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Full-Text Articles in Medicine and Health Sciences
Neurobehavior In Humans And Its Role In Alzheimer's Disease, Aghilas Belkadi, Sarah Levin Allen
Neurobehavior In Humans And Its Role In Alzheimer's Disease, Aghilas Belkadi, Sarah Levin Allen
Research Day
In a neurobehavioral lens, a human is defined as the balance of the mind, body, and brain. These systems function on their own and influence each other in a dynamic equilibrium. Interactions between these systems are observed in every aspect of life. A pathological example of this relationship is that depression, a state of mind, can increase the risk of developing cardiovascular diseases. By studying a neurobehavioral model of health, empirical links between psychology and neurobiology can be uncovered. The basis of this capstone is to understand how neurobehavior works in clinical practice. This capstone project involved observation of seniors …
Infection With Chlamydia Pneumoniae Alters Calcium-Associated Gene Regulation And Processes In Neuronal Cells And Monocytes: Implications For Alzheimer’S Disease, Keith G. Williams, Juliana Zoga, Susan T. Hingley, Brian J. Balin, Denah M. Appelt, Marcus G. Bell
Infection With Chlamydia Pneumoniae Alters Calcium-Associated Gene Regulation And Processes In Neuronal Cells And Monocytes: Implications For Alzheimer’S Disease, Keith G. Williams, Juliana Zoga, Susan T. Hingley, Brian J. Balin, Denah M. Appelt, Marcus G. Bell
Research Day
Background: First proposed by Khachaturian in 1994, the calcium hypothesis postulates that sustained disturbance of intracellular calcium is the leading cause of neurodegenerative disorders. Studies showing alteration in calcium signaling in both sporadic and familial Alzheimer’s disease (AD) support this hypothesis. Intracellular calcium signaling is tightly regulated in time, intensity, and space, and is responsible for a variety of neuronal functions. Calcium influx from the extracellular environment modulates calcium levels, as do intracellular stores in the endoplasmic reticulum. The focus of this study was to test various calcium related genes in both monocytes and neuronal cells. Previous studies have shown …