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Philadelphia College of Osteopathic Medicine

Internal Medicine Resident Research

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Full-Text Articles in Medicine and Health Sciences

Antineutrophil Cytoplasmic Autoantibody-Associated Glomerulonephritis As A Possible Side Effect Of Covid-19 Vaccination., Edva Noel, Urmiya Rashid, Rizwan Rabbani, Waqas Ahmad Khan, Yves-Smith Benjamin, Iris Lee Oct 2022

Antineutrophil Cytoplasmic Autoantibody-Associated Glomerulonephritis As A Possible Side Effect Of Covid-19 Vaccination., Edva Noel, Urmiya Rashid, Rizwan Rabbani, Waqas Ahmad Khan, Yves-Smith Benjamin, Iris Lee

Internal Medicine Resident Research

Vaccination is the principal tool aimed at curbing the COVID-19 pandemic that has, so far, affected tens of millions of individuals in the United States. The two available mRNA vaccines developed by Pfizer-BioNTech and Moderna possess high efficacy in preventing infection and illness severity. However, there are multiple side effects associated with these vaccines, some impacting different organs. Renal pathology is variable, with increasing cases of glomerulonephritis being observed. We report a rare acute kidney injury case due to antineutrophil cytoplasmic autoantibody (ANCA)-mediated glomerulonephritis after administering a second dose of the Pfizer-BioNTech mRNA SARS-CoV-2 vaccine. Aggravation and/or development of autoimmunity …