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Full-Text Articles in Medicine and Health Sciences
Association Between Applications Scores And Positive Onsite Interviews Of Pharmacy Residency Applicants, Sarah Nisly, Meredith L. Howard, Alex N. Issacs, Tate Trujillo
Association Between Applications Scores And Positive Onsite Interviews Of Pharmacy Residency Applicants, Sarah Nisly, Meredith L. Howard, Alex N. Issacs, Tate Trujillo
Sarah A. Nisly
Application to pharmacy residency programs has become increasingly competitive over the past several years. Although successful candidates must excel in the various stages of the application process, preparing written applications and securing onsite interviews are early and arguably the most difficult steps. Residency programs vary in the criteria used for offering onsite interviews. The majority of insight into this topic comes from surveys of residency program directors, but corresponding analyses of interview offers have been minimal...
Evaluation And Revision Of An Introduction To Experiential Rotations Course, Eliza A. Dy, Sarah Nisly
Evaluation And Revision Of An Introduction To Experiential Rotations Course, Eliza A. Dy, Sarah Nisly
Sarah A. Nisly
The objectives of this study were to evaluate the perceived student value of topics taught in Butler University’s Introduction to Experiential Rotations (RX500) course, implement course revisions to address any perceived weaknesses, and to reassess the course following implementation of those course revisions. Advanced Pharmacy Practice Experience (APPE) students from Butler University’s 2012 doctorate of pharmacy class were initially surveyed to assess the perceived usefulness and design of RX500. Based on the findings of the initial data, course revisions were developed and implemented for the following semester’s RX500 course. In order to assess for potential changes in the perceived value …
Aspirin Dosing For The Prevention And Treatment Of Ischemic Stroke: An Indication-Specific Review Of The Literature, Alexander J. Ansara, Sarah A. Nisly, Sally A, Arif, Julia M. Koehler, Sarah T, Nordmeyer
Aspirin Dosing For The Prevention And Treatment Of Ischemic Stroke: An Indication-Specific Review Of The Literature, Alexander J. Ansara, Sarah A. Nisly, Sally A, Arif, Julia M. Koehler, Sarah T, Nordmeyer
Sarah A. Nisly
OBJECTIVE: To evaluate the efficacy of aspirin for the treatment and prevention of ischemic stroke and identify the minimum dose proven to be effective for each indication. DATA SOURCES: PubMed and MEDLINE searches (January 2009–January 2010) were performed to identify primary literature, using search terms including aspirin, stroke prevention, acute ischemic stroke, acetylsalicylic acid, atrial fibrillation, myocardial infarction, and carotid endarterectomy. Additionally, reference citations from publications identified were reviewed. STUDY SELECTION AND DATA EXTRACTION: Articles published in English were evaluated and relevant primary literature evaluating the efficacy of aspirin in the prevention of stroke was included in this review. DATA …
Simvastatin: A Risk Factor For Angioedema?, Sarah A. Nisly, Areeba Kara, Tamara B. Knight
Simvastatin: A Risk Factor For Angioedema?, Sarah A. Nisly, Areeba Kara, Tamara B. Knight
Sarah A. Nisly
Objective. To report a case of simvastatin-induced angioedema in a patient with near nightly episodes of orofacial angioedema. Case Summary. A 75-year-old African American female presented to the emergency department with recurrent face, lip, and tongue swelling. The patient described frequent episodes of orofacial edema, with 4 emergency department visits over the previous 6 months. Her home medications were reviewed and simvastatin was identified as a possible contributing medication. Simvastatin was discontinued with resolution of the symptoms during hospitalization and a significant reduction in episodes. Discussion. Drug-induced angioedema has been documented with several agents, most commonly angiotensin-converting enzyme inhibitors. The …
Canagliflozin, A New Sodium-Glucose Co-Transporter 2 Inhibitor, In The Treatment Of Diabetes, Sarah A. Nisly, Denise M. Kolanczyk, Alison M. Walton
Canagliflozin, A New Sodium-Glucose Co-Transporter 2 Inhibitor, In The Treatment Of Diabetes, Sarah A. Nisly, Denise M. Kolanczyk, Alison M. Walton
Sarah A. Nisly
Purpose. The published evidence on the pharmacology, pharmacodynamics, pharmacokinetics, safety, and efficacy of a promising investigational agent for managing type 2 diabetes is evaluated. Summary. Canagliflozin belongs to a class of agents—the sodium–glucose cotransporter 2 (SGLT2) inhibitors—whose novel mechanism of action offers potential advantages over other antihyperglycemic agents, including a relatively low hypoglycemia risk and weight loss-promoting effects. Canagliflozin has dose-dependent pharmacokinetics, and research in laboratory animals demonstrated high oral bioavailability (85%) and rapid effects in lowering glycosylated hemoglobin (HbA1c) values. In four early-stage clinical trials involving a total of over 500 patients, the use of canagliflozin for varying periods …
Lipid Goals: Update On Their Status, Katie Axford, Eliza Dy, Sarah A. Nisly
Lipid Goals: Update On Their Status, Katie Axford, Eliza Dy, Sarah A. Nisly
Sarah A. Nisly
Goal: The goal of this lesson is to discuss current medical management of dyslipidemias, including available agents and goals of therapy, as well as potential future treatment strategies based on recently published literature.
