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Philadelphia College of Osteopathic Medicine

Research Day

Pharmacy and Pharmaceutical Sciences

Phase 3 trial

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Safety And Efficacy Of Brexanolone As A Novel Treatment Option For Postpartum Depression: A Systematic Review., Husna Rahim, Barry Brown May 2023

Safety And Efficacy Of Brexanolone As A Novel Treatment Option For Postpartum Depression: A Systematic Review., Husna Rahim, Barry Brown

Research Day

Introduction: With the recognition of postpartum depression as a distinct medical condition since the release of the 2013 DSM-V, there simultaneously arose a need for therapy. As of March 2019, brexanolone became the first FDA approved medication indicated for the treatment of postpartum depression. The purpose of this review is to consolidate and present the safety and efficacy data of a new treatment option for postpartum depression.

Methods: A date range was specified of January 2015 to May 2022 with the last search being conducted June 28, 2022. Cochrane, PubMed, Embase, and Google Scholar were utilized to identify appropriate trials. …