Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Medicine and Health Sciences
Effects Of Cross-Fostering On Alcohol Preference And Correlated Responses To Selection In High- And Low-Alcohol Preferring Mice, G. D. Barrenha, Julia Chester
Effects Of Cross-Fostering On Alcohol Preference And Correlated Responses To Selection In High- And Low-Alcohol Preferring Mice, G. D. Barrenha, Julia Chester
Department of Psychological Sciences Faculty Publications
Background: Selectively bred rodent lines are valuable tools for investigating gene x environment interactions related to risk for alcoholism in humans. Early maternal environment is one particular factor known for critically influencing neural, hormonal, and behavioral outcomes in adulthood. Cross-fostering is a procedure that may be used to explore the role of genotype-dependent maternal influences on phenotypic variability in adulthood. The purpose of these experiments was to examine the effects of cross-fostering on free-choice alcohol drinking and correlated responses to selection for alcohol preference in mice selectively bred for high- (HAP2) and low- (LAP2) alcohol preference. Methods: Mice were assigned …