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Full-Text Articles in Medicine and Health Sciences
Potential Differences In Male Versus Female Lymph Nodes, Vikas Damineni
Potential Differences In Male Versus Female Lymph Nodes, Vikas Damineni
PCOM Biomedical Studies Student Scholarship
The lymphatic system is one of the latest anatomical organ systems to have been discovered, and as a result, it can be considered the least understood. Limited research exists on the quantitative and qualitative values of lymph nodes. The pelvic and axillary region is anatomically unique for each sex. Observing if this extends to the lymph nodes themselves will create a clearer understanding of the lymphatic system for the medical community. The present study sought to establish potential differences in male and female lymph nodes. Quantitative data of male and female lymph nodes were collected through cadaver dissection. Fifty-three cadavers …
Generation And Application Of Inducible Chimeric Rna, Yichen Luo, Liang Du, Zhimeng Yao, Fan Liu, Kai Li, Feifei Li, Jianlin Zhu, Robert P Coppes, Dianzheng Zhang, Yunlong Pan, Shegan Gao, Hao Zhang
Generation And Application Of Inducible Chimeric Rna, Yichen Luo, Liang Du, Zhimeng Yao, Fan Liu, Kai Li, Feifei Li, Jianlin Zhu, Robert P Coppes, Dianzheng Zhang, Yunlong Pan, Shegan Gao, Hao Zhang
PCOM Scholarly Papers
Chimeric RNAs (chiRNAs) play many previously unrecognized roles in different diseases including cancer. They can not only be used as biomarkers for diagnosis and prognosis of various diseases but also serve as potential therapeutic targets. In order to better understand the roles of chiRNAs in pathogenesis, we inserted human sequences into mouse genome and established a knockin mouse model of the tamoxifen-inducible expression of ASTN2-PAPPA antisense chimeric RNA (A-PaschiRNA). Mice carrying the A-PaschiRNA knockin gene do not display any apparent abnormalities in growth, fertility, histological, hematopoietic, and biochemical indices. Using this model, we dissected the role of …