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Medicine and Health Sciences Commons

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Philadelphia College of Osteopathic Medicine

Research Day

2018

Wound healing

Articles 1 - 2 of 2

Full-Text Articles in Medicine and Health Sciences

The $94 Billion Problem: Application Of Safe Acid Technology (Sat) To Combat Biofilm Infections, Katherine Mulquin, Benjamin Lam, Christopher Capicotto, Olivia Questore May 2018

The $94 Billion Problem: Application Of Safe Acid Technology (Sat) To Combat Biofilm Infections, Katherine Mulquin, Benjamin Lam, Christopher Capicotto, Olivia Questore

Research Day

Purpose: Biofilm infections present a major public health threat. In the U.S. alone, biofilm infections are implicated in up to 550,000 yearly fatalities with an estimated annual cost of $94 billion. Biofilm infections are difficult to treat, as biofilm-secreting bacteria are highly resistant to host immune responses. We hypothesize that Safe Acid Technology (SAT), a unique acid formulation, may reduce the risk of biofilm infections while maximizing patient safety.

Methods: SAT anti-biofilm testing was administered by the Montana State University Center for BioFilm Engineering using a single species (Pseudomonas aeruginosa) biofilm grown in the CDC reactor according …


Bioactive Peptides™ To Aid In Healing Of Chronic Skin Wounds And Tissue Repair, Elizabeth Brehman, Jonathan Mclaughlin, Stephanie Scianni, Charlotte H. Greene Phd, George Petito May 2018

Bioactive Peptides™ To Aid In Healing Of Chronic Skin Wounds And Tissue Repair, Elizabeth Brehman, Jonathan Mclaughlin, Stephanie Scianni, Charlotte H. Greene Phd, George Petito

Research Day

When wound healing of cutaneous tissue becomes problematic, it increases patient morbidity associated with increased infection, demand on medical resources, and asserts a profound detrimental effect on the individual’s quality of life. Currently, there are limited effective strategies for addressing chronic cutaneous wounds. The study reported here is based upon the understanding that individual skin wounds may preferentially require differing proteinaceous precursors during specific phases of skin wound repair and calls attention to the possibilities in the reexamination of traditional treatments such as plant and animal-derived substances among many others. This study aimed to determine if, and which, amino acid …