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Medicine and Health Sciences Commons

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Philadelphia College of Osteopathic Medicine

Skin and Connective Tissue Diseases

Hyperhidrosis

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Is Prophylactic Oxybutynin Safe And Effective In Reducing The Severity Of Palmar Hyperhidrosis In Adults?, Kristin K. Amicone Jan 2015

Is Prophylactic Oxybutynin Safe And Effective In Reducing The Severity Of Palmar Hyperhidrosis In Adults?, Kristin K. Amicone

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine “Is prophylactic oxybutynin safe and effective in reducing the severity of palmar hyperhidrosis in adults?”

STUDY DESIGN: This review is based on two randomized controlled trials (RCTs) and one non-randomized crossover study published in 2008, 2011, and 2012. The studies compared the safety and efficacy of oxybutynin in reducing the severity of palmar hyperhidrosis.

DATA SOURCES: All articles used were published in English, in peer-reviewed journals, and found using PubMed, Ebscohost, and Cochrane Review databases.

OUTCOMES MEASURED: For all studies, the safety and effectiveness of oxybutynin on palmer hyperhidrosis …