Nicola Launtenschlager, Frank Mastaglia, Simon Laws, Sam Gandy, Ralph Martins
Association Of Cardiovascular Factors And Alzhemer's Disease Plasma Amyloid-Beta Protein In Subjective Memory Complainers, Kristyn Bates, Hamid Sohrabi, Mark Rodrigues, John Beilby, Satvinda Dhaliwal, Kevin Taddei, Arthur Criddle, Megan Wraith, Matthew Howard, Georgia Martins, Athena Paton, Pankaj Mehta, Jonathan Foster, Ian Martins, Nicola Launtenschlager, Frank Mastaglia, Simon Laws, Sam Gandy, Ralph Martins
Simon Laws
A strong link is indicated between cardiovascular disease (CVD) and risk for developing Alzheimer's disease (AD), which may be exacerbated by the major AD genetic risk factor apolipoprotein Eε4 (APOEε4). Since subjective memory complaint (SMC) may potentially be an early indicator for cognitive decline, we examined CVD risk factors in a cohort of SMC. As amyloid-ε (Aβ) is considered to play a central role in AD, we hypothesized that the CVD risk profile (increased LDL, reduced HDL, and increased body fat) would be associated with plasma Aβ levels. We explored this in 198 individuals with and without SMC (average age …
Use Of Day Centers For Respite By Help-Seeking Caregivers Of Individuals With Dementia, Lyn Phillipson, Sandra C. Jones
Use Of Day Centers For Respite By Help-Seeking Caregivers Of Individuals With Dementia, Lyn Phillipson, Sandra C. Jones
Sandra Jones
Addressing the under utilisation of respite services in caregivers of people with dementia is an important task to improve social support amongst this vulnerable group. This paper utilises theory to conceptualise the behavioural, normative and control beliefs that caregivers of people with dementia associate with the use of out of home day centers for respite. Interviews and focus groups with 36 caregivers were undertaken to explore the beliefs of both users and non-users of services. Whilst service users held positive beliefs, non - users perceived negative outcomes for the care recipient with dementia, or faced barriers associated with their behavioural …
Why Caregivers Of People With Dementia Don't Utilise Out-Of-Home Respite Services, L Phillipson, S C. Jones, C Magee
Why Caregivers Of People With Dementia Don't Utilise Out-Of-Home Respite Services, L Phillipson, S C. Jones, C Magee
Sandra Jones
Carers of people with dementia consistently report an unmet need for respite. Despite this, the overall proportion of carers who utilise available day centre, in-home and residential respite programs tends to be low and, even then, use is often delayed and only at very low intensities. In order to support carers in appropriate and supportive use of respite services, program planners and service providers need a good understanding of the factors influencing use and non-use of respite services. With this in mind, a community based survey of 152 help-seeking caregivers of people with dementia (NSW, Australia) was undertaken to establish …
Dementia, Stigma And Intentions To Help-Seek: A Pilot Study Of Australian Adults 40 To 65 Years, Lyn Phillipson, C Magee, Sandra C. Jones, S Reis, E Skladzien
Dementia, Stigma And Intentions To Help-Seek: A Pilot Study Of Australian Adults 40 To 65 Years, Lyn Phillipson, C Magee, Sandra C. Jones, S Reis, E Skladzien
Sandra Jones
Stigma (prejudice or negative stereotypes associated with personal attributes such the presence of ill health or disease) is an important concept as it has the potential to adversely impact on social exclusion, help seeking behaviours and the utilisation of health and social services. Whilst limited international research suggests that there may be stigma associated with dementia, this paper presents results from the first comprehensive study to explore stigma towards dementia in Australia. Results from an online survey of Australian adults (45-60 years) outline the nature and presence of negative attitudes or stereotypes towards dementia and people living with dementia, and …
Potentially Inappropriate Use Of Antipsychotics In Community-Dwelling Adults With Dementia More Common In Those With Low Income, Jennifer Tjia
Potentially Inappropriate Use Of Antipsychotics In Community-Dwelling Adults With Dementia More Common In Those With Low Income, Jennifer Tjia
Jennifer Tjia
Comment on: The essential and potentially inappropriate use of antipsychotics across income groups: an analysis of linked administrative data. [Can J Psychiatry. 2012]
Evidence-Based Guideline: Wandering, May Futrell, Karen Melillo, Ruth Remington
Evidence-Based Guideline: Wandering, May Futrell, Karen Melillo, Ruth Remington
Ruth Remington
No abstract provided.
A Vitamin/Nutriceutical Formulation Improves Memory And Cognitive Performance In Community-Dwelling Adults Without Dementia, A Chan, Ruth Remington, E Kotlya, A Lepore, J Zemianek, Thomas Shea
A Vitamin/Nutriceutical Formulation Improves Memory And Cognitive Performance In Community-Dwelling Adults Without Dementia, A Chan, Ruth Remington, E Kotlya, A Lepore, J Zemianek, Thomas Shea
Ruth Remington
Adults of both genders without dementia consumed a nutriceutical formulation ("NF," consisting of folic acid, B12, Vitamin E, S-adenosylmethionine, N-acetyl cysteine and Acetyl-L-carnitine), previously shown to improve cognitive performance in Alzheimer's disease, or placebo. Participants receiving NF but not placebo improved statistically and clinically in the California Verbal Learning Test II and the Trail-Making Test. Both groups improved further during a 3-month open-label extension. Additional individuals displayed identical improvement during a separate 6-month open-label trial. Performance declined to baseline following withdrawal of NF, and statistically improved when participants resumed taking NF. Additional participants receiving NF but not placebo demonstrated improvement …
Dementia And Risk Of Adverse Warfarin-Related Events In The Nursing Home Setting, Jennifer Tjia, Terry Field, Kathleen Mazor, Jennifer Donovan, Abir Kanaan, George Reed, Peter Doherty, Leslie Harrold, Jerry Gurwitz
Dementia And Risk Of Adverse Warfarin-Related Events In The Nursing Home Setting, Jennifer Tjia, Terry Field, Kathleen Mazor, Jennifer Donovan, Abir Kanaan, George Reed, Peter Doherty, Leslie Harrold, Jerry Gurwitz
Jennifer Tjia
BACKGROUND: Little attention has been focused on the safety of medications administered to treat non illnesses in nursing home residents with dementia. It is unclear whether this population is at increased risk of adverse drug events. OBJECTIVES: To test the hypotheses that in nursing home residents with dementia prescribed warfarin have less time in therapeutic range and a higher incidence of nonpreventable and preventable adverse warfarin events compared to nursing home residents without dementia after controlling for facility and patient characteristics. METHODS: A prospective cohort embedded in a clinical trial of nursing home residents prescribed warfarin in 26 nursing homes …