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Full-Text Articles in Medicine and Health Sciences
Hereditary Angioedema., Helen Lesser, Jason E Cohn
Hereditary Angioedema., Helen Lesser, Jason E Cohn
Otolaryngology (ENT) Resident Research
A 14-year-old African American female presented to the emergency department with spontaneous, sudden-onset lip swelling for 1 h. On examination, there was significant water-bag edema of the upper lip extending to the philtrum and premaxilla. Nasopharyngeal laryngoscopy revealed a patent airway without edema. She was initiated on intravenous dexamethasone, famotidine, and diphenhydramine, after which her edema improved but did not resolve. She was subsequently transferred to a local pediatric hospital and upon further testing she was found to have a C1 esterase inhibitor de novo gene mutation. Angioedema causes localized, non-pitting edema of the dermis, subcutaneous and submucosal tissue, and …
Speech And Language Outcomes In Patients With Ankyloglossia Undergoing Frenulectomy: A Retrospective Pilot Study, Srihari Daggumati, Jason E. Cohn, Matthew J. Brennan, Marissa Evarts, Brian J. Mckinnon, Alyssa R. Terk
Speech And Language Outcomes In Patients With Ankyloglossia Undergoing Frenulectomy: A Retrospective Pilot Study, Srihari Daggumati, Jason E. Cohn, Matthew J. Brennan, Marissa Evarts, Brian J. Mckinnon, Alyssa R. Terk
Otolaryngology (ENT) Resident Research
Ankyloglossia is a controversial topic with no standardized treatment guidelines. A retrospective chart review was conducted to identify children who underwent lingual frenulectomy for speech and language impairment. Impairment severity was recorded pre- and postoperatively as mild, mild to moderate, moderate, moderate to severe, or severe. Variables were tested with chi-square analysis for their statistical relationship to improvements in speech and language. Children with preoperative moderate and moderate-to-severe speech and language impairment attained better speech and language outcomes after frenulectomy as compared with children with mild and mild-to-moderate impairment (100% vs 82%, P = .015). Sutured closure after frenulectomy was …