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Does The Injection Of Botulinum Toxin Improve Symptoms In Patients With Gastroparesis?, Jillian Solomon
Does The Injection Of Botulinum Toxin Improve Symptoms In Patients With Gastroparesis?, Jillian Solomon
PCOM Physician Assistant Studies Student Scholarship
OBJECTIVE: The objective of this selected EBM review is to determine whether or not the injection of botulinum toxin improves symptoms in patients with gastroparesis.
STUDY DESIGN: Review of two published, double blind randomized controlled trials and one published, open label pilot study were used for this review, which were found on PubMed.
OUTCOMES MEASURED: The outcome was the change in gastroparesis-associated symptoms, which was measured using the Gastroparesis Cardinal Scale Index (GCSI) and Gastroparesis Questionnaire. In the two double blind, randomized controlled trials by Arts et al. and Friendenberg et al., symptoms were quantified using the …