Use Of A Subcutaneous Insulin Computerized Glucostabilizer™ Program On Glycemic Control In The Intensive Care Setting: A Retrospective Data Analysis., Sarah A. Nisly, Serena Harris, Laura Aykroyd, Joni Carrol, Brian Ulmer, Michael Waddell, Samuel Flanders, Rattan Juneja
Use Of A Subcutaneous Insulin Computerized Glucostabilizer™ Program On Glycemic Control In The Intensive Care Setting: A Retrospective Data Analysis., Sarah A. Nisly, Serena Harris, Laura Aykroyd, Joni Carrol, Brian Ulmer, Michael Waddell, Samuel Flanders, Rattan Juneja
Sarah A. Nisly
Background: Despite guidelines that recommend strongly against Sliding Scale Insulin (SSI) it continues to be the most commonly insulin regimen used in hospitals to treat hyperglycemia. In addition to being reactionary to a glucose that has already increased, SSI offers practical challenges in the randomness of the doses of insulin prescribed and often a disconnect with glucose testing that should be occurring in congruence to the insulin dosing. While many clinical trials have shown improved glycemic control in critical care patients receiving intravenous insulin; few studies have demonstrated the efficacy of subcutaneous (SQ) insulin in this setting. In this study, …
Case Study: Weight Loss Leads To Cost Savings And Improvement In Metabolic Syndrome, Kori Trussell, Debbie Hinnen, Patrick Gray, Sarah Nisly, Karissa Bratcher, Helen Ramsey, James Early
Case Study: Weight Loss Leads To Cost Savings And Improvement In Metabolic Syndrome, Kori Trussell, Debbie Hinnen, Patrick Gray, Sarah Nisly, Karissa Bratcher, Helen Ramsey, James Early
Sarah A. Nisly
Case Study reporting the effects of weight loss as a means of improving Metabolic Syndrome.
Tobramycin-Induced Hepatotoxicity, Sarah A. Nisly, Shaunta' M. Ray, Robert A. Moye
Tobramycin-Induced Hepatotoxicity, Sarah A. Nisly, Shaunta' M. Ray, Robert A. Moye
Sarah A. Nisly
OBJECTIVE. To report a case of tobramycin-induced hepatotoxicity. CASE SUMMARY: A 20-year-old female was hospitalized for treatment of Pseudomonas aeruginosa bacteremia and osteomyelitis. Empiric intravenous antibiotic therapy with piperacillin/tazobactam, vancomycin, and ciprofloxacin was started, and based on the results of culture and sensitivity testing, was changed to intravenous ceftazidime and tobramycin 70 mg every 8 hours on hospital day 3. Liver enzyme levels then increased over days 3–6. Tests for hepatitis A, B, and C were all nonreactive, and HIV testing was negative. On day 8, therapy was changed from ceftazidime to piperacillin/tazobactam and the tobramycin dose was increased to …
Use Of Web-Based Learning Modules For A General Medicine Advanced Pharmacy Practice Experience., Sarah A. Nisly, Alex N. Issacs, Kathryn Givens Merkel
Use Of Web-Based Learning Modules For A General Medicine Advanced Pharmacy Practice Experience., Sarah A. Nisly, Alex N. Issacs, Kathryn Givens Merkel
Sarah A. Nisly
Objective. To implement and assess web-based learning modules on baseline pharmacy student knowledge prior to a general medicine advanced pharmacy practice experience (APPE). Methods. Three web-based learning modules were developed for use prior to a general medicine APPE. Students completed pre- and post-assessments specific to each learning module. Additionally, students completed perception surveys at the conclusion of the APPE to determine the utility of these modules and the impact on student learning experiences. Results. Use of the web-based training (WBT) modules resulted in a statistically significant improvement in post-assessment scores for two of the three modules (p < 0.001). Student participants …
Dietary Supplement Education In A Senior Population, Kimberly G. Elder, Sarah A. Nisly
Dietary Supplement Education In A Senior Population, Kimberly G. Elder, Sarah A. Nisly
Sarah A. Nisly
Background. Dietary supplements are widely used among United States senior citizens for various indications. Potential dangers with supplement use include the lack of regulation by the Food and Drug Administration (FDA) and the possibility for drug-supplement interactions. Senior focused education may in- crease the safe use of dietary supplements by older adults. Objective. The primary objective of this study was to determine the effectiveness of a pharmacist driven educational seminar in a local senior population. Methods. Participants aged 55 years and older in one of three senior programs were eligible for inclusion. Initially, a needs-assessment interview was con- ducted at …